Rchr

J-GLOBAL ID：200901053323611801 Update date: Sep. 26, 2024

Akihiro Kawauchi

カワウチアキヒロ | Akihiro Kawauchi

Affiliation and department：
Job title： Professor

Research field (1)： Urology

Research keywords (2)：泌尿器科学 , Urology

Research theme for competitive and other funds (57)：

2022 - 2027 脳内炎症に着目した泌尿器癌悪液質の新規診断・治療法の開発
2022 - 2025 羊膜上清及び脂肪由来幹細胞を播種した生体吸収性2層足場材料による機能的膀胱再生
2021 - 2024 抗癌標的分子GGCT阻害によるグルタチオン関連分子変動の網羅的解明
2020 - 2023 サルコペニアと疲労の関連に着目した高齢癌患者の治療指針となるバイオマーカーの探索
2020 - 2023 Ureter regeneration using bioabsorbable two-layered scaffold with a newly developed gel material to prevent urine leakage

2018 - 2021 Development of anticancer therapy with the GGCT inhibitor for urothelial carcinoma

2017 - 2020 Elucidation of the mechanism of antitumor effect in inhibition of GGCT expression using integrated omics analysis

2017 - 2019 The elucidation of molecular mechanism of chromosomal translocation in prostate cancer and application to new treatment

2016 - 2019 Development of novel treatment for prostate cancer with the specific peptide which target to prostate cancer tissue

2015 - 2018 The exploratory research of biomarkers of renal cell carcinomas for therapeutic drugs based on the evidence of global transcriptome analysis.

2015 - 2018 Development of anticancer therapy for urological malignancy using GGCT inhibitors

2015 - 2018 Functional bladder regeneration with tissue engineering urothelium using human amnion: a study on dogs

2014 - 2017 Regulatory T cells in intravesical BCG therapy for non-muscle invasive bladder cancer

2013 - 2016 Development of comprehensive seed implantation technique aiming for overcoming pubic bone interference during permanent brachytherapy in men with prostate cancer.

2013 - 2016 Urinary reconstruction using the cultivated oral mucosal epithelial sheet on amniotic membrane matrix.

2012 - 2015 Screen for novel therapeutic target of prostate cancer patient using drosophila as model.

2012 - 2015 Development of anticancer therapy with GGCT targeting siRNA for urothelial tumor

2012 - 2015 The effect of Nitric Oxide (NO) treatment on renal cell cancer

2012 - 2015 Identification of taxane-binding protein by utilizing magnetic beads to clarify the molecular mechanism how to develop taxane-resistance in prostate cancer

2012 - 2014 Comparative analysis of erectile dysfunction and neural peptide in the central nervous system using erectile dysfunction model rats

2011 - 2014 Molecular and functional analysis of novel androgen receptor co-repressor in testicular cancer

2011 - 2013 Development of interactive mapping system for focal therapy of prostate cancer

2011 - 2013 Identification of cancer testis antigens as a prognostic marker for testicular tumor

2010 - 2011 The development of novel molecular therapeutic agents targeting ion transporters for the treatment of hormone refractory prostate cancer

2009 - 2011 Development of dynamic 3-D surgical navigation using body-GPS

2009 - 2011 Development of the template prostate biopsy method with the three-dimensional space position recognition system

2009 - 2011 Urinary reconstruction using the cultivated oral mucosal epithelial sheet

2009 - 2010 前立腺MRIと超音波の融合3次元ガイダンスによる高精度前立腺針生検法の開発

2007 - 2008 Imaging analysis in men with lower urinary tract symptoms using transrectal elastography

2006 - 2007 Molecular targeted gene therapy against hormone-refractoty prostate cancer by new ultrasonic gene transfection

2006 - 2007 Regeneration of human cavernous smooth Muscle cell for erectile dysfunction

2006 - 2007 ムスカリン受容体ノックアウトマウスの排尿障害とその代謝機能の分子生物学的解析

2005 - 2006 Development for analytic system of real-time voiding manner using the small-type trasnrectal probe

2005 - 2006 DNA修復遺伝子欠損細胞を用いたDNA損傷抗癌剤感受性の網羅的検討とその臨床応用

2004 - 2006 Analysis of mechanisms of the resistance of cisplatin in refractory or relapsed germ cell tumors

2003 - 2004 Study on DNA Metabolizing Enzymes as Molecular Theraputic Targets in Renal Cell Carcinoma

2003 - 2004 Electrochemo-gene therapy of Cancer using Epstein Barr virus-plasmid vector ; Intratumoral delivery of Interleukin-12 gene and bleomycin induce therapeutic immunity and suppressed subcutaneous and metastatic melanomas in mice

2003 - 2004 Clarification of the sexual dysfunction by diabetes

2003 - 2004 術後および各種疾患による神経障害に対する再生用デバイスを用いた神経再生

2003 - 2004 前立腺の前方筋線維性間質(AFMS)の機能解明におけるα1およびM受容体の意義

2002 - 2004 Analysis of tumor suppressor gene in refractory or relapsed germ cell tumors and its therapeutic application

2002 - 2003 Real-time imaging analysis of androgen receptor function in hormone refractory Prostate cancer

2002 - 2003 インターフェロンβ・リポソーム遺伝子治療製剤を用いた腎癌に対する遺伝子治療の開発

2001 - 2002 Clarification of transmission mechanism of urinary sensation in pontine micturition center and central effect of drugs for voiding dysfunction.

2001 - 2002 Antitumoral effect of selective cycloxygenase-2 inhibitor against urological cancer

2001 - 2002 Effects of insulin - like growth factor binding protein-3 (IGFBP-3) on diabetes - induced erectile dysfunction (ED)

2000 - 2001 Identification of cisplatin-resistant gene in bladder cancer by DNA chip

2000 - 2001 Effects of acupuncture to the sacral segment on the brainstem micturition center in rats

1995 - 1996 Development of therapeutic apparatus for incontinence with urinary bladder training by mechanical acupuncture stimulation triggered by biophysical information.

1994 - 1994 睡眠中に膀胱内圧測定を行って小児の神経因性膀胱を確実に診断する方法の開発

1989 - 1991 Development of Percutaneous Cryosurgery for Renal Tumor

神経生理学

泌尿器腫瘍学

Endourology

小児泌尿器科

Pediatric urology

Nocturnal ennresis

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Papers (340)：

Yuki Okinaka, Susumu Kageyama, Toshiyuki Goto, Masahiro Sugimoto, Atsumi Tomita, Yumi Aizawa, Kenichi Kobayashi, Akinori Wada, Akihiro Kawauchi, Yosky Kataoka. Metabolomic profiling of cancer-related fatigue involved in cachexia and chemotherapy. Scientific reports. 2024. 14. 1. 8329-8329
竹内佳代, 城文泰, 奥村勇太, 菊井亮輔, 田中翔, 中川翔太, 馬塲雅人, 草場拓人, 窪田成寿, 永澤誠之, et al. 難治性の膀胱直腸瘻に対してYork-Mason法が有効であった1例. 泌尿器科紀要. 2023. 69. 12. 374-375
永澤誠之, 片山真由果, 長船崇, 七里泰正, 河内明宏. 上部尿路上皮癌に対するロボット支援腹腔鏡下腎尿管全摘術の初期経験. 日本泌尿器内視鏡・ロボティクス学会総会. 2023. 37回. P-12
上仁数義, 中川翔太, 城文泰, 窪田成寿, 和田晃典, 小林憲市, 吉田哲也, 影山進, 河内明宏. 思春期以降の膀胱尿管逆流に対する腹腔鏡下膀胱内手術. 日本泌尿器内視鏡・ロボティクス学会総会. 2023. 37回. AV-1
上仁数義, 小林憲市, 中川翔太, 森友莉, 中村真俊, 永澤誠之, 河内明宏. 『小児泌尿器腹腔鏡下手術・ロボット支援手術の近未来-必然と蓋然-』腎盂尿管移行部通過障害. 日本小児泌尿器科学会雑誌. 2023. 32. 2. 231-231

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MISC (1,583)：

上仁数義, 中川翔太, 河内明宏. 【症例から考える小児泌尿器疾患:小児病院での私のみかた】学童期によくみる泌尿器疾患学童期の夜尿症(2). 小児科診療. 2022. 85. 3. 373-379
中村真俊, 草場拓人, 森友莉, 奥末理知, 出口真央, 小崎成昭, 和田晃典, 富田圭司, 村井亮介, 水流輝彦, et al. 腎平滑筋肉腫の1例. 泌尿器科紀要. 2022. 68. 1. 24-24
前田航規, 長船崇, 益田良賢, 中川翔太, 河内明宏. BEP療法でSyndrome of inappropriate secretion of antidiuretic hormone(SIADH)を来たした精巣癌の1例. 泌尿器科紀要. 2022. 68. 1. 26-26
成田充弘, 草場拓人, 吉田哲也, 影山進, 河内明宏. 高難度の腹腔鏡下副腎摘除・後腹膜腫瘍摘除-困難例へのコツと対応- 当院における腹腔鏡下副腎摘除術における手術困難症例に関しての検討. 日本内視鏡外科学会雑誌. 2021. 26. 7. WS12-1
中川翔太, 上仁数義, 吉田哲也, 影山進, 成田充弘, 河内明宏. 当院におけるロボット支援腹腔鏡下腎盂形成術の初期成績. 日本内視鏡外科学会雑誌. 2021. 26. 7. MO234-6

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Books (1)：

膀胱尿管逆流に対する腹腔鏡下膀胱内手術。VI小児泌尿器科手術新版泌尿器科周術期管理のすべて
メジカルビュー社 2013

Education (4)：

- 1989 Kyoto Prefectural University of Medicine
- 1989 Kyoto Prefectural University of Medicine Graduate School, Division of Medicine
- 1984 Kyoto Prefectural University of Medicine
- 1984 Kyoto Prefectural University of Medicine Faculty of Medicine

Professional career (2)：

Doctor of Medicine
博士 (京都府立医科大学)

Work history (2)：

Shiga University of Medical Science
Kyoto Prefectural University of Medicine

Awards (1)：

2005 - 第92回日本泌尿器科学会総会賞

Association Membership(s) (14)：

日本泌尿器内視鏡・ロボティクス学会 , 国際泌尿器科学会 , 国際小児尿禁制学会 , 日本透析医学会 , 日本性機能学会 , 日本アンドロロジー学会 , 日本癌治療学会 , 日本内視鏡外科学会 , 日本癌学会 , 日本小児泌尿器科学会 , 日本夜尿症学会 , 日本睡眠学会 , 日本超音波医学会 , 日本泌尿器科学会

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