Rchr
J-GLOBAL ID:200901049241691176   Update date: Mar. 15, 2023

Rikinari HANAYAMA,

ハナヤマ リキナリ | Rikinari HANAYAMA,
Affiliation and department:
Other affiliations (1):
Homepage URL  (2): http://immunology.w3.kanazawa-u.ac.jphttp://immunology.w3.kanazawa-u.ac.jp/index2.html
Research field  (3): Medical biochemistry ,  Physiology ,  Immunology
Research keywords  (5): Exosome ,  Extracellular Vesicle ,  Autoinflammation ,  Neurodegeneration ,  Tumor Progression
Research theme for competitive and other funds  (24):
  • 2019 - 2026 WISE Program for Nano-Precision Medicine, Science, and Technology
  • 2023 - 2025 Development of in vivo production technology of engineered exosomes inducing anti-tumor immunity
  • 2022 - 2025 Establishment of a new biomarker using platelets for personalized treatment of pancreatic cancer
  • 2019 - 2024 Development of innovative immunoregulatory methods using designer exosomes
  • 2018 - 2024 Elucidation and control of the interaction of biological responses by microparticles
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Papers (48):
  • Keesiang Lim, Goro Nishide, Elma Sakinatus Sajidah, Tomoyoshi Yamano, Yujia Qiu, Takeshi Yoshida, Akiko Kobayashi, Masaharu Hazawa, Toshio Ando, Rikinari Hanayama, et al. Nanoscopic Assessment of Anti-SARS-CoV-2 Spike Neutralizing Antibody Using High-Speed AFM. Nano Letters. 2023. 23. 2. 619-628
  • Yang Xi, Takeshi Yoshida, Rikinari Hanayama. EVs and Communication. Encyclopedia of Cell Biology. Bradshaw R. eds. (Elsevier). 2023. 2. 390-400
  • Elma Sakinatus Sajidah, Keesiang Lim, Tomoyoshi Yamano, Goro Nishide, Yujia Qiu, Takeshi Yoshida, Hanbo Wang, Akiko Kobayashi, Masaharu Hazawa, Firli R P Dewi, et al. Spatiotemporal tracking of small extracellular vesicle nanotopology in response to physicochemical stresses revealed by HS-AFM. Journal of Extracellular Vesicles. 2022. 11. 11. e12275
  • Xiabing Lyu, Shota Imai, Tomoyoshi Yamano, Rikinari Hanayama. Preventing SARS-CoV-2 Infection Using Anti-spike Nanobody-IFN-β Conjugated Exosomes. Pharmaceutical Research. 2022
  • Takeshi Yoshida, Rikinari Hanayama. TIM4-Affinity Methods Targeting Phosphatidylserine for Isolation or Detection of Extracellular Vesicles. Methods in Molecular Biology (Clifton, N.J.). 2022. 2466. 23-36
more...
MISC (18):
  • Hironori Kawahara, Yasutake Tada, Rikinari Hanayama. Explanation about exosome. Clinical Neuroscience. 2022. 40. 7. 830-833
  • Rikinari Hanayama. EV research at fever pitch. Experimental Medicine. 2021. 39. 20. 2-8
  • Yoshinori Hasebe, Tomoyoshi Yamano, Rikinari Hanayama. Role of exosomes in T cell immune tolerance (Japanese). Clinical Immunology and Allergology. 2021. 75. 5. 565-569
  • Rikinari Hanayama. Trends in exosome research (Japanese). History of Medicine. 2020. 272. 2. 287-291
  • Masahiro Enomoto, Takeshi Yoshida, Rikinari Hanayama. Relationship between exosome release mechanism and cellular stress (Japanese). Clinical Immunology and Allergology. 2019. 72. 1. 43-49
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Patents (7):
  • Compositions that control CAR-T cell activation, hematopoietic stem cell proliferation, and iPS cell differentiation, and their applications
  • Immunoregulatory method, nucleic acid for immunoregulation and use thereof
  • Antigen-presenting extracellular vesicles
  • Prognostic or assisted prognostic methods for bone tumors
  • Compounds for promoting the secretion of extracellular vesicles
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Books (11):
  • Experimental Medicine: New Macrophage
    Yodosha 2022
  • Experimental Medicine: Biology of EVs
    Yodosha 2021
  • Experimental Medicine: New Generation Flow Cytometry
    Yodosha 2021
  • JB Special Issue-Medical chemistry of extracellular vesicles
    Oxford Academic 2021
  • An overview report on research and development in the field of life sciences and clinical medicine (2019)
    Japan Science and Technology Agency (JST) 2019
more...
Lectures and oral presentations  (106):
  • The 48th Annual Meeting of Japanese Society for Biomedical Mass Spectrometry, Nagoya
    (2023)
  • Meiwafosis Webinar
    (2023)
  • ISEV2023 Platinum Sponsored Session, Seattle, USA
    (2023)
  • Graduate School Special Lecture, Wakayama Medical University, Wakayama
    (2023)
  • Biocompare Webinar
    (2023)
more...
Education (3):
  • 2000 - 2004 Ph.D, Osaka University (Advisor: Prof. Shigekazu Nagata)
  • 1993 - 1999 MD, Osaka University
  • 1990 - 1993 Takatsuki High School
Professional career (1):
  • MD, PhD (Osaka University)
Work history (12):
  • 2019 - 現在 Coordinator, WISE Program for Nano-Precision Medicine, Science, and Technology, Kanazawa University
  • 2018 - 現在 JST CREST Investigator
  • 2017 - 現在 Professor, WPI Nano Life Science Institute, Kanazawa University
  • 2015 - 現在 Professor, Department of Immunology, Graduate School of Medical Sciences, Kanazawa University
  • 2015 - 2017 MEXT KAKENHI Program Officer
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Committee career (10):
  • 2022 - 現在 Kanazawa University Member, Office of Reform and Research Strategy
  • 2022 - 現在 Advisory Committee Member, Institute for Protein Research, Osaka University
  • 2021 - 現在 Vice Chairman, The Science Board Subcommittee, PMDA
  • 2020 - 現在 Steering Committee Member, JST FOREST Program
  • 2019 - 現在 Advisor, FUJIFILM
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Awards (9):
  • 2021 - JB Reviewer Award
  • 2019 - Kanazawa University Merit Award
  • 2014 - Osaka University Presidential Award
  • 2012 - Astellas Biomedical Award
  • 2011 - HFSP Career Development Award
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Association Membership(s) (4):
International Society for Extracellular Vesicles (ISEV) ,  The Molecular Biology Society of Japan ,  The Japanese Society for Immunology ,  The Japanese Biochemical Society
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