Sohara Eisei

ソハラエイセイ | Sohara Eisei

Affiliation and department：
Job title： Associate Professor

Research field (3)： Nephrology , Genetics , Physiology

Research theme for competitive and other funds (21)：

2024 - 2028 エネルギー感知機構の破綻による慢性腎臓病の線維化進行機序解明と治療法開発
2024 - 2028 ストレスと臓器線維化をつなぐエネルギー恒常性機構破綻の病態解明と臨床応用
2025 - 2027 Elucidating the Pathophysiology of Nephronophthisis, a Hereditary Renal Fibrotic Disease, and iPSC-based Drug Discovery
2024 - 2027 ysregulation of AMPK signal, as the target for the renal epithelial damage in chronic kidney disease
2022 - 2025 腎オルガノイドを用いたForward Geneticによる腎線維化制御機構の探索

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Papers (444)：

Shunsuke Inaba, Takanori Hasegawa, Yuta Nakano, Shotaro Naito, Rena Suzukawa, Takaaki Koide, Hisateru Sekiya, Hisazumi Matsuki, Tamami Fujiki, Hiroaki Kikuchi, et al. Circulating Extracellular Vesicle MicroRNAs as Predictive Biomarkers for Kidney and Cardiovascular Events. Journal of the American Heart Association. 2025
Nobuhisa Morimoto, Hiroaki Kikuchi, Yukiko Nishihama, Eisei Sohara, Shinichi Uchida, Shoji F Nakayama. Association between urinary organophosphate pesticide metabolites and blood lipid levels in US children. Ecotoxicology and environmental safety. 2025. 306. 119330-119330
Nobuhisa Morimoto, Shintaro Mandai, Tamami Fujiki, Fumiaki Ando, Takayasu Mori, Koichiro Susa, Shotaro Naito, Eisei Sohara, Tatsuhiko Anzai, Kunihiko Takahashi, et al. Association between serum bicarbonate and low mid-upper arm circumference in patients with non-dialysis-dependent chronic kidney disease: A cross-sectional study. Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition. 2025
Yuki Nakao, Junko Kunieda, Towako Taguchi, Yuki Tanaka, Soichiro Iimori, Fumiaki Ando, Shintaro Mandai, Koichiro Susa, Takayasu Mori, Shotaro Naito, et al. Delayed Therapeutic Response to Oral Corticosteroids and Rituximab Leading to Dialysis Independence in a Patient with Treatment-resistant C3 Glomerulonephritis. Internal medicine (Tokyo, Japan). 2025
Yuki Nakao, Makiko Mori, Yuta Sekiguchi, Iori Morita, Ryota Shindoh, Shintaro Mandai, Tamami Fujiki, Hiroaki Kikuchi, Fumiaki Ando, Koichiro Susa, et al. A Human Kidney Tubuloid Model of Repeated Cisplatin-Induced Cellular Senescence and Fibrosis for Drug Screening. Advanced healthcare materials. 2025. e01795

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MISC (180)：

原悠, 藤田雅子, 森本靖久, 森崇寧, 須佐紘一郎, 飯盛聡一郎, 内藤省太郎, 蘇原映誠, 内田信一. 腎臓超音波画像からAIが推定した形態学的老化度は腎予後を独立して予測する. 日本腎・血液浄化AI学会学術集会・総会プログラム・抄録集. 2025. 5回. 33-33
眞部俊, 宮野姿子, 潮雄介, 片岡浩史, 森崇寧, 蘇原映誠, 星野純一. 両腎の多発微小嚢胞からADPKD-DNAJB11と診断した一家系. 日本腎臓学会誌. 2025. 67. 6-E. 779-779
鹿又義貴, 藤丸拓也, 前遥貴, 伊藤雄伍, 長浜正彦, 瀧史香, 千賀宗子, 蘇原映誠, 内田信一, 長田道夫, et al. 高齢発症・治療抵抗性を示したProliferative Glomerulonephritis with Monoclonal IgG Deposits(PGNMID)の一例. 日本腎臓学会誌. 2025. 67. 6-E. 813-813
田中彩之, 眞部俊, 須山真弓子, 関桃子, 井藤奈央子, 片岡浩史, 種田積子, 杉浦秀和, 森崇寧, 蘇原映誠, et al. NPHP3およびNPHP4変異の二遺伝子遺伝によるネフロン癆の一例. 日本腎臓学会誌. 2025. 67. 6-E. 816-816
梶原佳子, 豊原敬文, 榎亮, 中里彰彦, 渡邉駿, 菊地晃一, 吉田舞, 牧野塁, 大江佑治, 岡本好司, et al. FSGSを呈し,COL4A4変異を認めた成人発症難治性ネフローゼの一例. 日本腎臓学会誌. 2025. 67. 6-E. 827-827

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Patents (3)：

ネフロン癆の処置に用いるための医薬組成物
ネフロン癆の処置に用いるための医薬組成物
慢性腎臓病の検査方法

Lectures and oral presentations (78)：

Advances in the Diagnosis and Clinical Strategy for Inherited Kidney Diseases.
(Taiwan Defence Medical University Medical Seminer 2025)
多発性嚢胞腎の診断と治療 ~遺伝子から新規治療薬候補まで〜
(多発性嚢胞腎患者会講演会 2025 2025)
慢性腎臓病におけるエネルギー感知障害
(第68回日本腎臓学会学術総会ワークショップ 2025)
Trends in Diagnosing Genetic Kidney Diseases.
(World Congress of Nephrology (International Society of Nephrology), ニューデリー、インド 2025)
Genetic Diagnosis of Adult Hemodialysis Patients With Unknown Etiology.
(日本透析医学会日本透析医学会賞受賞講演 2024)

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Work history (8)：

2024/10 - 現在東京科学大学医歯学総合研究科腎臓内科学准教授、診療科長
2024/04 - 現在東京科学大学病院稀少疾患先端医療センターセンター長
2024/04 - 2024/09 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences Systemic Organ Regulation Nephrology Director
2015/11 - 2024/03 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences Systemic Organ Regulation Nephrology Associate Professor
2013/04 - 2015/10 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences Systemic Organ Regulation Nephrology Junior Associate Professor

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Awards (16)：

2026/03 - 令和7年度手島精一記念研究賞(研究論文賞)
2025/06 - 日本透析医学会日本透析医学会賞(木本賞) Genetic diagnosis of adult hemodialysis patients with unknown etiology
2017/10 - 蘇原映誠第40回日本高血圧学会総会第7回学術賞
2016/10 - 東京医科歯科大学優秀研究賞
2016/08 - 平成28年度学長裁量優秀若手研究者奨励賞

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