Yamaguchi Yoko

ヤマグチヨウコ | Yamaguchi Yoko

Affiliation and department：
Job title： Adjunct Professor
Homepage URL (1)： http://www.cityofhope.org/people/fujita-yamaguchi-yoko

Research field (2)： Functional biochemistry , Structural biochemistry

Research keywords (5)： New developments of 40-old research on SHA lectin from Streptomyces , 糖鎖特異的単鎖抗体の発現・解析 , IGF-I recptor signaling , がん分子標的治療法 , Molecular targeted-strategy utilizing antibodies against carbohydrates and IGF-I receptor

Research theme for competitive and other funds (6)：

2010 - 2012 新規糖鎖特異的単鎖抗体の大腸菌発現系による大量発現と糖鎖結合性解析
2003 - 2009 Production of single chain antibodies (scFvs) against a variety of carbohydrate epitopes
2003 - 2008 研究領域「糖鎖の生物機能の解明と利用技術」研究課題「糖鎖構造特異的単鎖抗体ライブラリーの構築」
2005 - 2007 インスリン様増殖因子(IGF)-I 受容体とがん分子標的治療法
2005 - 2007 Single chain antibodies against IGF-(]G0001[) receptor as potential therapeutics for cancer

Show all

Papers (25)：

Yoko Fujita-Yamaguchi, Hideyuki Muramatsu, Alonso Tapia, Karine Bagramyan, Moksha Desai, Yasuhiro Takehana, Masayuki Igarashi, Yoshiki Yamaguchi, Markus Kalkum. Proteolytic Processing, Maturation, and Unique Synteny of the Streptomyces Hemagglutinin SHA. Microbiology spectrum. 2021. 9. 2. e0076621
Sarah C Shuck, Teresa Hong, Markus Kalkum, Ryo Igarashi, Kota Kajiya, John Termini, Kazuo Yamamoto, Yoko Fujita-Yamaguchi. MLS128 antibody-induced suppression of colon cancer cell growth is mediated by a desmocollin and a 110 kDa glycoprotein. Bioscience trends. 2019. 13. 3. 216-224
Naoki Takizawa, Yoshitoshi Ogura, Yoko Fujita, Takeshi Noda, Hideki Shigematsu, Tetsuya Hayashi, Ken Kurokawa. Local structural changes of the influenza A virus ribonucleoprotein complex by single mutations in the specific residues involved in efficient genome packaging. Virology. 2019. 531. 126-140
Fujita-Yamaguchi Y, Bagramyan K, Yamaguchi Y, Ikeda A, Dohmae N, Hong TB, Kalkum M. Mass spectrometric revival of an l-rhamnose- and d-galactose-specific lectin from a lost strain of Streptomyces. The Journal of biological chemistry. 2018. 293. 1. 368-378
Nakata M, Kawaguchi S, Oikawa A, Inamura A, Nomoto S, Miyai H, Nonaka T, Ichimi S, Fujita-Yamaguchi Y, Luo C, et al. An aqueous extract from toad skin prevents gelatinase activities derived from fetal serum albumin and serum-free culture medium of human breast carcinoma MDA-MB-231 cells. Drug discoveries & therapeutics. 2016. 9. 6. 417-421

ｍore...

MISC (166)：

Yoko Fujita-Yamaguchi, Yoshiki Yamaguchi, Akemi Ikeda, Naoshi Domae, Karine Bagramyan, Teresa B. Hong, John P. Murad, Markus Kalkum. Primary structure determination of a blood group B-specific lectin purified from Streptomyces sp 27S5 reveals insight into its mechanism of expression and unique structural features. GLYCOBIOLOGY. 2016. 26. 12. 1415-1415
Markus Kalkum, Teresa Hong, Karine Bagramyan, Yoko Fujita-Yamaguchi. Proteomics and Genomics Provide Novel Insights Into Streptomyces Lectin Biochemistry. GLYCOBIOLOGY. 2014. 24. 11. 1115-1116
Yoko Fujita-Yamaguchi, Astufumi Nakazawa, Noriyuki Yuasa. Expression and Purification of Anti-IGF-I Receptor 1H7 Constructs in Drosophila S2 Cells. ENDOCRINE REVIEWS. 2014. 35. 3
Hiroyuki Kato, Takahito Fukuda, Noriyuki Yuasa, Yoko Fujita-Yamaguchi. Expression, purification, and refolding of single chain antibodies (scFvs) from inclusion bodies. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2012. 244
Tsubasa Koyama, Daisuke Takada, Yoshiki Yamaguchi, Noriyuki Yuasa, Ayano Matsumoto-Takasaki, Yoko Fujita-Yamaguchi. In vitro production of anticarbohydrate antibodies: Purification of anti-T antigen antibodies (scFvs) from E. coli inclusion bodies and Drosophila S2 cell culture media. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2012. 244

ｍore...

Books (6)：

Isolation and characterization of antibodies against three consecutive Tn-antigen clusters from a phage library displaying human single-chain variable fragments.
J. Biochem. (Sakai, K., Yuasa, N., Tsukamoto, K., Takasaki-Matsumoto, A., Yajima, Y., Sato, R., Kawakami, H., Mizuno, M., Takayanagi, A., Shimizu, N., Nakata, M., and Fujita-Yamaguchi, Y. ) 2010
Preparation of asialo-agalacto-glycophorin A for screening of anti-Tn antibodies.
Biosci. Trends. Koizumi, T., Matsumoto-Takasaki, A., Nakada, H., Nakata, M., Fujita-Yamaguchi, Y. 2010
Production of anti-carbohydrate antibodies by phage-display technologies: Potential impairment of cell growth as a result of endogenous expression.
J. Biol. Chem. (Yuasa, N., Zhang, W., Goto, T., Sakaue, H., Matsumoto- Takasaki, A., Kimura, M., Ohshima, H., Tsuchida, Y., Koizumi, T., Sakai, K., Kojima, T., Yamamoto, K., Nakata, M., and Fujita-Yamaguchi, Y.) 2010
Preparation of asialo-agalacto-glycophorin A for screening of anti-Tn antibodies.
Biosci. Trends. (Koizumi, T., Matsumoto-Takasaki, A., Nakada, H., Nakata, M., Fujita-Yamaguchi, Y.) 2010
Production of anti-carbohydrate antibodies by phage-display technologies: Potential impairment of cell growth as a result of endogenous expression.
J. Biol. Chem. (110) Yuasa, N., Zhang, W., Goto, T., Sakaue, H., Matsumoto- Takasaki, A., Kimura, M., Ohshima, H., Tsuchida, Y., Koizumi, T., Sakai, K., Kojima, T., Yamamoto, K., Nakata, M., and Fujita-Yamaguchi, Y.) 2010

ｍore...

Education (6)：

- 1977 The University of Tokyo
- 1977 The University of Tokyo Graduate School, Division of Agriculture Agricultural Chemistry
- 1973 The University of Tokyo
- 1973 The University of Tokyo Graduate School, Division of Agriculture Agricultural Chemistry
- 1971 Saitama University

Show all

Professional career (1)：

Ph.D. in Biochemistry (The University of Tokyo)

Work history (8)：

2022/05 - 現在 Juntendo University Graduate School of Medicine Adjunct Professor
2014/04 - 現在 BRI of City of Hope Diabetes & Metabolism Res. Inst. Professor Emeritus
2000 - 2014/03 Tokai University School of Engineering, Department of Applied Biochemistry
1981 - 2000 米国City of Hopeベックマン研究所Assistant ProfessorからProfessor of Molecular Biology
1981 - 2000 Assistant Professor to Professor of Molecular Biology at Beckman Research Institute of the City of Hope

Show all

Association Membership(s) (3)：

アメリカ内分泌学会(The Endocrine Society) , 日本生化学学会 , アメリカ生化学・分子生物学会(American Society for Biochemistry and Molecular Biology)

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page