Ichikawa Takafumi

イチカワタカフミ | Ichikawa Takafumi

Affiliation and department：
Job title： Assistant Professor

Research field (3)： Gastroenterology , Pathobiochemistry , Pharmacology

Research keywords (6)：薬理学 , 生化学 , 消化器病学 , Pharmacology , Biochemistry , Gastroenterology

Research theme for competitive and other funds (22)：

2021 - 2025 Regulation mechanism of host immune response by S100-like proteins from parasite helminths
2020 - 2023 水分保持力を軸にしたムチン機能における腸内細菌叢由来代謝物の関連性
2019 - 2022 Potential of amino acid transporter as a marker for inflammation of intestinal mucosa
2017 - 2021 Role of prostanoid in demyelination and remyelination.
2017 - 2021 Mechanisms of the water retention into the intestinal mucin that fluctuates depending on the pathological condition

2016 - 2020 Regulation of the injury via the histamine H2 receptor pathway in the small intestine

2013 - 2016 Clarification of autophagy mechanisms to tracking from exocrine secretory granule membrane

2003 - 2006 Neurotrophic factors and gastrointestinal mucosa

2001 - 2002 Homeostasis of gastric mucosa and effects of peptidergic nerve on mucus metabolism

2000 - 2001 A systematic development of monoclonal antibodies against mucins of digestive tract and their application to pathophysiological studies

1999 - 2000 胃粘膜防御機構を制御する受容体の分布と発現及び関連する情報物質ネットワークの検証

1997 - 1998 Role of the gastric mucus on the Helicobacter pylori infection.

1997 - 1998 各種神経ペプチドの胃粘膜内の詳細な局在と粘膜防御機構の制御に果たす役割との関連性

1996 - 1996 一酸化窒素代謝系が各種内在性調節因子による胃粘膜防御機構の制御に果たす役割

1995 - 1996 How dose the gastric surface mucus cell line derived from transgenic mouse synthesize and secrete mucins?

1995 - 1995 増殖因子などの内在性調節因子により胃粘膜防御機はどのように制御されているか

1994 - 1994 胃粘液防御機構の内在性調節因子の解明と加齢による調節機構変動に関する実験的研究

1991 - 1992 Measurement of rat gastric mucus secretion using ex-vivo gastric chamber system

抗潰瘍治療薬の胃粘液代謝に及ぼす影響に関する研究

消化管ムチン生合成の調節機構に関する研究

Study on the effects of anti-ulcer drugs on mucin metabolism

Study on the regulatory mechanism of mucin biosynthesis in digestive tract.

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Papers (90)：

Moragot Chatatikun, Hiroko P. Indo, Motoki Imai, Fumitaka Kawakami, Makoto Kubo, Yoshimasa Kitagawa, Hiroshi Ichikawa, Lunla Udomwech, Atthaphong Phongphithakchai, Orawan Sarakul, et al. Potential of traditional medicines in alleviating COVID-19 symptoms. Frontiers in Pharmacology. 2024. 15
Daisuke Masuda, Ikuo Nakanishi, Kei Ohkubo, Hiromu Ito, Ken-ichiro Matsumoto, Hiroshi Ichikawa, Moragot Chatatikun, Wiyada Kwanhian Klangbud, Manas Kotepui, Motoki Imai, et al. Mitochondria Play Essential Roles in Intracellular Protection against Oxidative Stress-Which Molecules among the ROS Generated in the Mitochondria Can Escape the Mitochondria and Contribute to Signal Activation in Cytosol?. Biomolecules. 2024. 14. 1. 128-128
Rei Kawashima, Daigo Tsubokawa, Katsunori Iijima, Takafumi Ichikawa. Extraction and Fractionation of Human Gastric Mucins from Gastric Juice. Methods in molecular biology (Clifton, N.J.). 2024. 2763. 61-69
Daigo Tsubokawa, Rei Kawashima, Takafumi Ichikawa. Structural Elucidation of Sialylated O-Glycan Alditols Obtained from Mucins by Mass Spectrometry. Methods in molecular biology (Clifton, N.J.). 2024. 2763. 209-221
Fumitaka Kawakami, Motoki Imai, Yuki Isaka, Mark R. Cookson, Hiroko Maruyama, Makoto Kubo, Matthew J. Farrer, Makoto Kanzaki, Rei Kawashima, Tatsunori Maekawa, et al. LRRK2 negatively regulates glucose tolerance via regulation of membrane translocation of GLUT4 in adipocytes. FEBS Open Bio. 2023

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MISC (72)：

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Books (3)：

Education (4)：

Professional career (1)：

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