Rchr
J-GLOBAL ID:200901051214378797   Update date: Nov. 16, 2024

Kadowaki Tomoko

カドワキ トモコ | Kadowaki Tomoko
Affiliation and department:
Homepage URL  (1): http://www.mdp.nagasaki-u.ac.jp/frontier/
Research field  (4): Community dentistry ,  Oral medicine (pathology) ,  Allergies and connective tissue disease ,  Oral medicine
Research keywords  (4): 口腔生化学 ,  細胞生物学 ,  Immunology ,  歯科薬理学
Research theme for competitive and other funds  (32):
  • 2024 - 2027 コホートを用いた歯周病と全身炎症を繋ぐ分子基盤の解明と病態制御への応用
  • 2024 - 2027 小胞輸送系分子を基軸とする関節リウマチモデルマウスの病態解明
  • 2024 - 2027 新規Rabタンパク質機能に着目した歯周疾患発症と病態形成の解析
  • 2024 - 2027 Imaging analysis of the dynamics of lysosomal membranes involved in the acidic environment of oral cancer cells
  • 2023 - 2027 コホートを用いた歯周病と全身炎症を繋ぐ分子基盤の解明と病態制御への応用
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Papers (90):
  • Yu Yamaguchi, Tomoko Kadowaki, Eiko Sakai, Mayuko Noguromi, Shun Oyakawa, Takayuki Tsukuba. Impaired Development of Collagen Antibody-Induced Arthritis in Rab44-Deficient Mice. Biomedicines. 2024. 12. 11. 2504-2504
  • Keiko Sato, Tomoko Kadowaki, Mamoru Takenaka, Mayo Konishi, Miyabi Ando, Takae Onodera, Takayuki Tsukuba. RASEF/Rab45 regulates the formation and sorting of zymogen granules and secretion of digestive enzymes by pancreatic acinar cells. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2024. 1870. 7. 167310-167310
  • Ayuko Tanimoto, Yu Yamaguchi, Tomoko Kadowaki, Eiko Sakai, Shun Oyakawa, Yusuke Ono, Noriaki Yoshida, Takayuki Tsukuba. Rab44 negatively regulates myoblast differentiation by controlling fusogenic protein transport and mTORC1 signaling. Journal of cellular biochemistry. 2023
  • Shun Oyakawa, Yu Yamaguchi, Tomoko Kadowaki, Eiko Sakai, Mayuko Noguromi, Ayuko Tanimoto, Yusuke Ono, Hiroshi Murata, Takayuki Tsukuba. Rab44 deficiency accelerates recovery from muscle damage by regulating mTORC1 signaling and transport of fusogenic regulators. Journal of cellular physiology. 2023
  • Mayuko Noguromi, Yu Yamaguchi, Keiko Sato, Shun Oyakawa, Kuniaki Okamoto, Hiroshi Murata, Takayuki Tsukuba, Tomoko Kadowaki. Rab44 Deficiency Induces Impaired Immune Responses to Nickel Allergy. International journal of molecular sciences. 2023. 24. 2. 994
more...
MISC (94):
  • 上野幹憲, 山口優, 吉田朝美, 平坂勝也, 高橋夏美, 門脇知子, 筑波隆幸, 山口健一. マダイ筋肉由来培養細胞株の樹立. 日本水産学会大会講演要旨集(CD-ROM). 2024. 2024
  • 谷本あゆ子, 山口優, 門脇知子, 坂井詠子, 親川駿, 筑波隆幸. Rab44はmTORC1シグナルを制御することで筋芽細胞の分化を負に制御する. Journal of Oral Biosciences Supplement (Web). 2023. 2023
  • 野黒美麻由子, 野黒美麻由子, 山口優, 佐藤啓子, 親川駿, 筑波隆幸, 門脇知子. Rab44欠損はニッケルアレルギーに対して減弱した免疫反応を惹起する. Journal of Oral Biosciences Supplement (Web). 2023. 2023
  • 親川駿, 山口優, 門脇知子, 坂井詠子, 野黒美麻由子, 野黒美麻由子, 谷本あゆ子, 筑波隆幸. Rab44は,筋衛星細胞におけるmTORC1シグナル伝達と融合制御因子の輸送の調節により,筋再生を負に制御する. Journal of Oral Biosciences Supplement (Web). 2023. 2023
  • 山口優, 門脇知子, 坂井詠子, 野黒美麻由子, 野黒美麻由子, 親川駿, 親川駿, 日浅匠, 日浅匠, 馬渡遥香, et al. Rab44 regulates inflammatory responses in collagen antibody-induced arthritis. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
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Books (8):
  • 歯周病とプロテアーゼ-歯周病原性細菌のヘムおよびアミノ酸獲得機序-
    蛋白質分解 2000
  • Arg-gingipain and Lys-gingipain: a novel class of cysteine proteinases.
    Proteases: New Perspectives, Birkh隔sen Verlag 1999
  • Arg-gingipain and Lys-gingipain : a novel class of cysteine proteinases.
    Proteinases : New Perspectives 1999
  • Structural Characterization of Pathogenic Cysteine Proteinases from the Oral Bacterium Porphyromonas gingivalis.
    Proteolysis in Cell Functions, IOS Press, Amsterdam 1997
  • Biological Roles of a Novel Class of Cysteine Proteinases from Porphyromonas gingivalis in Periodontal Disease Progression.
    "Medical Aspects of Proteases and Protease Inhiibitors" 1997
more...
Lectures and oral presentations  (9):
  • Lysosomal trafficking involved in allergic responses
    (2020)
  • 基礎研究,URA,ワーク・ライフバランスから見た研究戦略
    (第60回歯科基礎医学会学術大会 2018)
  • Porphyromonas gingivalis を標的とした創薬
    (第47回歯科基礎医学会学術大会 2005)
  • Porphyromonas gingivalisプロテアーゼによる宿主細胞傷害機構
    (第78回日本細菌学会総会 2005)
  • Development of potent gingipain inhibitors as tools to prevent the virulence of Porphyromonas gingivalis
    (3rd General Meeting of the International Proteolysis Society 2003)
more...
Education (4):
  • 1991 - 1995 Kyushu University
  • - 1995 Kyushu University Graduate School, Division of Dental Research
  • 1984 - 1990 Kyushu University School of Dentistry
  • - 1990 Kyushu University Faculty of Dentistry
Professional career (1):
  • (BLANK) (Kyushu University)
Work history (11):
  • 2024/04 - 現在 Nagasaki University Director(Diversity and Inclusion)
  • 2021/03 - 現在 Nagasaki University Graduate School of Biomedical Sciences
  • 2014/11 - 2021/02 Nagasaki University Graduate School of Biomedical Sciences associate professor
  • 2012/02 - 2014/10 Nagasaki University
  • 2009/04 - 2012/01 Nagasaki University
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Committee career (3):
  • 2024/04 - 現在 長崎市人権男女共同参画室 審議委員
  • 2024/04 - 現在 長崎県男女共同参画・女性活躍推進室 長崎県男女共同参画審議会委員
  • 2022/09 - 現在 Japanese Association for Oral Biology delegate
Awards (3):
  • 2004 - JB論文賞
  • 2002 - 優秀演題賞
  • 1999 - 歯科基礎医学会賞
Association Membership(s) (3):
日本分子生物学会 ,  歯科基礎医学会 ,  日本生化学会
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