Rchr
J-GLOBAL ID：200901048681343300
Update date: Oct. 15, 2024
Katsuyama Masato
カツヤマ マサト | Katsuyama Masato
Affiliation and department：
Job title：
Associate Professor
Research field (1)：
Pharmacology
Research keywords (5)：
subacute myelo-optic neuropathy (SMON)
, prostaglandin
, NADPH oxidase
, reactive oxygen species (ROS)
, reactive oxygen species
Research theme for competitive and other funds (15)：
- 2020 - 2023 スモンに関する調査研究
- 2019 - 2022 Study on mechanisms of exacerbation of tissue fibrogenesis by NOX4-derived reactive oxygen species
- 2017 - 2020 スモンに関する調査研究
- 2016 - 2019 Clarification of new oxidative signaling involved in tissue fibrogenesis and its application to therapeutic strategy
- 2014 - 2017 スモンに関する調査研究
- 2013 - 2016 A study on signaling pathways associated with NOX4/NADPH oxidase for the development of new antifibrotic drugs
- 2011 - 2014 スモンに関する調査研究
- 2009 - 2010 Study on the molecular basis of the exertion of adverse effects of drugs mediated by regulation of NADPH oxidase activities
- 2008 - 2010 Study on roles of a novel NADPH oxidase isoform in the development of lifestyle related diseases
- 2007 - 2008 A study on the involvement of NADPH oxidase in allergic diseases
- 2005 - 2006 血管平滑筋に発現する種特異的な活性酸素産生酵素の解析
- 2003 - 2004 Paradoxical roles of the aldehyde-metabolizing enzyme, aldose reductase in cardioprotection
- 2003 - 2004 Clarification of the sexual dysfunction by diabetes
- 2002 - 2004 プロスタノイドによる血管平滑筋NADPHオキシダーゼの活性化機構の解明
- 2001 - 2002 Effects of insulin - like growth factor binding protein-3 (IGFBP-3) on diabetes - induced erectile dysfunction (ED)
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Papers (65)：
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Ayana Fujiwara, Keisuke Takemura, Anna Tanaka, Misaki Matsumoto, Masato Katsuyama, Takeshi Okanoue, Kanji Yamaguchi, Yoshito Itoh, Kazumi Iwata, Kikuko Amagase, et al. Carfilzomib shows therapeutic potential for reduction of liver fibrosis by targeting hepatic stellate cell activation. Scientific reports. 2024. 14. 1. 19288-19288
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Misaki Matsumoto, Hikari Sawada, Kazumi Iwata, Masakazu Ibi, Nozomi Asaoka, Masato Katsuyama, Kaori Shintani-Ishida, Hiroshi Ikegaya, Shigehiko Takegami, Atsushi Umemura, et al. Bortezomib is an effective enhancer for chemical probe-dependent superoxide detection. Frontiers in medicine. 2022. 9. 941180-941180
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Hideki Matsumoto, Hideo Sasai, Norio Kawamoto, Masato Katsuyama, Makoto Minamiyama, Satoshi Kuru, Toshiyuki Fukao, Hidenori Ohnishi. Founder genetic variants of ABCC4 and ABCC11 in the Japanese population are not associated with the development of subacute myelo-optico-neuropathy (SMON). Molecular genetics & genomic medicine. 2022. 10. 1. e1845
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Misaki Matsumoto, Junjie Liu, Kazumi Iwata, Masakazu Ibi, Nozomi Asaoka, Xueqing Zhang, Masato Katsuyama, Masaya Matsuda, Takeshi Nabe, Katrin Schröder, et al. NOX1/NADPH oxidase is involved in the LPS-induced exacerbation of collagen-induced arthritis. Journal of Pharmacological Sciences. 2021. 146. 2. 88-97
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Nozomi Asaoka, Masakazu Ibi, Hikari Hatakama, Koki Nagaoka, Kazumi Iwata, Misaki Matsumoto, Masato Katsuyama, Shuji Kaneko, Chihiro Yabe-Nishimura. NOX1/NADPH Oxidase Promotes Synaptic Facilitation Induced by Repeated D2 Receptor Stimulation: Involvement in Behavioral Repetition. The Journal of Neuroscience. 2021. 41. 12. 2780-2794
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MISC (99)：
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勝山 真人. 薬害スモンを引き起こしたクリオキノール(キノホルム)によるノルアドレナリン合成阻害. The Journal of Toxicological Sciences. 2021. 46. Suppl. S71-S71
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勝山 真人. スモン原因解明から50年 キノホルムによる神経毒性発現のメカニズムに関する研究. 国立病院総合医学会講演抄録集. 2020. 74回. SY25-3
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勝山 真人, 矢部 千尋. 薬害スモンを引き起こしたクリオキノールによる遺伝子発現の変化とその意義. 生命科学系学会合同年次大会. 2017. 2017年度. [2P-1119]
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勝山 真人, 矢部 千尋. NADPH oxidaseによる活性酸素種の積極的生成と動物・植物・菌類の高次生命機能 ほ乳類におけるNOX/NADPH oxidaseの生理機能. 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集. 2015. 88回・38回. [2W2-2]
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大島 洋一, 岩田 和実, 松本 みさき, 勝山 真人, 衣斐 督和, 矢部 千尋. 喫煙成分のアミロイドβ蛋白動態への影響 家族性アルツハイマー病細胞モデルを用いた検討. 臨床薬理. 2015. 46. Suppl. S231-S231
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Patents (1)：
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NADPHオキシダーゼの触媒サブユニットNOX1の遺伝子及びその用途
Education (3)：
- 1995 - 1998 Kyoto University Graduate School of Pharmaceutical Sciences
- 1993 - 1995 Kyoto University Graduate School of Pharmaceutical Sciences
- 1989 - 1993 Kyoto University Faculty of Pharmaceutical Sciences
Professional career (2)：
- Ph.D. (Kyoto University)
- Doctor of Pharmaceutical Science
Work history (8)：
- 2012/04 - 現在 Kyoto Prefectural University of Medicine Radioisotope Center Associate Professor
- 2010/04 - 2012/03 Kyoto Prefectural University of Medicine Radioisotope Center Associate Professor
- 2009/04 - 2010/03 Kyoto Prefectural University of Medicine Radioisotope Center Associate Professor
- 2006/04 - 2009/03 Kyoto Prefectural University of Medicine Department of Pharmacology
- 2003/04 - 2006/03 Kyoto Prefectural University of Medicine Department of Pharmacology
- 1999/09 - 2003/03 Kyoto Prefectural University of Medicine Department of Pharmacology
- 1998/10 - 1999/08 National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases Visiting Fellow
- 1998/04 - 1998/09 National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases Special Volunteer
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Association Membership(s) (4)：
The Japanese Society of Toxicology
, 日本分子生物学会
, 日本薬理学会
, The Japanese Biochemical Society
