Rchr
J-GLOBAL ID:200901052001648398   Update date: May. 24, 2020

Iyoda Takuya

イヨダ タクヤ | Iyoda Takuya
Research field  (1): Pharmaceuticals - health and biochemistry
Research keywords  (1): innate immunity, cell adhesion, chronic inflammation, tumor, atherosclerosis
Research theme for competitive and other funds  (4):
  • 2011 - 2013 Molecular mechanism for malignant cell transformationinduced by a peptide derived from tenascin C through integrin activation
  • 2010 - 2012 Physiological role of calcium transport system regulated by phosphatidylinositol
  • 2008 - 2010 Analysis of physiological function of calcium transporters in epithelial cells and its pathological mechanisms
  • 2008 - 2009 Role of cation transporter in the regulation of macrophage function.
Papers (43):
  • Sasada M, Iyoda T, Asayama T, Suenaga Y, Sakai S, Kase N, Kodama H, Yokoi S, Isoyama Y, Fukai F. Inactivation of beta1 integrin induces proteasomal degradation of Myc oncoproteins. Oncotarget. 2019. 10. 48. 4960-4972
  • Otsuka K, Sasada M, Hirano Y, Nohara Y, Iyoda T, Higami Y, Kodama H, Fukai F. Acyclic Retinoid Combined with Tenascin-C-derived Peptide Reduces the Malignant Phenotype of Neuroblastoma Cells Through N-Myc Degradation. Anticancer research. 2019. 39. 7. 3487-3492
  • Fujita M, Yamamoto T, Iyoda T, Fujisawa T, Nagai R, Kudo C, Sasada M, Kodama H, Fukai F. Autocrine Production of PDGF Stimulated by the Tenascin-C-Derived Peptide TNIIIA2 Induces Hyper-Proliferation in Glioblastoma Cells. International Journal of Molecular Sciences. 2019. 20. 13. 3183
  • Fujita M, Yamamoto T, Iyoda T, Fujisawa T, Sasada M, Nagai R, Kudo C, Otsuka K, Kamiya S, Kodama H, Fukai F. Aggressive Progression in Glioblastoma Cells through Potentiated Activation of Integrin α5β1 by the Tenascin-C-Derived Peptide TNIIIA2. Molecular Cancer Therapeutics. 2019. 18. 9. 1251
  • Fujita M, Ito-Fujita Y, Iyoda T, Sasada M, Okada Y, Ishibashi K, Osawa T, Kodama H, Fukai F, Suzuki H. Peptide TNIIIA2 Derived from Tenascin-C Contributes to Malignant Progression in Colitis-Associated Colorectal Cancer via β1-Integrin Activation in Fibroblasts. International Journal of Molecular Sciences. 2019. 20. 11. 2752
more...
Books (3):
  • Deregulation of platelet-derived growth factor (PDGF)-dependent cell proliferation through potentiated and sustained activation of β1-integrin, induced by tenascin-C-derived peptide TNIIIA2
    Nova publishers 2017 ISBN:9781536121780
  • Integrin-dependent cell regulation and its clinical application.
    Encyclopedia of Biocolloid and Biointerface Science 2016
  • Cell regulation through adhesion to the extracellular matrix via adhesion molecule, integrins -Therapeutic application of integrin activation-modulating peptides-
    ELSEVIER 2014
Lectures and oral presentations  (34):
  • Effect of Anionic Polysaccharides of Polysaccharide Composite Films on Adhesion and Proliferation of Cells
    (The 11th SPSJ International Polymer Conference (IPC2016) 2016)
  • 大腸発がんおよびその悪性化進展におけるテネイシン C の関与
    (日本薬学会 第136年会 2016)
  • ROLE OF THE TNIIIA2 SITE IN TENASCIN-C IN THE PROGRESSION OF ATHEROSCLEROSIS
    (The 4th International Postgraduate Conference on Pharmaceutical Sciences 2016 (iPoPS 2016) 2016)
  • MEMBRANE EXPRESSION OF EUKARYOTIC PROTEIN ELONGATION FACTOR 1A AND ITS PHYSIOLOGICAL ROLE
    (The 4th International Postgraduate Conference on Pharmaceutical Sciences 2016 (iPoPS 2016) 2016)
  • Evaluation of proliferation of fibroblasts on chondroitin sulfate/chitosan composite films prepared by hot press techniques
    (The International Chemical Congress of Pacific Basin Societies (Pacifichem 2015) 2015)
more...
Education (2):
  • 2000 - 2005 Toho University Graduate School, Division of Science molecular biology
  • - 2000 Toho University Faculty of Science Biomolecular Science
Work history (5):
  • 2018/04 - 現在 Tokyo University of Science,Yamaguchi
  • 2016/04 - 2018/03 Tokyo University of Science
  • 2011/04 - 2016/03 Tokyo University of Science. Faculty of Pharmaceutical Science; Assistant-Prof
  • 2007/10 - 2011/03 Fukuoka University, Faculty of Medicine; Assistant-Prof
  • 2005/04 - 2007/09 The University of Tennessee, College of Vet. Med.; Post-doc
Association Membership(s) (5):
THE JAPANESE PEPTIDE SOCIETY ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE ,  THE JAPANESE ASSOCIATION FOR MOLECULAR TARGET THERAPY OF CANCER ,  JAPANESE SOCIETY FOR IMMUNOLOGY
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