Nomura Hajime

ノムラハジメ | Nomura Hajime

Affiliation and department：
Job title： associate professor

Research field (3)： Medical biochemistry , Molecular biology , Cell biology

Research keywords (1)： Life science

Research theme for competitive and other funds (6)：

2004 - 現在 HTLV-1ウイルスのATL発症メカニズムの解析
1998 - 現在糖由来生成物の細胞生物学的影響についての解析
2010 - 2011 発症危険度判別によるATL発症リスク診断システムの開発
2008 - 2011 The molecules related with HTLV-1 infection and the identification of the risk factors for ATL.
2003 - 2004 The analysis of onset of familial amyotrophic lateral sclerosis(FALS) with His46Arg point mutation

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Papers (23)：

Kazumi Umeki, Asato Yasuda, Kunihiko Umekita, Ryoya Megumi, Hajime Nomura, Takeshi Kawaguchi, Motohiro Matsuda, Ichiro Takajo, Masayuki Shimojima, Akihiko Okayama. Detection of anti-SFTSV nuclear protein antibody in the acute phase sera of patients using double-antigen ELISA and immunochromatography. Journal of virological methods. 2020. 285. 113942-113942
Nomura H, Umekita K, Hashikura Y, Umeki K, Yamamoto I, Aratake Y, Saito M, Hasegawa H, Yanagihara K, Okayama A. Diversity of cell phenotypes among MT-2 cell lines affects the growth of U937 cells and cytokine production. Human cell. 2019. 32. 2. 185-192
Nomura Hajime, Umekita Kunihiko, Hashikura Yuuki, Umeki Kazumi, Yamamoto Ikuo, Aratake Yatsuki, Saito Mineki, Hasegawa Hiroo, Yanagihara Katsunori, Okayama Akihiko. Diversity of cell phenotypes among MT-2 cell lines affects the growth of U937 cells and cytokine production. HUMAN CELL. 2019. 32. 2. 185-192
Umekita K, Miyauchi S, Nomura H, Umeki K, Okayama A. Neutrophil-derived lactoferrin induces the inflammatory responses of rheumatoid arthritis synovial fibroblasts via Toll-like receptor 4. Clin Exp Rheumatol. 2019
Yamada A, Umeki K, Saeki Y, Hashikura Y, Nomura H, Yamamoto I, Umekita K, Takajo I, Koshimoto C, Okayama A. Detection of microbial genes in a single leukocyte by polymerase chain reaction following laser capture microdissection. Journal of Microbiological Methods. 2018. 155. 42-48

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MISC (8)：

Kunihiko Umekita, Shunichi Miyauchi, Koshou Iwao, Mao Rikitake, Yuuki Rikitake, Chihiro Kawada, Ayako Aizawa, Yumi Kariya, Motohiro Matsuda, Takeshi Kawaguchi, et al. Exosomes Derived from T Lymphocytes Enhance Expression of CXCL10 Induced By IFN-gamma in Rheumatoid Arthritis Synovial Fibroblasts Via Pattern Recognition Receptor, RIG-I. ARTHRITIS & RHEUMATOLOGY. 2017. 69
K. Umekita, S. Miyauchi, K. Kubo, A. Kawano, K. Iwao, M. Komura, M. Matsuda, I. Takajo, H. Nomura, Y. Nagatomo, et al. HUMAN T CELL LEUKEMIA VIRUS TYPE 1 (HTLV-1) EXACERBATES RHEUMATOID ARTHRITIS; EXOSOMES AND IFN-GAMMA DERIVED FROM HTLV-1 INFECTED CELLS ENHANCE THE INFLAMMATORY RESPONSE OF RHEUMATOID ARTHRITIS SYNOVIAL FIBROBLASTS VIA PATTERN RECOGNITION RECEPTOR, RIG-I. ANNALS OF THE RHEUMATIC DISEASES. 2017. 76. 1054-1054
Kunihiko Umekita, Shunichi Miyauchi, Kazuyoshi Kubo, Kazumi Umeki, Hajime Nomura, Mao Komura, Koushou Iwao, Ichiro Takajo, Yasuhiro Nagatomo, Toshihiko Hidaka, et al. IL-6 May Have an Important Role in the Resistance to Anti-TNF Therapies of Human T-Lymphotropic Virus Type 1 (HTLV-1) Positive Rheumatoid Arthritis (RA) Patients; HTLV-1 Infected Cells Activate the Inflammatory Responses of RA Synovial Fibroblasts. ARTHRITIS & RHEUMATOLOGY. 2015. 67
Kunihiko Umekita, Shunichi Miyauchi, Kazuyoshi Kubo, Hajime Nomura, Kazumi Umeki, Koushou Iwao, Mao Komura, Akihiko Okayama. Neutrophil-Derived Lactoferrin Regulates the Activity of NFAT5 in Rheumatoid Arthritis Synovial Fibroblasts Via Toll-like Receptor 4. ARTHRITIS & RHEUMATOLOGY. 2015. 67
緒方良一, 青木義政, 藤川恵子, 菅文恵, 猪﨑みさき, 守田政宣, 北中明, 野村創, 岡山昭彦. カルシウムおよびγGT測定に影響を及ぼしたlgM-λ型M-蛋白血症. 日本臨床化学会九州支部会誌. 2015. 25. 1-5

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Lectures and oral presentations (26)：

Neutrophil-Derived Lactoferrin Regulates the Activity of NFAT5 in Rheumatoid Arthritis Synovial Fibroblasts Via Toll-like Receptor 4.
(2015 ACR/ARHP Annual Meeting. 2015)
IL-6 May Have an Important Role in the Resistance to Anti-TNF Therapies of Human T-Lymphotropic Virus Type 1 (HTLV-1) Positive Rheumatoid Arthritis (RA) Patients; HTLV-1 Infected Cells Activate the Inflammatory Responses of RA Synovial Fibroblasts.
(2015 ACR/ARHP Annual Meeting. 2015)
HTLV-1感染による関節リウマチ病態の修飾機構の検討.
(第2回日本HTLV-1学会学術集会 2015)
Expression of CD26/DPP IV(Dipeptidyl peptidase IV) in rat thyroid lesions induced by diisopropanolnitrosamine (DIPN).
(The 7th Japan, Taiwan, Korea Cytotechnology Joint Meeting. 2015)
胸水中細胞より株価したMerkel細胞癌の細胞学的特徴.
(日本ヒト細胞学会学術集会第32回. 2014)

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Education (3)：

- 1992 Kyushu University Graduate School, Division of Natural Science
- 1988 Kyushu University Graduate School, Division of Natural Science
- 1984 Kyushu University Faculty of Science

Professional career (3)：

博士(医学) (宮崎医科大学)
理学修士 (九州大学)
理学士 (九州大学)

Work history (4)：

2024/04 - 現在 Kyushu University of Medical Science School of Medical Life Sciences Department of Medical Life Sciences
2019/04 - 2024/03 Kyushu University of Health and Welfare Department of Medical Life Science Faculty of Medical Bioscience Associate Professor
2007/04 - 2019/03 University of Miyazaki Faculty of Madicine School of Madicine Internal medicine course immunity infection condition study field Assistant Professor
1992/12/01 - 2007/03/31 University of Miyazaki Faculty of Madicine School of Madicine Internal medicine course immunity infection condition study field Research Assistant

Association Membership(s) (5)：

日本分子生物学会 , 日本癌学会 , 日本臨床検査医学会 , 日本臨床化学会 , 生物試料分析学会

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