Ohiro Yoichi

Affiliation and department：
Job title： Professor

Research field (1)： Surgical dentistry

Research keywords (2)：口腔顎顔面外科学 , Oral and Maxillofacial Surgery

Research theme for competitive and other funds (25)：

2024 - 2027 ベイズモデリングによるデータ同化と位相的データ解析を用いた顎骨切削手術技能評価
2021 - 2024 がんと腫瘍血管の相互作用による新たな転移促進機構の解明とその制御
2021 - 2024 Development of new anti-cancer strategy via activation of immunity by targeting tumor endothelial factors
2019 - 2022 エナメル上皮腫の浸潤機構解明による新規治療法の開発
2019 - 2022 Association between oral bacteria and oral cancer metastasis

2018 - 2021 Elucidation of the mechanism for cancer metastasis induced by oral cancer exosome and development of novel therapy for metastatic cancer

2013 - 2016 Development of new treatment strategy targeting for vascular niche of oral cancer stem cell

2012 - 2015 Development of novel therapy targeting cancer stem cells by ROS regulation

2010 - 2012 Original approach to obtain intrinsic resistance genes to cisplatin

2008 - 2011 Exploitation of gene-targeting therapy based on the cellular and biological features of oral-carcinoma stem cell and tumor microenvironment.

2007 - 2009 Detection of cervical lymphnode micrometastasis in oral cancer

2007 - 2008 Roles of p53 family proteins on the risk-factor of recurrence in oral squamous cell carcinomas.

2006 - 2007 顎骨骨折・顎骨欠損への再生医療の試み-ポリリン酸による顎骨誘導-

2006 - 2007 Development of gene delivery system using nanocoloid and its application for gene targeting therapy

2006 - 2007 Gene Targeting Therapy against tumor endothelial cells

2005 - 2006 Evaluation of pre-operative Chemoradiotherapy in Oral Squamous Cell Carcinoma. -Integration of molecular biology and clinical state-

2005 - 2006 Roles of Pim-1 oncogene in oral squamous cell carcinoma.

2005 - 2006 An exploitation of gene targeting therapy against hypoxic condition of oral carcinoma.

2004 - 2005 Vascular endothelial growth factor and its receptor to diagnose lymph node metastasis in patients with oral cancer

2004 - 2005 Translation research for predicting the prognosis of oral malignant tumors.

2004 - 2005 Gene targeting therapy for oral carcinoma using adrenomedullin antagonisit.

2003 - 2004 口腔悪性腫瘍術前診断におけるトランスレーショナル・リサーチ

2003 - 2004 カーボンナノチューブによる細胞・組織へのデリバリーシステムの構築

2002 - 2003 Identification of HIF-1a target genes and their biological roles in oral carcinoma.

2002 - 2003 Research on factors involved in prognosis of oral carcinoma.

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Papers (87)：

Akira Yamagami, Katsuya Narumi, Yoshitaka Saito, Ayako Furugen, Shungo Imai, Yoshimasa Kitagawa, Yoichi Ohiro, Ryo Takagi, Yoh Takekuma, Mitsuru Sugawara, et al. Reply to Accurate Risk Prediction Model for Surgical Site Infection After Lower Third Molar Surgery. Oral diseases. 2024
Ming-Yi Lu, Chih-Yuan Fang, Pei-Ling Hsieh, Shih-Chi Chao, Yi-Wen Liao, Yoichi Ohiro, Chen-Chia Yu, Dennis Chun-Yu Ho. MIAT promotes myofibroblastic activities and transformation in oral submucous fibrosis through sponging the miR-342-3p/SOX6 axis. Aging. 2024. 16. 19. 12909-12927
Ming-Yi Lu, Pei-Ling Hsieh, Shih-Chi Chao, Chih-Yuan Fang, Yoichi Ohiro, Yi-Wen Liao, Cheng-Chia Yu, Min-Te Chang. Targeting MetaLnc9/miR-143/FSCN1 axis inhibits oxidative stress and myofibroblast transdifferentiation in oral submucous fibrosis. Journal of dental sciences. 2024. 19. 3. 1416-1425
Wataru Kakuguchi, Yuichi Ashikaga, Yasuhito Moritani, Shintaro Nakano, Naohiro Ogawa, Rieko Yoshitatsu, Aya Yanagawa-Matsuda, Nako Maishi, Akihiko Kudo, Nanase Okazaki, et al. Nonspecific inflammatory pseudotumor of the maxillary and temporal fossa: a study of seven cases. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 2024
Shintaro Nakano, Machiko Kasai, Keisuke Nakamura, Tsukasa Akasaka, Yasuhiro Yoshida, Shiho Suzuki, Yoichi Ohiro, Akira Hasebe. Epithelial-mesenchymal transition in oral cancer cells induced by prolonged and persistent Fusobacterium nucleatum stimulation. Journal of Oral Biosciences. 2024

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MISC (15)：

足利雄一, 鈴木崇祥, 若林侑輝, 格口渉, 関口珠希, 栗林和代, 本間明宏, 大廣洋一. 頭頸部アルミノックス治療におけるニードルカテーテル穿刺のためのガイドプレートの製作について. 頭頸部癌. 2023. 49. 2. 127-127
長太一, 齋藤紘子, 格口渉, 松沢祐介, 石橋知代子, 小川優, 和田義行, 大廣洋一. 先天性多数歯欠損に対してインプラント治療を行った1例. 日本口腔インプラント学会誌. 2021. 34. 特別号. ポスター-74
栗林和代, 山田珠希, 足利雄一, 大廣洋一, 北村哲也, 鄭漢忠. 当科における舌扁平上皮癌Stage I,II症例の腫瘍の深度と治療成績についての検討. 頭けい部癌. 2017. 43. 2. 192-192
山田珠希, 足利雄一, 小野貢伸, 栗林和代, 大廣洋一, 鄭漢忠. 当科における過去17年間の腺様嚢胞癌症例の臨床的検討. 頭けい部癌. 2017. 43. 2. 252-252
小野寺麻記子, 山崎裕, 秦浩信, 足利雄一, 大廣洋一, 松沢祐介, 小野貢伸, 戸塚靖則, 箕輪和行, 滝波修一, et al. 当施設におけるびまん性硬化性下顎骨骨髄炎の臨床的検討臨床病態について. 日本口腔外科学会雑誌. 2011. 57. Suppl. 137-137

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Books (2)：

Ameloblastoma
University of Indonesia 2019
The Bicon Short Implant: a thirty-year perspective
2018 ISBN:9784781206547

Lectures and oral presentations (89)：

顎関節症・咀嚼筋痛障害の治療で改善した特発性First bite syndromeの1例
(第78回日本口腔科学会学術集会 2024)
COVID-19mRNAワクチン接種後に発症した三叉神経第III枝帯状疱疹の1例
(第50回日本口腔外科学会北日本支部学術集会 2024)
Concept of treatment of oral lesions extending into the maxillary sinus
(The 68th Congress of the Japanese Society of Oral and Maxillofacial Surgeons 2023)
頭頸部アルミノックス治療におけるニードルカテーテル穿刺のためのガイドプレートの製作について
(頭頸部癌 2023)
オトガイ形成術を行った患者における側貌軟組織の変化について
(日本顎変形症学会雑誌 2023)

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Education (2)：

1993 - 1997 Hokkaido University Graduate School of Dental Medicine Clinical Oral Medical Science
1986 - 1992 Hokkaido University School of Dentistry

Professional career (1)：

博士(歯学) (北海道大学)

Work history (12)：

2022/04 - 現在 Oral Pathobiological Science, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University Oral and Maxillofacial Surgery Professor
2016/06 - 2022/03 Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University Oral and Maxillofacial Surgery Associate Professor
2012/06 - 2016/05 Department of Oral and Maxillofacial Surgery Hokkaido University School of Dentistry Associate Professor
2007/04 - 2012/05 Department of Oral and Maxillofacial Surgery, Hokkaido University School of Dentistry Assistant Professor
2003/10 - 2007/03 Hokkaido University Dental Hospital Assistant Professor

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Association Membership(s) (8)：

Japanese Society for Jaw Deformities , 日本口腔インプラント学会 , Japanese Society of Oral Oncology , JAPAN SOCIETY OF CLINICAL ONCOLOGY , JAPAN SOCIETY FOR HEAD AND NECK CANCER , Asian Association of Oral and Maxillofacial Surgeons , JAPANESE SOCIETY OF ORAL AND MAXILLOFACIAL SURGEONS , JAPANESE STOMATOLOGICAL SOCIETY

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