Takaya Akiko

タカヤアキコ | Takaya Akiko

Affiliation and department：
Job title： Associate professor

Research field (1)： Bacteriology

Research keywords (3)：シャペロン・プロテアーゼ , 薬剤耐性 , 細菌感染症

Research theme for competitive and other funds (7)：

2006 - 2007 6型蛋白分泌装置OMVを利用した0157コンポーネントワクチン開発に関する研究
2005 - 2006 Expression control mechanisms of LEE pathogenic factors by AAA proteases in Enterohaemorrhagic and Enteropathogenic Eschericha coli
2004 - 2006 Lonプロテアーゼによる緑膿菌のタイプIII病原蛋白分泌機構の制御に関する研究
2004 - 2005 Molecular mechanisms of intracellular growth of Salmonella
2003 - 2004 Regulatory mechanisms of type III secretion system by molecular chaperones and proteases in Salmonella enterica serovar Typhimurium.

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Papers (64)：

Yasumasa Hara, Ayaka Nakamura, Teruhisa Manome, Akiko Takaya, Hiroki Takahashi, Sayaka Ban, Takashi Yaguchi, Masami Ishibashi. A new diterpenoid, carneadiol, isolated from Nocardia carnea IFM 12324. Journal of Natural Medicines. 2025
Yuriko Yamazaki, Tomoka Ito, Seitaro Nakagawa, Takashi Sugihira, Chinami Kurita-Tachibana, Amer E. Villaruz, Kensuke Ishiguro, Barbora Salcman, Shuo Li, Sanami Takada, et al. Altered genomic methylation promotes Staphylococcus aureus persistence in hospital environment. Nature Communications. 2024. 15. 1
Junpei Yamaguchi, Teruhisa Manome, Yasumasa Hara, Yuriko Yamazaki, Yuumi Nakamura, Masami Ishibashi, Akiko Takaya. Physalin H, physalin B, and isophysalin B suppress the quorum-sensing function of Staphylococcus aureus by binding to AgrA. Frontiers in Pharmacology. 2024. 15
Kazuki Fujii, Itsuki Iwata, Akiko Takaya, Masami Ishibashi, Yasumasa Hara. New biflavonoids isolated from Xylia kerrii leaves extract with selective cytotoxicity against MH7A human rheumatoid arthritis synovial fibroblast cells. Journal of Natural Medicines. 2024. 78. 3. 732-740
Reika Aoyama, Seitaro Nakagawa, Yoko Ichikawa, Naohiro Inohara, Yuriko Yamazaki, Tomoka Ito, Takashi Sugihira, Michihiro Kono, Masashi Akiyama, Hiroki Takahashi, et al. Neonatal skin dysbiosis to infantile atopic dermatitis: Mitigating effects of skin care. Allergy. 2024

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MISC (93)：

浅沼朋花, 原康雅, 原康雅, 千葉まれの, 高屋明子, 高屋明子, 高屋明子, 石橋正己, 石橋正己. Search for natural products with anti-fungal activity from co-culture of actinomycates. 日本薬学会年会要旨集(Web). 2023. 143rd
山中夏樹, 山口隼平, 高橋弘喜, 高橋弘喜, 原康雅, 原康雅, 石橋正己, 石橋正己, 高屋明子, 高屋明子, et al. The alternative mechanism of carbapenem tolerance in non-carbapenemase-producing Klebsiella. 日本薬学会年会要旨集(Web). 2023. 143rd
Search for new natural products from Nocardia carnea IFM 12324 and biosynthetic gene analysis for an isolated compound. 日本薬学会年会要旨集(Web). 2023. 143rd
Physalin H inhibits expression of the agr quorum sensing system without suppressing Staphylococcus aureus growth. 日本薬学会年会要旨集(Web). 2023. 143rd
Search for natural products from Xylia kerri with cytotoxicity for rheumatoid fibroblast-like synoviocytes. 日本薬学会年会要旨集(Web). 2023. 143rd

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