NAOHIRO WAKISAKA

Research theme for competitive and other funds (13)：

2017 - 2021 Analysis of oncogenesis and heterogenesity in nasopharyngeal carcinoma and development of novel therapy
2016 - 2020 内因性免疫による頭頸部ウイルス発癌における内分泌撹乱物質の関与と新規治療法の開発
2015 - 2018 Association between activation induced cytidine deaminase and HPV positive oropharyngeal carcinogenesis
2014 - 2017 Therapeutic approach to recurrent respiratory papillomatosis from the perspective of signal transduction of human papillomavirus
2014 - 2017 Analysis for the role of cell competition in the tumorigenesis and treatment strategy of nasopharyngeal carcinoma

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Papers (112)：

Naohiro Wakisaka, Makiko Moriyama-Kita, Satoru Kondo, Eiji Kobayashi, Takayoshi Ueno, Yosuke Nakanishi, Kazuhira Endo, Hisashi Sugimoto, Tomokazu Yoshizaki. Immune-Related Gene Expression Profile at Peritumoral Tonsillar Tissue Is Modified by Oropharyngeal Cancer Nodal Status. The American journal of pathology. 2023
Takahito Kondo, Kiyoaki Tsukahara, Daisuke Kawakita, Seiichi Yoshimoto, Kouki Miura, Masashi Sugasawa, Kazuaki Chikamatsu, Takashi Matsuzuka, Isao Oze, Morimasa Kitamura, et al. Macroscopic and multiple metastases in sentinel lymph node biopsy are respectively associated with poor prognosis in early oral cancer. International journal of clinical oncology. 2023. 28. 4. 512-520
Satoru Kondo, Atsushi Okabe, Takuya Nakagawa, Keisuke Matsusaka, Masaki Fukuyo, Bahityar Rahmutulla, Hirotomo Dochi, Harue Mizokami, Yuki Kitagawa, Tomoya Kurokawa, et al. Repression of DERL3 via DNA methylation by Epstein-Barr virus latent membrane protein 1 in nasopharyngeal carcinoma. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2022. 166598-166598
Hirotomo Dochi, Satoru Kondo, Takayuki Murata, Masaki Fukuyo, Asuka Nanbo, Kousho Wakae, Wen-Ping Jiang, Toshihide Hamabe-Horiike, Mariko Tanaka, Takumi Nishiuchi, et al. Estrogen induces the expression of EBV lytic protein ZEBRA, a marker of poor prognosis in nasopharyngeal carcinoma. Cancer science. 2022. 113. 8. 2862-2877
Satoru Kondo, Yusuke Okuno, Takayuki Murata, Hirotomo Dochi, Naohiro Wakisaka, Harue Mizokami, Makiko Moriyama-Kita, Eiji Kobayashi, Makoto Kano, Takeshi Komori, et al. EBV genome variations enhance clinicopathological features of nasopharyngeal carcinoma in a non-endemic region. Cancer science. 2022. 113. 7. 2446-2456

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MISC (150)：

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Lectures and oral presentations (9)：

Adjuvant chemotherapy with an oral fluoropyrimidine, S-1, following reduced- RADPLAT in advanced laryngeal cancer
(14th Korea Japan Joint Meeting of Otorhinolaryngology-Head and Neck Surgery 2012)
どのように治療法を使い分けてゆくか. 化学放射線療法(動注化学療法)
(第24回日本喉頭科学会 2012)
Regulation of cis-presentation of CD8+ T-cell epitopes by EBV-encoded LMP1 through self-aggregation
(14th International Symposiumu on EBV 2010)
Induction of receptor for advanced glycation end products by EpsteinBarr virus latent membrane protein 1 in nasopharyngeal carcinoma.
(The12th Japan-Korea Joint Meeting of Otorhinolaryngology-Head and Neck Surgery 2008)
EBV LMP1induces and causes release of fibroblast Growth factor-2.
(The10th Japan-Korea Joint Meeting of Otorhinolaryngology-Head and Neck Surgery 2004)

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