Rchr
J-GLOBAL ID：200901053375954049
Update date: Jul. 26, 2023
KEIKO MUGURUMA
ムグルマ ケイコ | KEIKO MUGURUMA
Affiliation and department：
Job title：
Professor
Research field (3)：
Nervous system function
, Developmental biology
, Neuroscience - general
Research keywords (9)：
神経疾患
, organoid
, neuroscience
, cerebellar development
, ES cells
, iPS cells
, histogenesis
, neural development
, stem cell
Papers (40)：
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Kodai Kume, Takashi Kurashige, Keiko Muguruma, Hiroyuki Morino, Yui Tada, Mai Kikumoto, Tatsuo Miyamoto, Silvia Natsuko Akutsu, Yukiko Matsuda, Shinya Matsuura, et al. CGG repeat expansion in LRP12 in amyotrophic lateral sclerosis. American journal of human genetics. 2023
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Hajime Ozaki, Hidetaka Suga, Mayu Sakakibara, Mika Soen, Natsuki Miyake, Tsutomu Miwata, Shiori Taga, Takashi Nagai, Mayuko Kano, Kazuki Mitsumoto, et al. Differentiation of human induced pluripotent stem cells into hypothalamic vasopressin neurons with minimal exogenous signals and partial conversion to the naive state. Scientific reports. 2022. 12. 1. 17381-17381
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Mariko Taniguchi-Ikeda, Michiyo Koyanagi-Aoi, Tatsuo Maruyama, Toru Takaori, Akiko Hosoya, Hiroyuki Tezuka, Shotaro Nagase, Takuma Ishihara, Taisuke Kadoshima, Keiko Muguruma, et al. Restoration of the defect in radial glial fiber migration and cortical plate organization in a brain organoid model of Fukuyama muscular dystrophy. iScience. 2021. 24. 10. 103140-103140
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蟹江 慶太郎, 井口 元三, 伊藤 剛, 喜多山 秀一, 六車 恵子, 坂東 弘教, 松本 隆作, 山本 雅昭, 福岡 秀規, 金子 新, et al. 疾患iPS細胞/抗原特異的T細胞を用いた抗PIT-1下垂体炎疾患モデルの樹立. 日本内分泌学会雑誌. 2021. 97. 1. 262-262
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Atsushi Tamada, Shoji Watanabe, Keiko Muguruma. Investigating developmental and disease mechanisms of the cerebellum with pluripotent stem cells. MOLECULAR AND CELLULAR NEUROSCIENCE. 2020. 107
ｍore...
MISC (30)：
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Toshiya Kimura, Keiko Muguruma. iPS cell technologies toward overcoming neurological diseases. Folia Pharmacologica Japonica. 2023. 158. 1. 57-63
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六車恵子. オルガノイドで解き明かすヒト脳の神秘. 週刊医学界新聞. 2022. 3492
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玉田篤史, 木村俊哉, 次山ルシラ絵美子, 六車恵子. 脳オルガノイドを用いたヒト脳の発生・疾患の理解. 生体の科学. 2022. 73. 4. 343-347
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MUGURUMA KEIKO. iPS細胞を用いた小脳の発生と病態の解明. Clinical Neuroscience. 2019. 37. 8. 1011-1014
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蟹江 慶太郎, 井口 元三, 坂東 弘教, 松本 隆作, 六車 恵子, 志智 大城, 藤田 泰功, 隅田 健太郎, 福岡 秀規, 小川 渉, et al. 疾患iPS細胞を用いた抗PIT-1抗体症候群疾患モデルの樹立. 日本内分泌学会雑誌. 2019. 95. 1. 390-390
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Books (4)：
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Cerebellum as a CNS Hub
Springer 2021 ISBN:9783030758165
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運動失調のみかた、考え方 小脳と脊髄小脳変性症
中外医学社 2017
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Organ Regeneration based on developmental biology
Springer Nature 2017
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iPS細胞の安全・高品質な作成技術
技術情報協会 2016
Lectures and oral presentations (41)：
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11. Construction of brain tissues from human pluripotent stem cells for investigating oof neurological disease and brain development
(The 95th Annual Meeting of the Japanese Pharmacological Society 2022)
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SCD•MSAの小脳作製の研究
(近畿SCD・MSA友の会創立40周年記念iPS細胞医療講演会 2021)
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iPS細胞を用いた神経疾患研究
(第117回日本精神神経学会学術総会 2021)
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iPS細胞を用いた疾患研究
(第214回加多乃会勉強会 2021)
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Modeling of human cerebellar development and diseases with pluripotent stem cell-derived brain organoids
(The 44th Annual Meeting of the Japan Neuroscience Society The 1st CTK International Meeting 2021)
ｍore...
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