Rchr
J-GLOBAL ID：200901051407015187   Update date: Nov. 26, 2024

Yosuke Nakazawa

ナカザワ ヨウスケ | Yosuke Nakazawa
Affiliation and department：
Keio University Faculty of Pharmacy Department of Pharmacy

About Keio University Faculty of Pharmacy Department of Pharmacy


Job title： Assistant Professor/Senior Assistant Professor
Research field  (1)： Ophthalmology
Research theme for competitive and other funds  (9)：
  • 2023 - 2026 Analysis of the mechanism of presbyopia and development of animal models
  • 2020 - 2023 Roles for the TRPVs channels in the lens in the initiation of presbyopia
  • 2021 - 2022 Mechanobiological analysis of cell-basement membrane interaction during eye lens morphogenesis
  • 2020 - 2022 Roles for the mechanosensitive channels (TRPV1 and TRPV4) in the initiation of presb yopia and development of cataract
  • 2018 - 2019 老眼発症遅延薬の開発を見据えて:老眼発症メカニズムの解明と老眼モデル動物の開発
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Papers (89)：
  • Otake H., Masuda S., Yamamoto T., Miyata Y., Nakazawa Y., Yamamoto N., Taga A., Sasaki H., Nagai N. Semiquantitative analysis of protein expression in heated rat lens using shotgun proteomics. Molecular medicine reports. 2025. 31. 1
  • Yosuke Nakazawa, Yumika Kuno, Hibiki Shimada, Noriaki Nagai, Noriko Hiramatsu, Shun Takeda, Naoki Yamamoto, Megumi Funakoshi-Tago, Hiroshi Sasaki. High ambient temperature may induce presbyopia via TRPV1 activation. Medical molecular morphology. 2024
  • 門脇玲太, 明和亮伍, 岩井誓治, 永田万由美, 松島博之, 中澤洋介, 山本直樹, 佐々木 洋, 長井紀章. ニルバジピンナノサスペンション点眼による眼組織への 薬物送達:経口投与時における薬物挙動との比較. 日本白内障学会誌. 2024. 36. 95-99
  • 門脇玲太, 浅井拓己, 出口粧央里, 大竹裕子, 岡本紀夫, 中澤洋介, 佐々木 洋, 長井紀章. 亜セレン酸誘発白内障モデルの混濁過程における 水晶体弾性力の変化. 日本白内障学会誌. 2024. 36. 104-109
  • Mikako Oka, Masayasu Bando, Yosuke Nakazawa, Hiroko Ushikubo, Takashi Yoshikado, Kenji Okada, Koji Chiba, Makoto Takehana. Identification of Ascorbate Free Radical Reductase in the Lens. The Journal of the Japanese Society for Cataract Research. 2024. 36. 113-122
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MISC (13)：
  • 土岐友理, 中澤洋介, 助川心優. Piezo1 チャネルの活性化はTGM2 の活性化を介して 水晶体硬化を発症する. 日本白内障学会誌. 2024. 36. 124-125
  • Yumika Kuno, Yosuke Nakazawa. Ambient Temperature affects TRPV1 activity in lens Epithelial Cells. The Journal of the Japanese Society for Cataract Research. 2024. 36. 69-71
  • Kana Aihara, Yosuke Nakazawa. Role of Aquaporins and Connexins in the Lens and Contribution to Cataract Development. The Journal of the Japanese Society for Cataract Research. 2024. 36. 82-84
  • 長井紀章, 門脇玲太, 浅井拓己, 出口粧央里, 大竹裕子, 岡本紀夫, 中澤洋介, MANJU Misra, 佐々木洋. 水晶体硬化条件の設定と指数式を用いた硬度評価の提案. 日本老視学会学術総会プログラム・抄録集. 2024. 2nd
  • 中澤洋介, 多胡めぐみ, 田村悦臣. コーヒー摂取と白内障予防. 食と医療. 2023. 27. 40-46
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Lectures and oral presentations  (119)：
  • 水晶体温度上昇による白内障進行要因の解明を目指して:ヒト由来細胞 iHLEC-NY2 の プロテオミクス解析
    (The 63st Annual Meetings of the Japanese Society for Cataract Research/ The 50th Annual Meetings of the Japanese Society for Crystallin lens Research 2024)
  • チャネルタンパク質と疾患
    (The 63st Annual Meetings of the Japanese Society for Cataract Research/ The 50th Annual Meetings of the Japanese Society for Crystallin lens Research 2024)
  • 水晶体上皮細胞において、TRPV1 は Calpain-PTP を介して EMT を抑制する
    (The 63st Annual Meetings of the Japanese Society for Cataract Research/ The 50th Annual Meetings of the Japanese Society for Crystallin lens Research 2024)
  • The physical changes by aging in the lens and treatment its related diseases.
    (日本薬学会第144年会 2024)
  • 基礎研究で老視に挑む!
    (第17回 眼抗加齢医学研究会 アップデートセミナー 2024)
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Professional career (1)：
  • 博士 (薬学)
Work history (5)：
  • 2019/04 - 現在 Fuculty of Pharmacy, Keio University Senior Lecturer
  • 2012/04 - 2019/03 慶應義塾大学薬学部 助教
  • 2016/09 - 2017/08 The University of Auckland Faculty of Medical and Health Sciences Visiting Researcher
  • 2009/04 - 2012/03 慶應義塾大学薬学部 助手
  • 2005/04 - 2009/03 Faculity of pahrmacy, setsunan university 助手
Committee career (12)：
  • 2024/08 - 現在 白内障学会 理事
  • 2022/04 - 現在 日本老視学会 理事
  • 2022/01 - 現在 Ocular Scientific Meeting 監事
  • 2021/11 - 現在 日本白内障学会 The Journal of The Japanese Society for Cataract Research, Editor-in-Chief
  • 2021/04 - 現在 日本眼薬理学会 評議員
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Awards (17)：
  • 2024/07 - The japanese Society for clinical Molecular Morphology Best Author Award - Molecular Medicine Morphology Aquaporins contribute to vacuoles formation in Nile grass type II diabetic rats
  • 2024/07 - The japanese Society for clinical Molecular Morphology Best Author Award - Molecular Medicine Morphology Aquaporins contribute to vacuoles formation in Nile grass type II diabetic rats
  • 2023/07 - 62nd Annula Meeting of the Japanese Society for Catarct Research 優秀演題賞 Verification of Piezo channels expression in the mouse lens
  • 2021/11 - Japanese Society for Cataract Research Best Presentation Award in Japanese Society for Cataract Research TRPV1 activation can prevents Posterior capsule opacification
  • 2019/11 - Japan Health Fundation 2019年度 助成研究発表会 優秀賞
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