Kasai Hitoshi

カサイヒトシ | Kasai Hitoshi

Affiliation and department：
Job title： Professor
Homepage URL (2)： http://www2.tagen.tohoku.ac.jp/lab/kasai/ , http://www2.tagen.tohoku.ac.jp/lab/kasai/english/

Research field (4)： Crystal engineering , Applied materials , Structural and functional materials , Functional solid-state chemistry

Research theme for competitive and other funds (11)：

2022 - 2026 がん細胞特有の刺激に応答し薬物を放出する新規抗がん薬ナノ粒子の開発
2021 - 2025 Knowledge-driven Nanodrug design through understanding of a role of Phase-separated condensate in chemotherapy using Single-Cell endoscopy
2022 - 2024 分子技術を駆使したSN-38二量体設計と新規抗がん用ナノ薬剤の創出
2021 - 2024 瘢痕化定量技術と薬剤ナノ粒子化による組織移行性の高い濾過胞瘢痕抑制薬の開発
2019 - 2022 Development of anti-cancer nanodrugs with high drug loading capacity and dispersion stability by surface modification

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Papers (224)：

Keitaro Yamauchi, Hirotaka Nakatsuji, Takaaki Kamishima, Yoshitaka Koseki, Masaki Kubo, Hitoshi Kasai. Combined substituent number utilized machine learning for the development of antimicrobial agent. Scientific Reports. 2024. 14. 1
Yutaka Maeda, Yasuhiro Suzuki, Yui Konno, Pei Zhao, Nobuhiro Kikuchi, Michio Yamada, Masaya Mitsuishi, Anh T.N. Dao, Hitoshi Kasai, Masahiro Ehara. Selective emergence of photoluminescence at telecommunication wavelengths from cyclic perfluoroalkylated carbon nanotubes. Communications Chemistry. 2023. 6. 1
Kiyotaka Maruoka, Ryuju Suzuki, Takaaki Kamishima, Yoshitaka Koseki, Anh Thi Ngoc Dao, Toshihiro Murafuji, Hitoshi Kasai. Total Synthesis of Azulene Derivative, a Blue Pigment Isolated from Lactarius indigo, and Colorant Application of Its Aqueous Dispersion. Journal of Agricultural and Food Chemistry. 2023
Grasianto, Mao Fukuyama, Motohiro Kasuya, Derrick M. Mott, Yoshitaka Koseki, Hitoshi Kasai, Akihide Hibara. Sensitive and simple multi-ion detection using organic nanocrystal enrichment in paper analytical devices. Analytica Chimica Acta. 2023. 341451-341451
Qiang Zhang, Taku Murasugi, Kotomi Watanabe, Han Wen, Ya Tian, Monica Ricci, Susana Rocha, Tomoko Inose, Hitoshi Kasai, Farsai Taemaitree, et al. Selective Detection of Intracellular Drug Metabolism by Metal-Organic Framework-Coated Plasmonic Nanowire. Advanced Optical Materials. 2023

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MISC (72)：

Farsai Taemaitree, Beatrice Fortuni, Yoshitaka Koseki, Eduard Fron, Susana Rocha, Johan Hofkens, Hiroshi Uji-i, Tomoko Inose, Hitoshi Kasai. FRET-based intracellular investigation of nanoprodrugs toward highly efficient anticancer drug delivery (vol 12, pg 16710, 2020). NANOSCALE. 2020. 12. 42. 21951-21951
Nano-prodrug: The dynamics of novel anticancer drug delivery system. 2020. 52. 13. 47-51
Nano-Prodrugs for Anti-cancer Drug Delivery. The Bulletin of the Society of Nano Science and Technology. 2020. 19. 1. 15-20
Anh Dao, Hitoshi Kasai. Facile preparation of Au/Silk nanoparticles as a multifunctional drug delivery system. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2019. 258
小関良卓, 笠井均. 緑内障治療薬ブリンゾラミド誘導体のナノ粒子作製と薬効評価. 化学工業. 2018. 69. 4. 304-308

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Patents (40)：

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Books (31)：

新規モダリティ医薬品にための新しいDDS技術と制剤化」抜刷
技術情報協会 2023
ナノ・プロドラッグのin vivoにおける薬理効果
技術情報協会 2017
最新マイクロ波エネルギーと応用技術
株式会社産業技術サービスセンター 2014
Fabrication of Polyimide Porous Nanostructures for Low-k Materials
Nanocrystal, ed., by Marc J.M. Abadie, In Tech 2012
ポリイミドナノ粒子による次世代low-k膜生成, Vol.4
2012

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Lectures and oral presentations (109)：

リポソームにより被覆したナノ・プロドラッグのがん細胞内/外挙動の解析
(第45回日本バイオマテリアル学会大会 2023)
Fabrication of zinc complex nanoparticles for development of high-performance scintillator
(2023)
Fabrication of an acrolein-responsive nano-prodrugs for anticancer therapy
(International Symposium for the 80th Anniversary of the Tohoku Branch of the Chemical Society of Japan 2023)
Fabrication and drug release properties of prodrug nanopaticles with high cancer selectivity
(International Symposium for the 80th Anniversary of the Tohoku Branch of the Chemical Society of Japan 2023)
Total synthesis of azulene derivative, a blue pigment in an edible mushroom
(International Symposium for the 80th Anniversary of the Tohoku Branch of the Chemical Society of Japan 2023)

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Professional career (1)：

Association Membership(s) (4)：

繊維学会 , 応用物理学会 , 日本化学会 , 高分子学会

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