Rchr
J-GLOBAL ID:200901054331079821
Update date: Sep. 02, 2024
Karata Shoichiro
クラタ ショウイチロウ | Karata Shoichiro
Affiliation and department:
Job title:
Professor
Homepage URL (1):
http://www.pharm.tohoku.ac.jp/~seimei/seimei_original.html
Research field (4):
Molecular biology
, Developmental biology
, Pharmacology
, Pharmaceuticals - health and biochemistry
Research keywords (5):
peptidoglycan
, transdetermination
, pathogen recognition
, organ identity
, innate immunity
Research theme for competitive and other funds (41):
- 1990 - 現在 Determination of organ identity
- 1990 - 現在 Innate immunity
- 2022 - 2025 自然免疫受容体TollとGyc76Cのリガンドアイソフォームの発現による免疫調節
- 2021 - 2023 Homeostasis through regulation of gut microbiota by the nervous system
- 2019 - 2022 Regulation of humoral and cellular immune responses by innate immune receptor Gyc76C in Drosophila
- 2018 - 2020 Neurons regulating immune system
- 2016 - 2019 Studies of modulation mechanisms of NF-kB signaling by novel cGMP pathway
- 2015 - 2017 RNA virus regulation based on symbiotic bacteria
- 2014 - 2016 細胞内共生細菌による宿主へのウイルス耐性付与機構の解明
- 2013 - 2015 Function of simjang that enhances transdetermination of Drosophila imaginal discs
- 2012 - 2015 Analysis of novel cGMP pathway regulating innate immune responses
- 2009 - 2014 Homeostatic inflammation: Molecular basis and dysregulation
- 2009 - 2014 HOMEOSTATIC INFLAMMATION IN DROSOPHILA
- 2011 - 2012 Functional analysis of epigenetic regulation in Drosophilaintestinal homeostasis
- 2009 - 2011 Study of induction mechanisms of autophagy in innate immunity
- 2009 - 2011 Basic study on mechanisms of metacyclogenesis-related vector-parasite relationships
- 2009 - 2009 ペプチドグリカン認識蛋白質(PGRP)-LEによる細胞内寄生細菌の認識と排除機構
- 2009 - 2009 病原体センサーによるオートファジー誘導機構の解明
- 2009 - 2009 細胞内細菌感染に対抗するオートファジー誘導機構
- 2008 - 2009 クロマチン結合タンパク質Winged eyeによるdecoding制御
- 2007 - 2008 ペプチドグリカン認識蛋白質(PGRP)-LEによる細胞内寄生細菌の認識と排除機構
- 2006 - 2007 ショウジョウバエゲノム機能解析により得られた器官改変を誘導する遺伝子群の解析
- 2006 - 2007 クロマチン結合タンパク質Winged eyeによるdecoding制御
- 2001 - 2006 自然免疫による異物認識の分子基盤の研究成果とりまとめ
- 2001 - 2005 Signaling cascade and network regulating innate immunity
- 2002 - 2003 The role of Notch signaling in the transdetermination
- 2002 - 2003 新しい機能獲得変異体スクリーニングによる自然免疫の分子機構の解明
- 2001 - 2003 Identificaion of compounds acting innate immunity using a newly established in vitro screen
- 2001 - 2001 ショウジョウバエの器官アイデンティティーを決定するプログラムの網羅的解析
- 2000 - 2001 Construction of New Biological Screening System Using Insects and Search for Biologically Active Substances from Natural Sources
- 2000 - 2001 Development of Novel Antimalarial Drugs Based on Plant Alkaloids
- 2000 - 2001 自然免疫系を制御する脂質メディエーター
- 2000 - 2000 Notchシグナリングを中心とした器官アイデンティティーの決定機構の解析
- 2000 - 2000 ショウジョウバエの器官アイデンティティーを決定するプログラムの網羅的解析
- 1999 - 1999 昆虫複眼のマスターコントロール遺伝子eyelessによる器官特異性の決定機構
- 1999 - 1999 Notchシグナリングと器官アイデンティティーの確立
- 1998 - 1999 The common mechanisms for the determination of organ identity
- 1998 - 1998 Notchシグナリングを中心とした動物appendage形成の基本的共通機構
- 1998 - 1998 昆虫複眼のマスターコントロール遺伝子eyelessの発現制御機構
- 1992 - 1994 Defense mechanism of insect (Sarcophaga peregrina)
- 1990 - 1990 センチニクバエ蛹化時における自己細胞と自己由来非自己細胞の識別機構
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Papers (167):
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Naoyuki Fuse, Haruka Hashiba, Kentaro Ishibashi, Takuro Suzuki, Quang-Dat Nguyen, Kiho Fujii, Wakako Ikeda-Ohtsubo, Haruki Kitazawa, Hiromu Tanimoto, Shoichiro Kurata. Neural control of redox response and microbiota-triggered inflammation in Drosophila gut. Frontiers in Immunology. 2023. 14
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Stefania Dentice Maidana, Mariano Elean, Kohtaro Fukuyama, Yoshiya Imamura, Leonardo Albarracín, Sudeb Saha, Yoshihito Suda, Shoichiro Kurata, María Ángela Jure, Haruki Kitazawa, et al. Hypermucoviscous Carbapenem-Resistant Klebsiella pneumoniae ST25 Infect Human Intestinal Epithelial Cells and Induce Moderate Inflammation. International Journal of Molecular Sciences. 2023. 24:8804. 1-16
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Stefania Dentice Maidana, Yoshiya Imamura, Mariano Elean, Leonardo Albarracín, Keita Nishiyama, Yoshihito Suda, Shoichiro Kurata, María Ángela Jure, Haruki Kitazawa, Julio Villena. Oral Administration of Lacticaseibacillus rhamnosus CRL1505 Modulates Lung Innate Immune Response against Klebsiella pneumoniae ST25. Microorganisms. 2023. 11:1148. 5. 1-13
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Fernanda Raya-Tonetti, Patricia Clua, Kohtaro Fukuyama, Guillermo Marcial, Jacinto Sacur, Gabriela Marranzino, Mikado Tomokiyo, Guadalupe Vizoso-Pinto, Apolinaria García, Shoichiro Kurata, et al. The Ability of Postimmunobiotics from L. rhamnosus CRL1505 to Protect against Respiratory Syncytial Virus and Pneumococcal Super-Infection Is a Strain-Dependent Characteristic. Microorganisms. 2022. 10:2185. 1-22
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Naoyuki Fuse, Chisaki Okamori, Ryoma Okaji, Chang Tang, Kikuko Hirai, Shoichiro Kurata. Transcriptome features of innate immune memory in Drosophila. PLOS Genetics. 2022. 18. 10. e1010005-e1010005
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MISC (11):
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H. Nagai, T. Yano, S. Kurata. Role of autophagy in Drosophila innate immunity. ISJ-INVERTEBRATE SURVIVAL JOURNAL. 2015. 12. 155-157
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後藤彰, 矢野環, 寺島潤, 倉田祥一朗. 新規抗菌ペプチドDrosophila Listericinの同定. 生化学. 2010. 82. 7. 667
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中島瑠美, 勝山朋紀, 寺島潤, 倉田祥一朗. 複眼を翅に改変する遺伝子winged eyeによるエピジェネティック制御. 生化学. 2007. 3P-0922
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S. Kurata, T. Katsuyama, T. Sugawara, M. Tatsumi, Y. Oshima, W. J. Gehring, T. Aigaki. Context-dependent involvement of winged eye encoding a chromatin-associated bromo-adjacent homology domain protein in Drosophila disc specification. MECHANISMS OF DEVELOPMENT. 2005. 122. S51-S51
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C Punzo, S Plaza, M Seimiya, P Schnupf, S Kurata, J Jaeger, WJ Gehring. Functional divergence between eyeless and twin of eyeless in Drosophila melanogaster (vol 131, pg 3943, 2004. DEVELOPMENT. 2004. 131. 18. 4635-4635
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Books (2):
-
The origin of life science researches
青山社 2003
-
細胞社会とその形成
東京大学出版会 1989
Education (2):
- - 1990 The University of Tokyo Graduate School, Division of Pharmaceutical Sciences 生命薬学
- - 1985 Yamagata University Faculty of Science 生物学科
Professional career (2):
- Ph D (The University of Tokyo)
- 理学修士 (Yamagata University)
Work history (4):
- 1998/03 - 現在 Graduate School of Pharmaceutical Sciences, Tohoku University
- 1995/04 - 1998/03 Postdoctoral research fellow, Swiss National Science Foundation
- 1991/04 - 1998/03 University of Tokyo, Assistant Professor
- 1990/04 - 1991/03 Postdoctoral research fellow, Fellowships of the Japan Society for the Promotion of Science for Japanese Junior Scientists.
Association Membership(s) (6):
日本発生生物学会
, 日本生体防御学会
, 日本比較免疫学会
, 日本薬学会
, 日本分子生物学会
, 日本生化学会
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