Rchr
J-GLOBAL ID:200901050872561280   Update date: Nov. 07, 2024

Kakuta Shigeru

カクタ シゲル | Kakuta Shigeru
Affiliation and department:
Other affiliations (2):
Homepage URL  (1): http://www.vm.a.u-tokyo.ac.jp/jitsudo/
Research field  (3): Laboratory animal science ,  Immunology ,  Animal production science
Research keywords  (9): Propolis ,  疾患モデル ,  発生工学 ,  発がん ,  糖鎖認識分子 ,  サイトカイン ,  Molecular Genetics ,  Tumorigenesis ,  Cytokine
Research theme for competitive and other funds  (59):
  • 2024 - 2027 Elucidation of a novel oral immune system led by taste cells
  • 2023 - 2026 細菌の定着性強化に向けた基盤技術創製ーバイオフィルム形成に学ぶー
  • 2022 - 2026 Investigations of the relationship between antitumor immunity and chemotherapy resistance focusing on heterogeneity in tumor tissues
  • 2023 - 2025 Mechanisms of autoimmunity induced by excess IL-1 signaling
  • 2022 - 2025 Analysis of mammalian survival mechanism under stressed temperature using novel mutant-HSF1 knock-in mice
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Papers (87):
  • Hiromi Miura, Ayaka Nakamura, Aki Kurosaki, Ai Kotani, Masaru Motojima, Keiko Tanaka, Shigeru Kakuta, Sanae Ogiwara, Yuhsuke Ohmi, Hirotaka Komaba, et al. Targeted insertion of conditional expression cassettes into the mouse genome using the modified i-PITT. BMC Genomics. 2024. 25. 1
  • Atsushi Minami, Takehiro Asai, Tsuyoshi Tachibana, Yu Tanaka, Mitsuyuki Nakajima, Shiori Tamura, Morihiro Nakazawa, Yoshiharu Tsuru, Yoichi Fujiyama, Yoh-Ichi Tagawa, et al. Establishment of the improved colonization of Escherichia coli laboratory strain in the intestine mediated by single gene deletion. Biochemical and biophysical research communications. 2024. 734. 150448-150448
  • Masahiro Sato, Ayaka Nakamura, Marie Sekiguchi, Takashi Matsuwaki, Hiromi Miura, Channabasavaiah B Gurumurthy, Shigeru Kakuta, Masato Ohtsuka. Improved Genome Editing via Oviductal Nucleic Acids Delivery (i-GONAD): Protocol Steps and Additional Notes. Methods in molecular biology (Clifton, N.J.). 2023. 2631. 325-340
  • Yasuko Tokunaga, Ken-Ichiro Otsuyama, Shigeru Kakuta, Naoki Hayashida. Heat Shock Transcription Factor 2 Is Significantly Involved in Neurodegenerative Diseases, Inflammatory Bowel Disease, Cancer, Male Infertility, and Fetal Alcohol Spectrum Disorder: The Novel Mechanisms of Several Severe Diseases. International journal of molecular sciences. 2022. 23. 22
  • Yulan Tang, Chen Wang, Mark Joseph M Desamero, Mun Keong Kok, James Kenn Chambers, Kazuyuki Uchida, Yuri Kominami, Hideki Ushio, Cleofas Cervancia, Maria Amelita Estacio, et al. The Philippines stingless bee propolis promotes hair growth through activation of Wnt/β-catenin signaling pathway. Experimental animals. 2022. 72. 1. 132-139
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MISC (128):
  • 橘毅, 田中優, 中島満幸, 浅井健宏, 南篤, 田川陽一, 水流功春, 藤井渉, 藤井渉, 久和茂, et al. マウスを用いた定着性改変大腸菌の腸管内分布の解析. 日本実験動物学会総会講演要旨集(Web). 2024. 71st
  • 浅井健宏, 浅井健宏, 南篤, 水流功春, 関口茉莉恵, 島野翔太郎, 栃内亮太, 富安博隆, チェンバーズ ジェームズ, 内田和幸, et al. 非古典的な翻訳開始機構は周産期における母体循環器系機能の維持に寄与する. 日本実験動物学会総会講演要旨集(Web). 2024. 71st
  • MANIWANG Jonna Rose, 湯玉蘭, 湯玉蘭, 王辰, 王辰, DESAMERO Mark Joseph, DESAMERO Mark Joseph, DESAMERO Mark Joseph, 藤井渉, 藤井渉, et al. マウスを用いたハリナシバチ由来プロポリスの抗癌剤誘導脱毛に対する有用性の検討. 日本実験動物学会総会講演要旨集(Web). 2024. 71st
  • 石山大, 石山大, 中平陽子, 平田梨沙子, 須田義人, 角田茂, 真方文絵, 松田二子. 乳牛のミュラー管融合不全の新たな表現型. 日本胚移植学雑誌. 2024. 45. 3. 132-132
  • 浅井健宏, 南篤, 水流功春, 島野翔太朗, 関口茉莉恵, 橘毅, 栃内亮太, 栃内亮太, 富安博隆, チェンバーズ ジェームズ, et al. 非古典的翻訳開始因子の遺伝子変異マウスは周産期において循環器系機能に異常を示す. 日本実験動物学会総会講演要旨集(Web). 2023. 70th
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Patents (2):
Lectures and oral presentations  (69):
  • Approaches to control allergenicity through animal biotechnology
    (Understanding allergy of livestock products / Seminar series on Food Safety in Asia-Pacific “Emerging topics in our food environment” 2023)
  • フィリピン固有種ハリナシバチ Tetragonula biroi Friese 由来プロポリスのマウスを用いた有用性評価
    (第43回ミツバチ科学研究会 2023)
  • Design of male infertility in mice
    (The 5th annual meeting of living system design research 2020)
  • In vivo genome editing in mice and rats using i-GONAD method.
    (The 5th annual meeting of living system design research 2020)
  • Study on the mechanism and its application of biofilm formation regulated by the conserved ribonuclease, RNase T2, in Escherichia coli.
    (The 5th annual meeting of living system design research 2020)
more...
Education (3):
  • 1998 - 2002 The University of Tokyo Graduate School of Agricultural and Life Sciences Department of Veterinary Medical Science
  • - 2002 The University of Tokyo Graduate School of Agricultural and Life Sciences Department of Veterinary Medical Sciences
  • 1992 - 1998 The University of Tokyo Faculty of Agriculture Veterinary Medical Sciences Course
Professional career (1):
  • Ph.D (Veterinary Medicine) (The University of Tokyo)
Work history (12):
  • 2021/04 - 現在 Kitasato University School of Veterinary Medicine
  • 2020/04 - 現在 Teikyo University of Science Faculty Life & Environmental Sciences
  • 2013/02 - 現在 The University of Tokyo Graduate School of Agricultural and Life Sciences Associate Professor
  • 2013/07 - 2023/03 東海大学医学部 客員准教授
  • 2013/04 - 2023/03 東京理科大学生命医科学研究所 客員准教授
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Committee career (21):
  • 2023/10 - 現在 日本実験動物医学会 理事(前島賞選考委員会 委員長)
  • 2023/05 - 現在 日本サイトカイン学会 幹事
  • 2019 - 現在 特定非営利活動法人獣医系大学間獣医学教育支援機構 幹事
  • 2019 - 現在 特定非営利活動法人獣医系大学間獣医学教育支援機構 獣医学共用試験センター委員
  • 2018/05 - 現在 日本実験動物学会 編集委員会 副委員長
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Awards (3):
  • 2015/05 - 日本実験動物学会 2014年Experimental Animals最優秀論文賞
  • 2014/11 - 優駿会(東京大学獣医学畜産学同窓会) 第2回ヤンソン賞
  • 2010/06 - 日本インターフェロン・サイトカイン学会 優秀ポスター賞
Association Membership(s) (8):
THE JAPANESE SOCIETY OF VETERINARY SCIENCE ,  JAPANESE ASSOCIATION FOR LABORATORY ANIMAL MEDICINE ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE SOCIETY FOR IMMUNOLOGY ,  JAPANESE SOCIETY OF INTERFERON & CYTOKINE RESEARCH ,  JAPANESE ASSOCIATION FOR LABORATORY ANIMAL SCIENCE ,  Japanese Society for Interferon & Cytokine Research ,  Japanese Society for Immunology
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