Rchr
J-GLOBAL ID:200901052001648398   Update date: Dec. 16, 2020

Iyoda Takuya

イヨダ タクヤ | Iyoda Takuya
Research field  (1): Pharmaceuticals - health and biochemistry
Research keywords  (1): innate immunity, cell adhesion, chronic inflammation, tumor, atherosclerosis
Research theme for competitive and other funds  (4):
  • 2011 - 2013 Molecular mechanism for malignant cell transformationinduced by a peptide derived from tenascin C through integrin activation
  • 2010 - 2012 Physiological role of calcium transport system regulated by phosphatidylinositol
  • 2008 - 2010 Analysis of physiological function of calcium transporters in epithelial cells and its pathological mechanisms
  • 2008 - 2009 Role of cation transporter in the regulation of macrophage function.
Papers (53):
  • Takuya Iyoda, Motomichi Fujita, Fumio Fukai. Biologically Active TNIIIA2 Region in Tenascin-C Molecule: A Major Contributor to Elicit Aggressive Malignant Phenotypes From Tumors/Tumor Stroma. Frontiers in Immunology. 2020. 11
  • Keisuke Itagaki, Manabu Sasada, Satoru Miyazaki, Takuya Iyoda, Takahiro Imaizumi, Makoto Haga, Akira Kuga, Hiroki Inomata, Yosuke Kondo, Satoshi Osada, et al. Exposure of the cryptic de-adhesive site FNIII14 in fibronectin molecule and its binding to membrane-type eEF1A induce migration and invasion of cancer cells via β1-integrin inactivation. Am J Cancer Res. 2020. 10. 11. 3990-4004
  • Motomichi Fujita, Manabu Sasada, Takuya Iyoda, Fumio Fukai. Involvement of Integrin-Activating Peptides Derived from Tenascin-C in Cancer Aggression and New Anticancer Strategy Using the Fibronectin-Derived Integrin-Inactivating Peptide. Molecules (Basel, Switzerland). 2020. 25. 14
  • Manabu Sasada, Takuya Iyoda, Tatsufumi Asayama, Yusuke Suenaga, Shunsuke Sakai, Naoya Kase, Hiroaki Kodama, Sana Yokoi, Yoichiro Isohama, Fumio Fukai. Inactivation of beta1 integrin induces proteasomal degradation of Myc oncoproteins. Oncotarget. 2019. 10. 48. 4960-4972
  • Kazuki Otsuka, Manabu Sasada, Y U Hirano, Yusuke Nohara, Takuya Iyoda, Yoshikazu Higami, Hiroaki Kodama, Fumio Fukai. Acyclic Retinoid Combined With Tenascin-C-derived Peptide Reduces the Malignant Phenotype of Neuroblastoma Cells Through N-Myc Degradation. Anticancer research. 2019. 39. 7. 3487-3492
more...
MISC (10):
Patents (1):
  • 細胞の転移又は浸潤抑制剤
Books (5):
  • Deregulation of platelet-derived growth factor (PDGF)-dependent cell proliferation through potentiated and sustained activation of β1-integrin, induced by tenascin-C-derived peptide TNIIIA2
    Nova publishers 2017 ISBN:9781536121780
  • Integrin-dependent cell regulation and its clinical application.
    Encyclopedia of Biocolloid and Biointerface Science 2016
  • Cell regulation through adhesion to the extracellular matrix via adhesion molecule, integrins -Therapeutic application of integrin activation-modulating peptides-
    ELSEVIER 2014
  • 人体機能学IV 薬理学テキスト
    福岡大学医学部薬理学教室 2010
  • Na+/Ca2+ 交換体を標的とした新規 Ca2+ 調節薬の開発
    メディカルドゥ・遺伝子医学MOOK 2009
Lectures and oral presentations  (168):
  • Abnormal signaling form ECM and macrophage foam cell formation.
    (2019)
  • Abnormal signaling from ECM and macrophage foam cell formation.
    (2019)
  • 多糖複合フィルムが異なる細胞種へ与える影響の評価
    (第39回日本バイオマテリアル学会大会 2017)
  • 熱プレス法により作製した多糖複合フィルムと細胞との相互作用の解析
    (第66回高分子討論会 2017)
  • テネイシンC由来インテグリン活性化ペプチドによる神経膠芽腫の悪性化進展およびそれに基づく新規治療法の提案
    (日本薬学会第137年会 2017)
more...
Education (2):
  • 2000 - 2005 Toho University molecular biology
  • - 2000 Toho University Biomolecular Science
Work history (5):
  • 2018/04 - 現在 Tokyo University of Science,Yamaguchi
  • 2016/04 - 2018/03 Tokyo University of Science Faculty of Pharmaceutical Sciences
  • 2011/04 - 2016/03 Tokyo University of Science. Faculty of Pharmaceutical Science; Assistant-Prof
  • 2007/10 - 2011/03 Fukuoka University, Faculty of Medicine; Assistant-Prof
  • 2005/04 - 2007/09 The University of Tennessee, College of Vet. Med.; Post-doc
Committee career (1):
  • 2007 - 日本トランスポーター研究会 幹事
Awards (1):
  • 2009/02 - 第38回 心脈管作動物質学会 若手研究奨励賞
Association Membership(s) (11):
THE JAPANESE PEPTIDE SOCIETY ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE ,  THE JAPANESE ASSOCIATION FOR MOLECULAR TARGET THERAPY OF CANCER ,  結合組織学会 ,  JAPANESE SOCIETY FOR IMMUNOLOGY ,  日本トランスポーター研究会 ,  日本循環薬理学会 ,  日本平滑筋学会 ,  日本心脈管作動物質学会 ,  日本分子生物学会
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