TOSHIO OHHASHI

オオハシトシオ | TOSHIO OHHASHI

Affiliation and department：
Job title： Appointed Professor

Research field (4)： Gastroenterology , Biomedical engineering , Nutrition and health science , Physiology

Research theme for competitive and other funds (22)：

2018 - 2021 Development of the methods for evaluating the ability of absorption in human jejunum and for assessing the absorptive substance-mediated changes in gut immunity
2014 - 2017 Establishment of a system and method for evaluating physiological function of traditional Japanese foods
2012 - 2015 New concept of pulmonary blood flow-mediated CO2 gas excretion in the lungs
2012 - 2014 Development of imaging changes in microenvironment with in the sentinel lymph node combined with micrometastasis of carcinoma cells
2010 - 2014 Molecular and physiological approach for addressing the mechanisms of micrometastasis of carcinoma cells within the sentinel lymph node

2007 - 2009 A study of the establishment of the medical intellectual property management method and the talented person training

2007 - 2009 Basic and clinical research for evaluating micro-environmental changes in sentinel lymph node produced by micro-metastasis of carcinoma cell.

2005 - 2006 前哨リンパ節(SLN)への癌転移因子解明のリンパ学的研究

2005 - 2005 門脈学の総合的研究領域の策定

2003 - 2004 前哨リンパ節への癌転移因子解明のリンパ生理学的研究

1999 - 2000 Physiome and pathophysiome research projects for studying cooperative functions of interstitial space and lymphatic system.

1998 - 1999 Electorical properties of the endothelial cel1s in cultured lymphatic vessels from dog thoracic ducts

1997 - 1998 リンパ行性癌転移機構の解明を目指した細胞生理学的萌芽研究

1996 - 1997 Physiological roles of lymphatic endothelial cells on lymph formation and transport

1995 - 1996 DEVELOPMENT OF A NEW EXPERIMENTAL APPARATUS FOR STUDYING OF MECHANICAL ACTIVITY OF ISOLATED ARTERIOLES.

1994 - 1995 Cell physiological approach for evaulating effects of lymphatic endothelial cells on lymph formation and transport

1992 - 1994 Development of a new appratus for continuous recording of mechanical activity of isolated arterioles

1992 - 1993 ANALYSIS OF ENDOTHELIUM-DERIVED CONTRACTILE OR RELAXING FACTORS IN LYMPHATIC ENOTHELIAL CELLS

1989 - 1989 臓器微小循環と物質代謝及びその障害に関する分子生物学的・医工学的研究

1988 - 1989 Physiological roles in neutral and humoral control of venous system

1986 - 1987 Constuction of new devices to measure on outer and inner diameter and wall thickness with an image sensot, an ared image senseor of a X-ray image sensor applicable in small blood and lymph vessels

1986 - 1987 Functional and morphological characteristics of venous system with special references in cardiovascular regulation

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Papers (20)：

Nariaki Arai, Ryo Kajihara, Mieko Takasaka, Kei Amari, Norika Kuneshita, Daisuke Maejima, Tomomi Watanabe-Asaka, Moyuru Hayashi, Yumiko Yokoyama, Maki Kaidoh, et al. Cell surface ATP synthase-released H+ and ATP play key roles in cocoa butter intake-mediated regulation of gut immunity through releases of cytokines in rat. Pflugers Archiv : European journal of physiology. 2023. 475. 8. 945-960
Hideya Momose, Mieko Takasaka, Tomomi Watanabe-Asaka, Moyuru Hayashi, Daisuke Maejima, Yoshiko Kawai, Toshio Ohhashi. Heatstroke risk informing system using wearable perspiration ratemeter on users undergoing physical exercise. Scientific reports. 2023. 13. 1. 416-416
Toshio Ohhashi, Yoshiko Kawai, Daisuke Maejima, Moyuru Hayashi, Tomomi Watanabe-Asaka. Physiological Roles of Lymph Flow-Mediated Nitric Oxide in Lymphatic System. Lymphatic research and biology. 2022. 21. 3. 253-261
河合佳子, 林もゆる, 浅香智美, 前島大輔, 大橋俊夫. リンパ管疾患への挑戦(リンパ瘻、リンパ浮腫) リンパ管の機能解析リンパ瘻、リンパ浮腫の病態理解のために. 脈管学. 2022. 62. Suppl. S114-S114
Ide S, Arai N, Morimitsu N, Momose H, Hayashi M, Watanabe-Asaka T, Ishida T, Tanaka S, Seto T, Kawai Y, et al. Another route of CO2 gas excretion independent of red blood cells in human lungs. Pflügers Archiv - European Journal of Physiology ,https:// doi.org/10.1007/s00424-021-02586-3. 2021

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MISC (4)：

林もゆる, 林もゆる, 浅香智美, 浅香智美, 前島大輔, 河合佳子, 河合佳子, 大橋俊夫. Water intake mediated secretion of ATP from myofibroblast cells in rat jejunum regulates the IL-22-dependent innate immunity. リンパ学. 2021. 44. 1. 10-12
河合佳子, 林もゆる, 浅香智美, 大橋俊夫. 脈管としてのリンパ管の再考-リンパ学の基礎と臨床- 流れ刺激がリンパ管の機能におよぼす影響について. 脈管学. 2020. 60. Suppl. S95-S95
林もゆる, 浅香智美, 前島大輔, 河合佳子, 大橋俊夫. 尿の浸透圧変化からヒト胸管リンパ流量を推定する測定法の開発. 日本生理学雑誌. 2020. 82. 2. 25-25
林もゆる, 浅香智美, 前島大輔, 河合佳子, 大橋俊夫. 尿の浸透圧変化からヒト胸管リンパ流量を推定する測定法の開発. 日本生理学雑誌. 2020. 82. 2. 25-25

Works (3)：

日本リンパ学会理事長
2001 - 現在
日本発汗学会設立(理事長, 名誉理事長)
1993 - 現在
長野県ライフサイエンス研究会設立運営(専務理事)
1993 -

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