Rchr
J-GLOBAL ID：200901049946216680   Update date: Nov. 14, 2024

Murayama Kazutaka

ムラヤマ カズタカ | Murayama Kazutaka
Affiliation and department：
Tohoku University Graduate School of Biomedical Engineering Department of Biomedical Engineering Biomedical Measurements and Diagnostics Biomedical Supramolecular Analysis

About Tohoku University Graduate School of Biomedical Engineering Department of Biomedical Engineering Biomedical Measurements and Diagnostics Biomedical Supramolecular Analysis


Job title： Associate Professor
Homepage URL  (2)： http://db.tohoku.ac.jp/whois/detail/3322e369ace9c5c513f6ed491e5b6b80.html ,  http://db.tohoku.ac.jp/whois/e_detail/3322e369ace9c5c513f6ed491e5b6b80.html
Research field  (1)： Structural biochemistry
Research keywords  (3)： 生物物理化学 ,  生体高分子 ,  構造解析
Research theme for competitive and other funds  (10)：
  • 2024 - 2027 Contribution of post-proteolytic pathways to skeletal muscle volume
  • 2021 - 2024 The role of post-proteolytic aminopeptidases in skeletal muscle homeostasis
  • 2018 - 2022 Development of a basis for establishing the ultimate transplantation medicine that does not require the administration of immunosuppressive drugs
  • 2018 - 2021 Contribution of protein recycling system for the maintenance of skeletal muscle mass
  • 2015 - 2019 Establishment of next-generation diabetes treatment by construction of tailor-made cell isolation system
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Papers (144)：
  • Kazutaka Murayama, Miyuki Kato-Murayama, Toshiaki Hosaka, Toshio Kitamura, Shigeyuki Yokoyama, Mikako Shirouzu. Structural basis for the effects of Ser387 phosphorylation of MgcRacGAP on its GTPase-activating activities for CDC42 and RHOA. Journal of structural biology. 2024. 108151-108151
  • Hironori Hayashi, Erika Saijo, Kazushige Hirata, Shumei Murakami, Haruka Okuda, Eiichi N Kodama, Kazuya Hasegawa, Kazutaka Murayama. SHIN-2 exerts potent activity against VanA-type vancomycin-resistant Enterococcus faecium in vitro by stabilizing the active site loop of serine hydroxymethyltransferase. Archives of biochemistry and biophysics. 2024. 110160-110160
  • Shin-ichiro Hattori, Haydar Bulut, Hironori Hayashi, Naoki Kishimoto, Nobutoki Takamune, Kazuya Hasegawa, Yuri Furusawa, Seiya Yamayoshi, Kazutaka Murayama, Hirokazu Tamamura, et al. Structural and virologic mechanism of the emergence of resistance to M pro inhibitors in SARS-CoV-2. Proceedings of the National Academy of Sciences. 2024. 121. 37
  • Kazutaka Murayama, Toshiaki Hosaka, Mikako Shirouzu, Daisuke Sugimori. Structure of a phosphodiesterase from Streptomyces sanglieri with a novel C-terminal domain. Biochemical and biophysical research communications. 2024. 708. 149784-149784
  • Kazutaka Murayama, Miyuki Kato-Murayama, Toshiaki Hosaka, Naoko Okitsu, Yoshikazu Tanaka, Mikako Shirouzu. Molecular basis of ligand recognition specificity of flavone glucosyltransferases in Nemophila menziesii. Archives of biochemistry and biophysics. 2024. 753. 109926-109926
ｍore...
MISC (63)：
  • 長名 シオン, 北嶋 康雄, 鈴木 直輝, 高田 拓明, 村山 和隆, 永富 良一. アミノペプチダーゼによる筋分化制御メカニズムの解明. 日本筋学会学術集会プログラム・抄録集. 2022. 8回. 144-144
  • Mutsuko Kukimoto-Niino, Kentaro Ihara, Kazutaka Murayama, Mikako Shirouzu. Structural insights into the small GTPase specificity of the DOCK guanine nucleotide exchange factors. Current Opinion in Structural Biology. 2021. 71. 249-258
  • Shion Osana, Kazutaka Murayama, Ryoichi Nagatomi. The impact of intracellular aminopeptidase on C2C12 myoblast proliferation and differentiation. Biochemical and biophysical research communications. 2020. 524. 3. 608-613
  • Shion Osana, Kazutaka Murayama, Naoki Suzuki, Hiroaki Takada, Takahiro Kubota, Ryoichi Nagatomi. Inhibition of leucine aminopeptidase affects myocyte proliferation and differentiation. FASEB JOURNAL. 2020. 34
  • 河原光希, 小山貴之, 酒瀬川信一, 村山和隆, 杉森大助, 杉森大助. コリン型リゾプラズマローゲン特異的ホスホリパーゼDの基質認識におけるPhe211およびTyr258の役割. 日本生物工学会大会講演要旨集. 2018. 70th. 200-200
ｍore...
Books (2)：
  • Metal Ions in Life Sciences vol.10
    Springer Science 2011
  • 遺伝子工学集中マスター
    羊土社 2006
Education (1)：
  • - 1998 Toyohashi University of Technology Graduate School, Division of Engineering 機能材料工学
Professional career (1)：
  • Engineering (Toyohashi University of Technology)
Work history (4)：
  • 2008/04 - Graduate School of Biomedical Engineering, Tohoku University Associate Professor
  • 2005/01 - 2008/03 東北大学先進医工学研究機構
  • 2001/09 - 2004/12 理化学研究所ゲノム科学総合研究センター
  • 1998/04 - 2001/08 Free University of Berlin
Association Membership(s) (3)：
日本生物物理学会 ,  蛋白質科学会 ,  日本結晶学会
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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