Rchr
J-GLOBAL ID：200901048854999053
Update date: Sep. 19, 2024
Tsunoda Toshiyuki
ツノダ トシユキ | Tsunoda Toshiyuki
Affiliation and department：
Job title：
Associate Professor
Homepage URL (1)：
https://www.fukuoka-u.ac.jp/fukudaism/research/22/09/17770.html
Research field (4)：
Urology
, Medical biochemistry
, Molecular biology
, Cell biology
Research keywords (5)：
前立腺癌
, 3次元培養
, ZFAT
, KRAS
, 大腸癌
Research theme for competitive and other funds (14)：
- 2023 - 2026 アスペルギルスと細菌の微生物間インタラクション解析による重複感染病態の解明と制御
- 2021 - 2024 Control of KRAS signals in cancer-immune microenvironment
- 2021 - 2024 EmmprinとCD73の結合阻害薬を開発するための基盤研究
- 2020 - 2023 Analysis of inflammation-induced colon cancer development mechanism by adhesive invasive Escherichia coli (AIEC) related molecule
- 2020 - 2023 アスペルギルスと非結核性抗酸菌の細胞間コミュニケーションを介した難治化機序の解明
- 2018 - 2021 Elucidation of in vivo-like signal regulated by mutated KRAS in colorectal cancer spheroid and development of inhibitor.
- 2017 - 2020 Elucidation and clinical application of tumorigenic machinery mediated by proinflammatory factors originating from ulcerative colitis
- 2015 - 2018 Elucidation of the mechanism for regulating microenvironment and cancer development by mutant KRAS
- 2016 - 2017 膵臓癌特異的な微小環境構築能に対する変異KRAS関連シグナル阻害剤の開発
- 2012 - 2016 Comprehensive study on the mechanisms involved in micropapillary or budding type tumor invasion
- 2012 - 2015 Analyse of peripheral secreted microRNA controlled by mutations KRAS in lung cancer.
- 2012 - 2015 Elucidation of the transcription factor Zfat function in the immune system using a conditional knockout mouse model
- 2012 - 2015 Elucidation of Field Effect in Colorectal Cancer with Mutant KRAS
- 2007 - 2009 3次元培養を用いた前立腺癌新規バイオマーカーの検索
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Papers (69)：
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Takanori Kitaguchi, Taichi Matsumoto, Kazumasa Yoshida, Yuriko Hamaguchi, Gen Maruta, Hisanori Maeoka, Shuhei Ishikura, Michitaka Nakano, Yusuke Ishida, Fumihito Hirai, et al. Inhibitory Effect of Pyra-Metho-Carnil on the Differentiation and Maturation of Macrophages in Normal and Cancer Microenvironments. Anticancer research. 2024. 44. 8. 3557-3565
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Mikiko Aoki, Toshiyuki Tsunoda, Kaori Koga, Kazuki Nabeshima, Makoto Hamasaki. MMP-2 Regulation of Emmprin on Tumour Cells and CD73 on Fibroblasts During Tumour-Stromal Interaction. Anticancer research. 2023. 43. 8. 3735-3745
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Kazumasa Yoshida, Kensuke Nishi, Shuhei Ishikura, Taichi Matsumoto, Kazuhiko Nakabayashi, Ryo Yazaki, Takashi Ohshima, Masahiko Suenaga, Senji Shirasawa, Toshiyuki Tsunoda. Inhibitory Effect of Pyra-Metho-Carnil on Cancer Spheroid Growth Through Decrease in Glycolysis-associated Molecules. Anticancer research. 2023. 43. 8. 3717-3726
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Shuhei Ishikura, Kazumasa Yoshida, Toshiyuki Tsunoda, Senji Shirasawa. Death domain-associated protein DAXX regulates noncoding RNA transcription at the centromere through the transcription regulator ZFAT. The Journal of biological chemistry. 2022. 298. 11. 102528-102528
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Tokio Terado, Chul Jang Kim, Akiyo Ushio, Kahori Minami, Yukihiro Tambe, Susumu Kageyama, Akihiro Kawauchi, Toshiyuki Tsunoda, Senji Shirasawa, Hiroyuki Tanaka, et al. Cryptotanshinone suppresses tumorigenesis by inhibiting lipogenesis and promoting reactive oxygen species production in KRAS-activated pancreatic cancer cells. International journal of oncology. 2022. 61. 3
ｍore...
MISC (2)：
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澤田 悠賀, 松川 泰治, 土井 聡, 角田 俊之, 岡本 春奈, 苗村 円佳, 田原 圭一郎, 有川 和沙, 松岡 耕平, 原田 正樹, et al. 新規レスベラトロール誘導体は大腸癌細胞三次元増殖を抑制する. 生命科学系学会合同年次大会. 2017. 2017年度. [3P-1297]
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Toshiyuki Tsunoda, Bungo Furusato, Seiji Naito, Suma Ravulapalli, Albert Dobi, Shiv Srivastava, Junichi Lnokuchi, Darren R. Tyson, David K. Ornstein, Isabell A. Sesterhenn. Comparative analysis of gene expression sigunatures of 3-d culture specific genes and epithelial specific genes from clinicaly localized human prostate normal and cancer specimens. JOURNAL OF UROLOGY. 2008. 179. 4. 424-424
Education (2)：
- 1999 - 2003 Kyushu University Graduate School, Division of Medicine 臓器機能医学系
- 1990 - 1996 Nagasaki University School of Medicine
Professional career (1)：
- M.D.,Ph.D. (Kyushu University)
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