Rchr
J-GLOBAL ID:200901051588443711
Update date: Apr. 15, 2020
Kawashima Toshiyuki
カワシマ トシユキ | Kawashima Toshiyuki
Affiliation and department:
The University of Tokyo The Institute of Medical Science
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Job title:
Assistant Professor
Research field (3):
Hematology and oncology
, Pathobiochemistry
, Cell biology
Research keywords (7):
分子腫瘍学
, 血液学
, 細胞周期・細胞分化
, Molecular Oncology
, Homatology
, Cellular differentiation
, Cell Cycle
Research theme for competitive and other funds (5):
2004 - IL-6阻害剤の同定と解析
1998 - 白血病発症機構に関する研究
1998 - 細胞周期・細胞分化の調節機構に対する研究
1998 - Study on the mechanism of leukemogenesis
Study on the regulation of cell growth and differentiation
MISC (11):
Kawashima, T, Bao, Y.C, Moon, Y, Tonozuka, Y, Minoshima, Y, Hatori, T, Kiyono, M, Nosaka, T, Nakajima, H, Williams, D.A, et al. Rac1とMgcRacGAPは活性型STAT転写因子の核内移行に必要である. J. Cell Biol. 2006. 175. 6. 937
Kawashima, T, Bao, Y.C, Moon, Y, Tonozuka, Y, Minoshima, Y, Hatori, T, Kiyono, M, Nosaka, T, Nakajima, H, Williams, D.A, et al. Rac1 and a GTPase activating protein MgcRacGAP are required for nuclear translocation of STAT transcription factors. J. Cell Biol. 2006. 175. 6. 937-946
STAT5はNF
K
B p65を介しIL-6の自己生産によりM1白血病細胞をマクロファージへ分化誘導する. 2001. 167, 3652-3660
HIROSE K, KAWASHIMA T, IWAMOTO I, NOSAKA T, KITAMURA T. MgcRacGAPは紡錘系および中央体を制御し細胞質分裂に関与する. Journal of Biological Chemistry. 2001. 276. 8. 5821-5828
STAT5 Induces Macrophage Differentiation of M1 Leukemia Cells Through Activation of IL-6 Production Mediated by NF-
K
B p65. The Journal of Immunology. 2001. 167, 3652-3660
more...
Patents (1):
インターロイキン-6(IL-6)シグナル伝達阻害剤スクリーニング法
Education (4):
- 1998 Keio University Graduate School of Medicine
- 1998 Keio University Graduate School, Division of Medicine
- 1994 Keio University School of Medicine
- 1994 Keio University Faculty of Medicine
Professional career (1):
(BLANK) (Keio University)
Work history (7):
2007 - - 助教
2002 - - 寄附研究部門教員
2002 - - Assistant Professor
2001 - - COE研究員(リサーチアソシエイト)
2001 - - Research Associate
1998 - 2000 客員研究員
1998 - 2000 (Research Associate)
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Association Membership(s) (2):
日本免疫学会
, 日本血液学会
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