Rchr
J-GLOBAL ID:200901052947218431   Update date: Sep. 28, 2024

Hattori Masakazu

ハットリ マサカズ | Hattori Masakazu
Affiliation and department:
Job title: Professor
Research field  (2): Immunology ,  Cell biology
Research keywords  (3): 免疫学 ,  Cell Bioligy ,  Immunology
Research theme for competitive and other funds  (6):
  • 1998 - 1998 酸化的修飾がシグナルとなるユビキチン依存性蛋白分解の細胞機能制御における役割
  • 1997 - 1997 酸化的修飾がシグナルとなるユビキチン依存性蛋白分解の細胞機能制御における役割
  • 1986 - リンパ・造血系細胞の分化・増殖制御機構に関する研究
  • 1986 - Study on the regulation of differentiation and cell-growth in lymphocytes and hematopoietic cells.
  • SPA-1阻害薬のスクリーニング
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Papers (80):
  • Yuji Fukushima, Ryuji Ueno, Nagahiro Minato, Masakazu Hattori. Senescence-Associated T cells in Immunosenescence and Diseases. International immunology. 2024
  • Yuji Fukushima, Nagahiro Minato, Masakazu Hattori. Protocol for the isolation of mouse senescence-associated CD4+ T cells using flow cytometry and functional assays. STAR protocols. 2023. 4. 3. 102472-102472
  • Yuji Fukushima, Keiko Sakamoto, Michiyuki Matsuda, Yasunobu Yoshikai, Hideo Yagita, Daisuke Kitamura, Misaki Chihara, Nagahiro Minato, Masakazu Hattori. cis interaction of CD153 with TCR/CD3 is crucial for the pathogenic activation of senescence-associated T cells. Cell reports. 2022. 40. 12. 111373-111373
  • Yuki Sato, Akiko Oguchi, Yuji Fukushima, Kyoko Masuda, Naoya Toriu, Keisuke Taniguchi, Takahisa Yoshikawa, Xiaotong Cui, Makiko Kondo, Takeshi Hosoi, et al. CD153/CD30 signaling promotes age-dependent tertiary lymphoid tissue expansion and kidney injury. The Journal of clinical investigation. 2022. 132. 2
  • Mariko Nishie, Eiji Suzuki, Masakazu Hattori, Kosuke Kawaguch, Tatsuki R. Kataoka, Masahiro Hirata, Fengling Pu, Takeshi Kotake, Moe Tsuda, Ayane Yamaguchi, et al. Downregulated ATP6V1B1 expression acidifies the intracellular environment of cancer cells leading to resistance to antibody-dependent cellular cytotoxicity. Cancer Immunology, Immunotherapy. 2020
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MISC (16):
  • Mariko Nishie, Eiji Suzuki, Kosuke Kawaguchi, Keiko Sakamoto, Yuji Fukushima, Masakazu Hattori, Tomoharu Sugie, Masakazu Toi. Downregulation of ATP6V1B1 in HER2-overexpressing human breast cancer cell line leads resistance against trastuzumab-mediated antibody-dependent cellular cytotoxicity. CANCER RESEARCH. 2015. 75
  • 林田京子, 服部雅一, 梶野喜一, WALLACE Maura, MORRISON Ivan, 杉本千尋. タイレリア感染による宿主細胞アポトーシス回避機構の解明. 日本獣医学会学術集会講演要旨集. 2012. 153rd. 110
  • Kenichiro Shimatani, Yasuhiro Nakashima, Masakazu Hattori, Yoko Hamazaki, Nagahiro Minato. PD-1(+) memory phenotype CD4(+) T cells expressing C/EBP alpha underlie T cell immunodepression in senescence and leukemia. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009. 106. 37. 15807-15812
  • 米谷 耕平, 新田 剛, 服部 雅一, 竹田 潤二, 高浜 洋介, 湊 長博. 胸腺内T細胞分化における低分子量G蛋白質,Rap1の役割. 日本免疫学会総会・学術集会記録. 2004. 34. 316-316
  • 石田 大輔, 米谷 耕平, 服部 雅一, 湊 長博. SPA-1遺伝子破壊マウスにおける骨髄増殖性疾患の発症. 日本癌学会総会記事. 2004. 63回. 406-406
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Patents (3):
  • 抗原特異的モノクローナル抗体産生ハイブリドーマの作成方法及び抗原特異的モノクローナル抗体の製造作成
  • 粘膜,上皮および鼓膜の少なくとも一つの再生材および再生評価方法
  • SPA-1蛋白質及びそれをコードする遺伝子
Lectures and oral presentations  (1):
  • 老化関連T細胞の誘導メカニズムとその制御
    (日本炎症・再生医学会 2017)
Education (4):
  • - 1984 Hokkaido University
  • - 1984 Hokkaido University Graduate School, Division of Veterinary Medicine
  • - 1981 Hokkaido University School of Veterinary Medicine
  • - 1981 Hokkaido University Faculty of Veterinary Medicine
Professional career (1):
  • Doctor of Veterinary Science (Hokkaido University)
Work history (8):
  • 2022/04 - 現在 Kyoto University
  • 2016/04 - 2022/03 Kyoto University
  • 2011/04 - 2016/03 Kyoto University
  • 2008/07 - 2011/03 Kitasato University
  • 1997 - 2008/06 Kyoto University
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Association Membership(s) (3):
分子生物学会 ,  癌学会 ,  免疫学会
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