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J-GLOBAL ID：200901052001648398   Update date: Oct. 03, 2024

Iyoda Takuya

イヨダ タクヤ | Iyoda Takuya
Research field  (1)： Pathobiochemistry
Research keywords  (8)： macrophages ,  ECM ,  cell adhesion ,  chronic inflammation ,  cellular senescence ,  atherosclerosis ,  tumor/cancer ,  innate immunity
Research theme for competitive and other funds  (4)：
  • 2011 - 2013 Molecular mechanism for malignant cell transformationinduced by a peptide derived from tenascin C through integrin activation
  • 2010 - 2012 Physiological role of calcium transport system regulated by phosphatidylinositol
  • 2008 - 2010 Analysis of physiological function of calcium transporters in epithelial cells and its pathological mechanisms
  • 2008 - 2009 Role of cation transporter in the regulation of macrophage function.
Papers (64)：
  • Yuya Tsurudome, Yumi Takahata, Nao Morita, Soma Yamauchi, Takuya Iyoda, Michiko Horiguchi, Kentaro Ushijima. Increased SPARC in brain microvessels of ob/ob mice accelerates molecular transport into the brain accompany with albumin. Life Sciences. 2024. 355. 122990-122990
  • Motomichi Fujita, Manabu Sasada, Takuya Iyoda, Fumio Fukai. Involvement of Matricellular Proteins in Cellular Senescence: Potential Therapeutic Targets for Age-Related Diseases. International Journal of Molecular Sciences. 2024. 25. 12. 6591-6591
  • Takuya Iyoda, Asayo Ohishi, Yunong Wang, Miyabi-Shara Yokoyama, Mika Kazama, Naoyuki Okita, Sachiye Inouye, Yoshimi Nakagawa, Hitoshi Shimano, Fumio Fukai. Bioactive TNIIIA2 Sequence in Tenascin-C Is Responsible for Macrophage Foam Cell Transformation; Potential of FNIII14 Peptide Derived from Fibronectin in Suppression of Atherosclerotic Plaque Formation. International Journal of Molecular Sciences. 2024. 25. 3. 1825-1825
  • Inouye S, Kubo T, Miyamoto T, Iyoda T, Okita N, Akagi R. Heat shock-induced heme oxygenase-1 expression in a mouse hepatoma cell line is dependent on HSF1 and modified by NRF2 and BACH1. Genes to Cells. 2023. 12. 12. 719-730
  • Fujita M, Sasada M, Eguchi M, Iyoda T, Okuyama S, Osawa T, Tsuzuranuki K, Sakamoto M, Hagiwara Y, Matsumura M, et al. Induction of cellular senescence in fibroblasts through beta1-integrin activation by tenascin-C-derived peptide and its protumor effect. Am J Cancer Res. 2021. 11. 9. 4364-4379
ｍore...
MISC (18)：
  • 廣川茉衣, 堀口道子, 伊豫田拓也, 深井文雄, 山下親正. TNIIIA2ペプチドの新規COPD治療薬としての有用性の検討. 日本薬学会関東支部大会講演要旨集. 2014. 58th
  • 伊豫田 拓也, 羽賀 誠, 板垣 圭祐, 内藤 壽彦, 長内 研大, 深井 文雄. フィブロネクチン分子内の反接着機能部位FNIII14に対する受容体としての、タンパク質翻訳伸長因子eEF1Aの新規機能. 日本薬学会年会要旨集. 2012. 132年会. 3. 91-91
  • 岡田 佑子, 小野田 章人, 伊豫田 拓也, 大脇 敏之, 深井 文雄. テネシン-Cの反接着作用とそれに基づく細胞機能制御の分子機構. 日本結合組織学会学術大会・マトリックス研究会大会合同学術集会プログラム・抄録集. 2011. 43回・58回. 73-73
  • Shintaro Yamamoto, Takuya Iyoda, Satomi Kita, Toshiki Yamada, Takahiro Iwamoto. OSU-03012, a novel celecoxib derivative, suppresses volume-regulated anion channels in mouse ventricular cells. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2011. 115. 264P-264P
  • 松井 雪子, 喜多 紗斗美, 伊豫田 拓也, 桂木 猛, 小室 一成, 岩本 隆宏, 大慈弥 裕之. O2-2 マウス下肢虚血モデルにおけるプロスタグランジンE1製剤の血管新生促進作用とNCX1輸送体(一般演題2(口演),第52回日本平滑筋学会総会). 日本平滑筋学会雑誌. 2010. 14. 1. "J-24"
ｍore...
Patents (1)：
  • 細胞の転移又は浸潤抑制剤
Books (5)：
  • Deregulation of platelet-derived growth factor (PDGF)-dependent cell proliferation through potentiated and sustained activation of β1-integrin, induced by tenascin-C-derived peptide TNIIIA2
    Nova publishers 2017 ISBN:9781536121780
  • Integrin-dependent cell regulation and its clinical application.
    Encyclopedia of Biocolloid and Biointerface Science 2016
  • Cell regulation through adhesion to the extracellular matrix via adhesion molecule, integrins -Therapeutic application of integrin activation-modulating peptides-
    ELSEVIER 2014
  • 人体機能学IV 薬理学テキスト
    福岡大学医学部薬理学教室 2010
  • Na+/Ca2+ 交換体を標的とした新規 Ca2+ 調節薬の開発
    メディカルドゥ・遺伝子医学MOOK 2009
Lectures and oral presentations  (169)：
  • テネイシン-C 分子内領域による細胞機能調節と動脈硬化
    (Matricell Forum 2021)
  • Abnormal signaling form ECM and macrophage foam cell formation.
    (2019)
  • Abnormal signaling from ECM and macrophage foam cell formation.
    (2019)
  • 多糖複合フィルムが異なる細胞種へ与える影響の評価
    (第39回日本バイオマテリアル学会大会 2017)
  • 熱プレス法により作製した多糖複合フィルムと細胞との相互作用の解析
    (第66回高分子討論会 2017)
ｍore...
Education (2)：
  • 2000 - 2005 Toho University Graduate School, Division of Science molecular biology
  • - 2000 Toho University Faculty of Science Biomolecular Science
Work history (6)：
  • 2024/04 - 現在 Tokyo University of Science,Yamaguchi Faculty of Pharmaceutical Sciences
  • 2018/04 - 2024/03 Tokyo University of Science,Yamaguchi
  • 2016/04 - 2018/03 Tokyo University of Science Faculty of Pharmaceutical Sciences
  • 2011/04 - 2016/03 Tokyo University of Science. Faculty of Pharmaceutical Science; Assistant-Prof
  • 2007/10 - 2011/03 Fukuoka University, Faculty of Medicine; Assistant-Prof
Show all
Committee career (1)：
  • 2007 - 日本トランスポーター研究会 幹事
Awards (1)：
  • 2009/02 - 第38回 心脈管作動物質学会 若手研究奨励賞
Association Membership(s) (11)：
THE JAPANESE PEPTIDE SOCIETY ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE ,  THE JAPANESE ASSOCIATION FOR MOLECULAR TARGET THERAPY OF CANCER ,  結合組織学会 ,  JAPANESE SOCIETY FOR IMMUNOLOGY ,  日本トランスポーター研究会 ,  日本循環薬理学会 ,  日本平滑筋学会 ,  日本心脈管作動物質学会 ,  日本分子生物学会
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