HIYAMA EISO

2015 - 2018 Cancer fluid biopsy for childhood malignancies using one cell analysis

2014 - 2017 Nerve growth factor expression and perineural invasion in bile carcinoma

2015 - 2016 Effects of genomic damage by chemo-radiation therapy during childhood for secondary malignancy and genetic inheritance

2014 - 2016 Development of treatment strategy for rhabdomyosarcoma based on control of cancer stem cell proliferation

2013 - 2016 Development of non-invasive diagnosis and novel therapies for pediatric solid tumor

2013 - 2016 Molecular analysis for new therapeutic strategies in global cooperative clinical study for childhood hepatic tumors

2014 - 2015 Analysis of genomic aberrations, risk of secondary cancer development and, hereditary effects by irradiation and chemotherapy in children

2012 - 2015 Detection of molecular targets for childhood cancers using genomics and cellomics: targeting for cancer stem cells

2011 - 2015 Survey of childhood liver tumors in Asian area and infrastructural development of international collaboration study by Japanese study group for pediatric liver tumors (JPLT)

2013 - 2014 Genomic aberrations by chemoradiotherapy in children and its transfer to next generation

2012 - 2012 Genomic mutations and their transmission in survivors of childhoodcancer treated with radiation and chemotherapy

2010 - 2012 Molecular analysis for developing the newtargeting therapy in Japanese Pediatric Liver Tumor study group

2009 - 2011 Elucidation of development mechanism and molecular targets in neuroblastoma and hepatoblastoma using genomics and cellomics

2009 - 2011 Analysis of telomere and telomerase activation mechanism in pancreatic neoplasms for molecularly targeted therapy

2008 - 2010 Surveillance of current incidence and infrastructure development of international collaboration for childhood liver cancers by Japanese study group for pediatric liver tumor

2008 - 2010 Target therapy in bone and soft tissue sarcomas using magnetic liposomal telomerase inhibitor under an external magnetic force

2008 - 2009 日本小児肝がんスタディグループにおける治療戦略のための分子基盤の構築

2007 - 2009 molecular analyses and translational research of neuroblastoma based upon a clinical trial of the nation-wide group study

2008 - 2008 ヒト骨髄間葉系幹細胞から樹立した細胞株:ヒトがん幹細胞株か?

2007 - 2008 神経芽腫のがん幹細胞研究:分化・退縮と発生・増殖・進展の二極化規定因子か?

2007 - 2007 ヒト骨髄間葉系幹細胞由来の不死化細胞とがん幹細胞

2006 - 2007 Study of genetic of atomic bomb radiation by using high density DNA microarray based-CGH

2004 - 2006 Development of novel diagnostic and therapeutic strategies of hepatoblastoma through multicenter cooperative study

2004 - 2005 Does hepatic regeneration promotes engraftment of intraportally transplanted islet cells?

2004 - 2005 Methylation analysis of caspase 8 in utilizing methylation microarray on neuroblastoma patients

2003 - 2004 Microarray analysis for detecting biological characteristics in neuroblastoma

2002 - 2003 Study of Genetic effects of A-bomb radiation using microarray CGH

2002 - 2003 Telomere as a possible marker for aging of cardiovascular system

2000 - 2003 ANALYSIS OF BIOLOGICAL PROGNOSTIC FACTOR TO ESTABLISH TREATMENT FOR PEDIATRIC LIVER TUMOR BY GROUP STUDY

2001 - 2002 Microarray analysis for detecting biological characteristics in neuroblastoma

2001 - 2001 膵癌に対するハンマーヘッド型リボザイムを用いたテロメラーゼ活性抑制療法の試み

2001 - 2001 神経芽細胞腫のアポトーシス誘導を制御するカスパーゼ8の解析

2000 - 2001 A STUDY ON CARCINOGENESIS OF THE PANCREATIC CANCER AND BIOMARKERS FOR ERALY DIAGNOSIS OF THE PANCREATIC CANCER

2000 - 2001 Study of telomere and telomerase for the identification of regression or maturation mechanisms in neuroblastoma

1999 - 2000 Study of telomerase as a useful target for diagnosis and therapy of neuroblastoma with the aim of clinical application

1999 - 1999 がんの早期診断及び悪性度診断としてのテロメラーゼの臨床応用

1998 - 1998 神経芽細胞腫の一番染色体短腕上の有力な3つの癌抑制遺伝子の解明

1997 - 1998 APPLICATION OF TELOMERE LENGTH AND TELOMERASE ACTIVITY IN SURGERY : EARLY DETECTION OF PREVENTION OF POSTOPERATIVE RECURRENCE AND METASTASIS

1997 - 1998 神経芽細胞腫の生物学的特性の統合的解析-有用なバイオマーカーの検索-

1997 - 1997 がんの早期診断及び悪性度診断としてのテロメア・テロメラーゼ

1996 - 1997 Telomerase Activity of the Blood Cells in Patients with Myeloproliferative Disorders in Childhood

1996 - 1996 Basic studies for telomerase as a novel target for cancer diganosis and therapy

1996 - 1996 ヒルシュスプリング病の遺伝子解析

1995 - 1995 神経芽細胞腫のテロメラーゼ-診断・治療の新しいターゲット-

1995 - 1995 消化器癌のテロメアとテロメラーゼ 一診断治療の新しいターゲット

1994 - 1994 重症手術侵襲時(SIRS)におけるサイトカインネットワークの解析

1994 - 1994 分子生物的アプローチによる神経芽腫マススクリーニングの効果判定

1993 - 1993 神経芽細胞腫における癌抑制遺伝子へのアプローチ-悪性度との関連から-

1992 - 1993 The study with rapid detection for the toxins of Methicillin-resistant Staphylococcus aureus and with the action of the toxins

1992 - 1992 神経芽細胞腫の分子生物学的特性の特析-悪性度,自然退縮とテロメアの関連について-

1991 - 1991 神経芽細胞腫の新しい予後因子の解析-分子生物学的な多因子解析-

1990 - 1990 手術侵襲と局所食細胞機能についての実験的研究