J-GLOBAL ID:200901050165331457   Update date: May. 18, 2020

Takaya Akiko

タカヤ アキコ | Takaya Akiko
Affiliation and department:
Job title: Chiba University
Research field  (1): Bacteriology
Research theme for competitive and other funds  (11):
  • 2018 - 2021 Functional analysis of lncRNAs regulating immune response
  • 2015 - 2018 Study of long noncoding RNAs in immune response
  • 2015 - 2017 Identification and development of anti-persister compounds as a new class of antibiotics to treat chronic infection
  • 2013 - 2016 Studies on Salmonella infection and host response based on the interaction between effector and its host target
  • 2013 - 2015 Studies on the next-generation antimicrobial agents by high-through-put screening of small-molecule compounds inhibiting bacterial effector
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Papers (7):
  • Christian Männe, Akiko Takaya, Yuzuru Yamasaki, Mathias Mursell, Shintaro Hojyo, Tsung-Yen Wu, Jana Sarkander, Mairi A McGrath, Rebecca Cornelis, Stefanie Hahne, Qingyu Cheng, Tadafumi Kawamoto, Falk Hiepe, Stefan H E Kaufmann, Tomoko Yamamoto, Andreas Radbruch, Koji Tokoyoda. Salmonella SiiE prevents an efficient humoral immune memory by interfering with IgG+ plasma cell persistence in the bone marrow. Proceedings of the National Academy of Sciences of the United States of America. 2019. 116. 15. 7425-7430
  • Akiko Takaya, Hikari Takeda, Shogo Tashiro, Hiroto Kawashima, Tomoko Yamamoto. Chaperone-mediated secretion switching from early to middle substrates in the type III secretion system encoded by Salmonella pathogenicity island 2. The Journal of biological chemistry. 2019. 294. 10. 3783-3793
  • Akiko Takaya, Tomoko Yamamoto, Koji Tokoyoda. Humoral Immunity vs. Salmonella. Frontiers in immunology. 2019. 10. 3155-3155
  • Takeshi Shimizu, Yukako Fujinaga, Akiko Takaya, Hiroshi Ashida, Toshio Kodama, Masanori Hatakeyama. [Molecular targets of bacterial effectors and toxins that underlie vulnerability to diseases]. Nihon saikingaku zasshi. Japanese journal of bacteriology. 2015. 70. 2. 319-28
  • Hang’ombe BM, Isogai E, Mubita C, Isogai N, Silungwe M, Chisenga C, Moonga L, Mulenga E, Yabe J, Takaya A, Yamamoto T, Kurebayashi Y, Isogai H. Detection of invA, spiC, sipC, invF, and hilA in Salmonella Isolated from beef and poultry by dot blot hybridization in Zambia. Int J Appl Res Vet Med. 2008. 6. 1. 1-6
MISC (1):
  • 松井 真理, 高屋 明子, 山本 友子. サルモネラのDnaKシャペロンによるHilA発現制御機構. 日本細菌学雑誌. 2007. 62. 1. 120-120
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