Ohiro Yoichi

Affiliation and department：
Job title： Professor

Research field (1)： Surgical dentistry

Research keywords (2)：口腔顎顔面外科学 , Oral and Maxillofacial Surgery

Research theme for competitive and other funds (24)：

2021 - 2024 がんと腫瘍血管の相互作用による新たな転移促進機構の解明とその制御
2021 - 2024 Development of new anti-cancer strategy via activation of immunity by targeting tumor endothelial factors
2019 - 2022 エナメル上皮腫の浸潤機構解明による新規治療法の開発
2019 - 2022 Association between oral bacteria and oral cancer metastasis
2018 - 2021 Elucidation of the mechanism for cancer metastasis induced by oral cancer exosome and development of novel therapy for metastatic cancer

2013 - 2016 Development of new treatment strategy targeting for vascular niche of oral cancer stem cell

2012 - 2015 Development of novel therapy targeting cancer stem cells by ROS regulation

2010 - 2012 Original approach to obtain intrinsic resistance genes to cisplatin

2008 - 2011 Exploitation of gene-targeting therapy based on the cellular and biological features of oral-carcinoma stem cell and tumor microenvironment.

2007 - 2009 Detection of cervical lymphnode micrometastasis in oral cancer

2007 - 2008 Roles of p53 family proteins on the risk-factor of recurrence in oral squamous cell carcinomas.

2006 - 2007 顎骨骨折・顎骨欠損への再生医療の試み-ポリリン酸による顎骨誘導-

2006 - 2007 Development of gene delivery system using nanocoloid and its application for gene targeting therapy

2006 - 2007 Gene Targeting Therapy against tumor endothelial cells

2005 - 2006 Evaluation of pre-operative Chemoradiotherapy in Oral Squamous Cell Carcinoma. -Integration of molecular biology and clinical state-

2005 - 2006 Roles of Pim-1 oncogene in oral squamous cell carcinoma.

2005 - 2006 An exploitation of gene targeting therapy against hypoxic condition of oral carcinoma.

2004 - 2005 Vascular endothelial growth factor and its receptor to diagnose lymph node metastasis in patients with oral cancer

2004 - 2005 Translation research for predicting the prognosis of oral malignant tumors.

2004 - 2005 Gene targeting therapy for oral carcinoma using adrenomedullin antagonisit.

2003 - 2004 口腔悪性腫瘍術前診断におけるトランスレーショナル・リサーチ

2003 - 2004 カーボンナノチューブによる細胞・組織へのデリバリーシステムの構築

2002 - 2003 Identification of HIF-1a target genes and their biological roles in oral carcinoma.

2002 - 2003 Research on factors involved in prognosis of oral carcinoma.

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Papers (79)：

A case of Applying a Bone Anchored Device for Oligodontia. Journal of Japanese Society of Oral Inmplantology. 2023. 36. 4. 262-267
Tetsuya Seikai, Soichi Tanaka, Naohiro Ogawa, Hirotake Murakami, Yoichi Ohiro. Oronasal fistula: A rare complication of mesiodens. Advances in Oral and Maxillofacial Surgery. 2023. 12. 100453-100453
Yusuke Yokota, Takumi Hasegawa, Nobuhiro Yamakawa, Shin Rin, Mitsunobu Otsuru, Shin-ichi Yamada, Eiji Hirai, Yuichi Ashikaga, Kozo Yamamoto, Michihiro Ueda, et al. Comparison of the 8th edition of TNM staging of oral cancer with the 7th edition and its prognostic significance using clinical depth of invasion and extranodal extension. Oral Oncology. 2023. 145. 106519-106519
Akira Yamagami, Katsuya Narumi, Yoshitaka Saito, Ayako Furugen, Shungo Imai, Yoshimasa Kitagawa, Yoichi Ohiro, Ryo Takagi, Yoh Takekuma, Mitsuru Sugawara, et al. Development of a risk prediction model for surgical site infection after lower third molar surgery. Oral diseases. 2023
足利雄一, 篠原早紀, 関口珠希, 格口渉, 大廣洋一. 下顎エナメル上皮腫に反復処置法を適応し,腫瘍による歯根吸収を伴う歯を無治療で温存した1例. 北海道歯学雑誌. 2023. 44. 73-80

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MISC (6)：

小野寺麻記子, 山崎裕, 秦浩信, 足利雄一, 大廣洋一, 松沢祐介, 小野貢伸, 戸塚靖則, 箕輪和行, 滝波修一, et al. 当施設におけるびまん性硬化性下顎骨骨髄炎の臨床的検討臨床病態について. 日本口腔外科学会雑誌. 2011. 57. Suppl. 137-137
足利雄一, 山崎裕, 秦浩信, 小野寺麻記子, 野谷健一, 北川善政, 松沢祐介, 大廣洋一, 小野貢伸, 箕輪和行, et al. 当施設におけるびまん性硬化性下顎骨骨髄炎の臨床的検討治療効果について. 日本口腔外科学会雑誌. 2011. 57. Suppl. 137-137
笠原和恵, 山田珠希, 山本栄治, 大廣洋一, 戸塚靖則, 北川善政, 飯塚正, 進藤正信. 骨性異形成症の臨床病理学的研究. 日本口腔外科学会雑誌. 2006. 52. Suppl. 135-135
大廣洋一, 細川眞澄男. プロスタグランジンE2による腫瘍免疫の抑制. 臨床免疫. 1997. 29. 1. 1115-1120
大廣洋一, 蔵満保宏, 小林正伸, 松下和裕, 岡田太, 中井一元, 細川真澄男. Enhancement of vaccine effect of PGE2 productive tumor cells by cytokine gene transfer. Biotherapy (Tokyo). 1997. 11. 3. 319

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Books (2)：

Ameloblastoma
University of Indonesia 2019
The Bicon Short Implant: a thirty-year perspective
2018 ISBN:9784781206547

Lectures and oral presentations (88)：

Concept of treatment of oral lesions extending into the maxillary sinus
(The 68th Congress of the Japanese Society of Oral and Maxillofacial Surgeons 2023)
頭頸部アルミノックス治療におけるニードルカテーテル穿刺のためのガイドプレートの製作について
(頭頸部癌 2023)
オトガイ形成術を行った患者における側貌軟組織の変化について
(日本顎変形症学会雑誌 2023)
頭頸部アルミノックス治療におけるニードルカテーテル穿刺のためのガイドプレートの製作について
(頭頸部癌 2023)
Treatment of secondary deformity following free fibula flap mandibule reconstruction using a computer simulation system
(日本口腔腫瘍学会総会・学術大会プログラム・抄録集 2023)

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Education (2)：

1993 - 1997 Hokkaido University Graduate School of Dental Medicine Clinical Oral Medical Science
1986 - 1992 Hokkaido University School of Dentistry

Professional career (1)：

博士(歯学) (北海道大学)

Work history (12)：

2022/04 - 現在 Oral Pathobiological Science, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University Oral and Maxillofacial Surgery Professor
2016/06 - 2022/03 Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University Oral and Maxillofacial Surgery Associate Professor
2012/06 - 2016/05 Department of Oral and Maxillofacial Surgery Hokkaido University School of Dentistry Associate Professor
2007/04 - 2012/05 Department of Oral and Maxillofacial Surgery, Hokkaido University School of Dentistry Assistant Professor
2003/10 - 2007/03 Hokkaido University Dental Hospital Assistant Professor

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Association Membership(s) (8)：

Japanese Society for Jaw Deformities , 日本口腔インプラント学会 , Japanese Society of Oral Oncology , JAPAN SOCIETY OF CLINICAL ONCOLOGY , JAPAN SOCIETY FOR HEAD AND NECK CANCER , Asian Association of Oral and Maxillofacial Surgeons , JAPANESE SOCIETY OF ORAL AND MAXILLOFACIAL SURGEONS , JAPANESE STOMATOLOGICAL SOCIETY

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