Rchr
J-GLOBAL ID：200901054677847671   Update date: Jan. 30, 2024

Takino Takahisa

タキノ タカヒサ | Takino Takahisa
Affiliation and department：
Kanazawa University Institute of Liberal Arts and Science

About Kanazawa University Institute of Liberal Arts and Science


Research field  (2)： Experimental pathology ,  Pathobiochemistry
Research keywords  (1)： 腫瘍細胞
Research theme for competitive and other funds  (20)：
  • 2021 - 2024 Cross-talk between cancer cells and fibroblasts during cancer progression.
  • 2020 - 2023 消化器癌におけるNa+/H+交換輸送体5の機能解析と特異的阻害薬の開発
  • 2016 - 2019 肝細胞がんの多様性・変幻性におけるMT1-MMP依存性分子経路の解析
  • 2011 - 2014 細胞外マトリックス分解と細胞運動の極性形成維持機構
  • 2010 - 2013 膜型マトリックスメタロプロテアー ゼ-1のがん悪性化形質に果たす役割の解析
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Papers (79)：
  • Gerelsuren Batbayar, Akihiko Ishimura, Hanbing Lyu, Sasithorn Wanna-Udom, Makiko Meguro-Horike, Minoru Terashima, Shin-Ichi Horike, Takahisa Takino, Takeshi Suzuki. ASH2L, a COMPASS core subunit, is involved in the cell invasion and migration of triple-negative breast cancer cells through the epigenetic control of histone H3 lysine 4 methylation. Biochemical and biophysical research communications. 2023. 669. 19-29
  • Kusuma Suphakhong, Minoru Terashima, Sasithorn Wanna-Udom, Risa Takatsuka, Akihiko Ishimura, Takahisa Takino, Takeshi Suzuki. m6A RNA methylation regulates the transcription factors JUN and JUNB in TGF-β-induced epithelial-mesenchymal transition of lung cancer cells. The Journal of biological chemistry. 2022. 298. 11. 102554-102554
  • Hirari Yamahana, Yuki Komiya, Takahisa Takino, Yoshio Endo, Hisatsugu Yamada, Chikako Asada, Yoshihiro Uto. Structure-Activity Relationships of UTX-121 Derivatives for the Development of Novel Matrix Metalloproteinase-2/9 Inhibitors. Chemical and Pharmaceutical Bulletin. 2021. 69. 10. 1017-1028
  • Hirari Yamahana, Minoru Terashima, Risa Takatsuka, Chikako Asada, Takeshi Suzuki, Yoshihiro Uto, Takahisa Takino. TGF-β1 facilitates MT1-MMP-mediated proMMP-9 activation and invasion in oral squamous cell carcinoma cells. Biochemistry and biophysics reports. 2021. 27. 101072-101072
  • Sasithorn Wanna-Udom, Minoru Terashima, Kusuma Suphakhong, Akihiko Ishimura, Takahisa Takino, Takeshi Suzuki. KDM2B is involved in the epigenetic regulation of TGF-β-induced epithelial-mesenchymal transition in lung and pancreatic cancer cell lines. Journal of Biological Chemistry. 2021. 296. 100213-100213
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MISC (19)：
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Patents (3)：
  • 生体組織から線維芽細胞を単離する方法及びそれに用いるキット
  • がん細胞浸潤能測定方法及び測定キット
  • 顕微鏡用細胞培養器
Books (4)：
  • 日本臨床増刊号 がん転移学(下)
    日本臨床社 2017
  • 実験医学増刊号 がんの微小環境と標的治療
    羊土社 2015
  • がん分子標的治療実践マニュアル
    金芳堂 2009
  • (続)がんの浸潤・転移研究マニュアル
    金芳堂 1997
Education (4)：
  • - 1995 Kanazawa University
  • - 1995 Kanazawa University Graduate School, Division of Medicine
  • - 1990 The University of Tokushima Faculty of Dentistry
  • - 1990 The University of Tokushima Faculty of Dentistry
Professional career (1)：
  • 医学博士 (金沢大学)
Work history (12)：
  • 2017/04 - 現在 Kanazawa University Institute of Liberal Arts and Science
  • 2016/04 - 2017/03 Kanazawa University Institute of Liberal Arts and Science
  • 2003/05 - 2016/03 Kanazawa University Cancer Research Institute
  • 1999/10 - 2003/04 Kanazawa University
  • 1999 - 2003 : Kanazawa University
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Committee career (5)：
  • 2018/04 - 現在 日本癌学会 評議員
  • 2007 - 現在 日本結合組織学会 評議員
  • 2005 - 現在 日本がん転移学会 評議員
  • 2007 - -: Japanese Society for Connective Tissue Research
  • 2005 - -: Japanese Association for Metastasis Research Society
Awards (3)：
  • 2005 - 第9回日本がん転移学会研究奨励賞
  • 2005 - 上原記念生命科学財団平成16年度研究奨励金
  • 2003 - 第17回北国がん基金研究助成
Association Membership(s) (11)：
歯科基礎医学会 ,  日本生化学会 ,  日本結合組織学会 ,  日本がん転移学会 ,  日本癌学会 ,  Japanese association for oral biology ,  Japanese Biochemical Society ,  American Society for Cell Biology ,  Japanese Society for Connective Tissue Research ,  Japanese Association for Metastasis Research Society ,  Japanese Cancer Association
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