Rchr
J-GLOBAL ID：200901053258818762   Update date: Oct. 22, 2024

SAKAGUCHI Masayoshi

サカグチ マサヨシ | SAKAGUCHI Masayoshi
Affiliation and department：
Kogakuin University School of Advanced Engineering Department of Chemistry and Life Science

About Kogakuin University School of Advanced Engineering Department of Chemistry and Life Science


Job title： Associate Professor
Research field  (4)： Functional solid-state chemistry ,  Biochemistry ,  Structural biochemistry ,  Applied biochemistry
Research keywords  (10)： serine protease ,  chitinase ,  bacteria ,  archaea ,  glucoaymase ,  trehalase ,  GH15 family enzyme ,  carbohydrate-hydrolyzing enzyme ,  characterization ,  enzyme chemistry
Research theme for competitive and other funds  (9)：
  • 2017 - 2020 Functional analysis of archaeal trehalases and attempt of their properties for novel oligosaccharides production
  • 2002 - 2012 細菌由来新規グルコアミラーゼのクローニングと発現、及び特性解析
  • 2002 - 2012 Cloning, expression, and characterization of novel glucoamylase from Caulobacter crescentus CB15
  • 1998 - 2012 細菌グルコアミラーゼの機能と構造の解析
  • 1998 - 2012 Analysis of function and structure in bacterial glucoamylase
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Papers (29)：
  • Tabata, E., Itoigawa, A., Koinuma, T., Tayama, H., Kashimura, A., et al. Noninsect-based diet leads to structural and functional changes of acidic chitinase in carnivora. Molecular Biology and Evolution. 2022. 39. 1
  • Sakaguchi, M., Mukaeda, H., Kume, A., Toyoda, Y., Sakoh, T., et al. Evaluation of the roles of hydrophobic residues in the N-terminal region of archaeal trehalase in its folding. Applied Microbiology and Biotechnology. 2021. 105. 8. 3181-3194
  • Kimura, M., Watanabe, T., Sekine, K., Ishizuka, H., Ikejiri, A., et al. Comparative functional analysis between human and mouse chitotriosidase: Substitution at amino acid 218 modulates the chitinolytic and transglycosylation activity. International Journal of Biological Macromolecules. 2020. 164. 2895-2902
  • Ohno, M., Miyazaki, M., Kimura, M., Minowa, Y., Sakaguchi, M., et al. Characterization of mouse di-N-acetylchitobiase that can degrade chitin-oligosaccharides. Bioscience, Biotechnology, and Biochemistry. 2020. 84. 12. 2499-2507
  • Kimura, M., Umeyama, T., Wakita, S., Okawa, K., Sakaguchi, M., et al. Quantification of chitooligosaccharides by FACE method: determination of combinatory effects of mouse chitinases. MethodsX, 7: 100881, 2020. 2020. 7. 100881-100881
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MISC (27)：
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Books (2)：
  • Handbook of Proteolytic Enzymes, 3rd Edition
    Academic press, ELSEVIER Ltd 2012 ISBN:9780123822192
  • Handbook of Proteolytic Enzymes, 3rd Edition
    Academic press, ELSEVIER Ltd 2012 ISBN:9780123822192
Lectures and oral presentations  (260)：
  • 非昆虫ベースの食餌は,肉食性動物の酸性キチナーゼの構造と機能を変化させる
    (日本農芸化学会 2022年度(令和4年度)[京都]大会 2022)
  • ネコ酸性キチナーゼ偽遺伝子の活性化
    (日本農芸化学会 2022年度(令和4年度)[京都]大会 2022)
  • 好酸性アーケア<I>Thermoplasma volcanium</I> GH15 トレハラーゼの立体構造解析
    (日本農芸化学会 2022年度(令和4年度)[京都]大会 2022)
  • ヒトとマウスキトトリオシダーゼの活性とアミノ酸配列比較
    (第35回日本キチン・キトサン学会大会 2021)
  • 食肉目動物の食性と酸性キチナーゼの機能に関する研究
    (第35回日本キチン・キトサン学会大会 2021)
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Education (2)：
  • 1993 - 1995 Tokyo University of Agriculture and Technology Graduate School, Division of Agriculture
  • 1989 - 1993 Tokyo University of Agriculture and Technology Faculty of Agriculture
Professional career (3)：
  • 学士(農学) (Tokyo University of Agriculture and Technology)
  • 修士(農学) (Tokyo University of Agriculture and Technology)
  • Doctor of Philosophy in Engineering (Kogakuin University)
Work history (5)：
  • 2017/04 - 現在 工学院大学先進工学部 生命化学科 准教授
  • 2015/04 - 2017/03 工学院大学先進工学部 生命化学科 講師
  • 2016/04 - 2016/09 東京農工大学農学府農学部 非常勤講師「応用生物科学特別講義I」
  • 2009/04 - 2015/03 Kogakuin University Faculty of Engineering, Department of Applied Chemistry
  • 1995/04 - 2009/03 Kogakuin University Faculty of Engineering, Department of Applied Chemistry
Association Membership(s) (3)：
日本化学会 ,  日本農芸化学会 ,  日本応用糖質科学会
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