Takei Kohji

タケイコウジ | Takei Kohji

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www.okayama-u.ac.jp/user/med/biochem/hyoushi.html

Research field (1)： Cell biology

Research keywords (6)：細胞骨格 , 細胞内小胞輸送 , 細胞生物 , cytoskeleton , membrane traffic , cell biology

Research theme for competitive and other funds (10)：

2021 - 2024 Elucidation of morphogenesis, maintenance and stabilization, and maintenance mechanism of glomerular podocytes by microtubule bundles
2019 - 2022 Elucidation of the function of novel actin-binding factors in neutrophil phagocytosis and extracellular trap formation
2019 - 2022 Cooperative regulation of cytoskeleton and membrane dynamics by novel mechanism of dynamin
2016 - 2019 Development of the anti-invasive drug for treatment of malignant glioma by drug-repositioning of anti-depressant.
2015 - 2018 Molecular regulatory mechanism of podocyte, the filtration apparatus of glomeruli

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Papers (45)：

Hiromichi Okuma, Yumiko Saijo-Hamano, Hiroshi Yamada, Aalaa Alrahman Sherif, Emi Hashizaki, Naoki Sakai, Takaaki Kato, Tsuyoshi Imasaki, Satoshi Kikkawa, Eriko Nitta, et al. Structural basis of Irgb6 inactivation by Toxoplasma gondii through the phosphorylation of switch I. Genes to cells : devoted to molecular & cellular mechanisms. 2023
Tetsuya Takeda, Hiroshi Yamada, Kohji Takei. Dynamin: molecular scissors for membrane fission. Plasma Membrane Shaping. 2023. 77-90
Hiroshi Yamada, Tadashi Abe, Hikaru Nagaoka, Eizo Takashima, Ryo Nitta, Masahiro Yamamoto, Kohji Takei. Recruitment of Irgb6 to the membrane is a direct trigger for membrane deformation. Frontiers in Cellular and Infection Microbiology. 2022. 12
Haymar Wint, Jianzhen Li, Tadashi Abe, Hiroshi Yamada, Yasutomo Nasu, Masami Watanabe, Kohji Takei, Tetsuya Takeda. Pacsin 2-dependent N-cadherin internalization regulates the migration behaviour of malignant cancer cells. 2022
Tetsuya Hori, Kohgaku Eguchi, Han-Ying Wang, Tomohiro Miyasaka, Laurent Guillaud, Zacharie Taoufiq, Satyajit Mahapatra, Hiroshi Yamada, Kohji Takei, Tomoyuki Takahashi. Microtubule assembly by tau impairs endocytosis and neurotransmission via dynamin sequestration in Alzheimer's disease synapse model. eLife. 2022. 11

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MISC (90)：

竹田哲也, 藤瀬賢志郎, 山田浩司, 竹居孝二. 細胞操作と定量イメージングで知る細胞骨格ダイナミズム細胞の形態形成における膜-細胞骨格の動的相互作用. 日本細胞生物学会大会講演要旨集. 2020. 72回. W3-5
山田浩司, The Mon La, 竹田哲也, 阿部匡史, 淺沼克彦, 竹居孝二. 腎糸球体ポドサイトにおけるアンフィファイジン1の機能. 日本生化学会大会プログラム・講演要旨集. 2019. 92回. [3P-138]
阿部匡史, The Mon La, 橘洋美, 竹田哲也, 竹居孝二, 山田浩司. 腎糸球体ポドサイトにおけるダイナミンイソフォームの局在と機能. 日本生化学会大会プログラム・講演要旨集. 2019. 92回. [3P-139]
藤瀬賢志郎, 山田浩司, 竹居孝二, 竹田哲也. 筋細胞膜リモデリングにおけるメカニカルストレス応答の解析. 日本筋学会学術集会プログラム・抄録集. 2019. 5回. 107-107
竹居孝二, 山田浩司, 竹田哲也. A Novel Membrane Fission Mechanism by Dynamin Complex: Clusterase Model. 生物物理(Web). 2019. 59. 5

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Patents (1)：

Books (5)：

Use of liposomes to study vesicular transport
Humana Press 2010
Methods in Molecular Biology “Liposomes”
Humana Press (USA), Springer Publishing Group, 2009
生体の科学55
医学書院,東京 2004
文部科学省科学研究費特定領域研究C「ゲノム」2000年度報告書
2001
平成12?13年度科学研究費補助金(基盤研究(B)(2))研究成果報告書

Lectures and oral presentations (19)：

Elucidation of cytoskeletal dynamics in glomerular podocyte
(The 96th Annual Meeting of the Japanese Biochemical Society 2023)
Recruitment of Irgb6 to the Membrane Directly Triggers Membrane Deformation
(The 95th Annual Meeting of the Japanese Biochemical Society 2022)
Allosteric changes of hecto-scale population of dynamin GTPases provide in dynamic regulation of membranes and cytoskeletons
(The 60th Annual Meeting of the Biophysical Society of Japan 2022)
Dynamin-dependent microtubule regulation and morphogenesis of glomerular podocyte
(The 74th Annual Meeting of the Japanese Society for Cell Biology 2022)
ダイナミン2の自己重合と膜との相互作用は糸球体ポドサイトのアクチン制御に重要である
(第62回日本生化学会中国・四国支部例会 2021)

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Education (4)：

Professional career (1)：

Work history (11)：

2001 - 2005 岡山大学医歯学総合研究科未設定
2005 - - 岡山大学医歯薬学総合研究科教授
2005 - - Professor,Graduate School of Medicine, Dentistry and Pharmaceutical Sciences,Okayama University
1995 - 1999 ハワードヒューズ医学財団リサーチスペシャリスト
1995 - 1999 Research Specialist II,Howard Hughes Medical Institute

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Association Membership(s) (5)：

日本生物物理学会 , 日本神経科学学会 , 日本細胞生物学会 , The Biophysical Society of Japan , The Japan Neuroscience Society

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