Kasai Hitoshi

カサイヒトシ | Kasai Hitoshi

Affiliation and department：
Job title： Professor
Homepage URL (2)： http://www2.tagen.tohoku.ac.jp/lab/kasai/ , http://www2.tagen.tohoku.ac.jp/lab/kasai/english/

Research field (4)： Crystal engineering , Applied materials , Structural and functional materials , Functional solid-state chemistry

Research theme for competitive and other funds (11)：

2022 - 2026 がん細胞特有の刺激に応答し薬物を放出する新規抗がん薬ナノ粒子の開発
2021 - 2025 Knowledge-driven Nanodrug design through understanding of a role of Phase-separated condensate in chemotherapy using Single-Cell endoscopy
2022 - 2024 分子技術を駆使したSN-38二量体設計と新規抗がん用ナノ薬剤の創出
2021 - 2024 瘢痕化定量技術と薬剤ナノ粒子化による組織移行性の高い濾過胞瘢痕抑制薬の開発
2019 - 2022 Development of anti-cancer nanodrugs with high drug loading capacity and dispersion stability by surface modification

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Papers (251)：

Mohammad Oves, Ryuju Suzuki, Hirotaka Nakatsuji, Yoshitaka Koseki, Sanjay Kumar, Kouki Oka, Hitoshi Kasai. Photodynamic antimicrobial activity of polydiacetylene crystal nanostructure against E. coli. MRS Communications. 2024
Sanjay Kumar, Yoshitaka Koseki, Takaaki Kamishima, Hitoshi Kasai. A concise synthesis of methyl dihydrojasmonate and methyl (5-methylidene-4-oxocyclopent-2-en-1-yl)acetate from D-glucose. Mendeleev Communications. 2024. 34. 4. 528-530
Hu-Jun Lee, Daisuke Hanyu, Anh Thi Ngoc Dao, Hitoshi Kasai, Minori Suzuki, Hiroshi Yabu, Hisayuki Nakatani, Kenji Kaneko. Controlling the composition and nanostructure of Au@Ag-Pt core@multi-shell nanoparticles prepared by co-reduction method. Materials Today Chemistry. 2024. 38. 102132-102132
Yoshitaka Koseki, Keita Tanita, Motofumi Nakamura, Aki Shibata, Kiyotaka Maruoka, Takaaki Kamishima, Hitoshi Kasai. Fabrication of carrier-free heterodimeric nano-prodrugs with podophyllotoxin and SN-38 for a co-delivery system. Molecular Crystals and Liquid Crystals. 2024. 1-7
Keitaro Yamauchi, Hirotaka Nakatsuji, Takaaki Kamishima, Yoshitaka Koseki, Masaki Kubo, Hitoshi Kasai. Combined substituent number utilized machine learning for the development of antimicrobial agent. Scientific Reports. 2024. 14. 1

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MISC (73)：

中辻博貴, 神島尭明, 野中利之, 小関良卓, 笠井均. Catalyst-free conversion of 2,5-bis (hydroxymethyl) furan into cyclopentenone derivatives in water. 日本化学会春季年会講演予稿集(Web). 2022. 102nd
Farsai Taemaitree, Beatrice Fortuni, Yoshitaka Koseki, Eduard Fron, Susana Rocha, Johan Hofkens, Hiroshi Uji-i, Tomoko Inose, Hitoshi Kasai. FRET-based intracellular investigation of nanoprodrugs toward highly efficient anticancer drug delivery (vol 12, pg 16710, 2020). NANOSCALE. 2020. 12. 42. 21951-21951
Nano-prodrug: The dynamics of novel anticancer drug delivery system. 2020. 52. 13. 47-51
Nano-Prodrugs for Anti-cancer Drug Delivery. The Bulletin of the Society of Nano Science and Technology. 2020. 19. 1. 15-20
Anh Dao, Hitoshi Kasai. Facile preparation of Au/Silk nanoparticles as a multifunctional drug delivery system. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2019. 258

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Patents (40)：

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Books (31)：

新規モダリティ医薬品にための新しいDDS技術と制剤化」抜刷
技術情報協会 2023
ナノ・プロドラッグのin vivoにおける薬理効果
技術情報協会 2017
最新マイクロ波エネルギーと応用技術
株式会社産業技術サービスセンター 2014
Fabrication of Polyimide Porous Nanostructures for Low-k Materials
Nanocrystal, ed., by Marc J.M. Abadie, In Tech 2012
ポリイミドナノ粒子による次世代low-k膜生成, Vol.4
2012

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Lectures and oral presentations (109)：

リポソームにより被覆したナノ・プロドラッグのがん細胞内/外挙動の解析
(第45回日本バイオマテリアル学会大会 2023)
Fabrication of zinc complex nanoparticles for development of high-performance scintillator
(2023)
Fabrication of an acrolein-responsive nano-prodrugs for anticancer therapy
(International Symposium for the 80th Anniversary of the Tohoku Branch of the Chemical Society of Japan 2023)
Fabrication and drug release properties of prodrug nanopaticles with high cancer selectivity
(International Symposium for the 80th Anniversary of the Tohoku Branch of the Chemical Society of Japan 2023)
Total synthesis of azulene derivative, a blue pigment in an edible mushroom
(International Symposium for the 80th Anniversary of the Tohoku Branch of the Chemical Society of Japan 2023)

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Professional career (1)：

Association Membership(s) (4)：

繊維学会 , 応用物理学会 , 日本化学会 , 高分子学会

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