Rchr
J-GLOBAL ID：200901054785415435
Update date: Apr. 09, 2024
Watanabe Tetsushi
ワタナベ テツシ | Watanabe Tetsushi
Affiliation and department：
Job title：
Associate Professor
Research field (3)：
Environmental dynamics
, Environmental impact assessment
, Pharmaceuticals - health and biochemistry
Research keywords (4)：
生物系薬学
, 環境系薬学
, Biological system pharmaceutical science
, Environmental pharmaceutical science
Research theme for competitive and other funds (14)：
- 2021 - 2024 大気粉塵の炎症反応誘発性と喘息発作の関係の解明
- 2020 - 2024 がん化学療法抵抗性改善機能に基づく天然由来新規医薬品シーズの開拓
- 2017 - 2020 Association of bioaerosol in outdoor air with asthma exacerbation
- 2014 - 2017 Long-range transport and biological activity of inflammatry/allergic material
- 2009 - 2011 Identification and risk assessment of novel mutagens isolated from diabetes model
- 2006 - 2007 Detection and risk assessment of carcinogenic compounds in ambient air and surface soil
- 2004 - 2005 Detection and genotoxicity of nitroarenes in ambient air and surface soil
- 2003 - 2004 Formation of chloronitropyrenes and dinitropyrenes in metallic oxides as scil components in the presence of indoor air wth 1-nilropyrene and sodium chloride under xenon lamp irradiation
- 2000 - 2001 Study on environmental pollution with mutagens in high mortality areas by lung cancer
- 環境汚染物質の分析法の開発
- 環境変異原の検出とリスク評価
- Detection and risk assessment of environmental mutagens
- Study on enzymes participating in the metabolic activation of environmental mutagens
- DNA mutation Spectrum Caused by environmental mutagen
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Papers (97)：
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Takahiro Kitagawa, Takahiro Matsumoto, Tomoe Ohta, Tatsusada Yoshida, Youhei Saito, Yuji Nakayama, Yuki Hadate, Eishi Ashihara, Tetsushi Watanabe. Linderapyrone analogue LPD-01 as a cancer treatment agent by targeting importin7. Journal of Natural Medicines. 2024
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Takahiro Matsumoto, Erika Ohnishi, Masaya Okayama, Tomoe Ohta, Tatsusada Yoshida, Shiori Ando, Raku Kutose, Takahiro Kitagawa, Tetsushi Watanabe. Chemical structures and cell-death-inducing activities of metabolites produced by Penicillium maximae. Tetrahedron Letters. 2024. 134. 154851-154851
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Masaya Okayama, Takahiro Matsumoto, Takahiro Kitagawa, Seikou Nakamura, Tomoe Ohta, Tatsusada Yoshida, Tetsushi Watanabe. Cytotoxic activities of alkaloid constituents from the climbing stems and rhizomes of Sinomenium acutum against cancer stem cells. Journal of Natural Medicines. 2023
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Takahiro Matsumoto, Masaya Okayama, Hayato Yoshikawa, Shifu Maeda, Takahiro Kitagawa, Tetsushi Watanabe. Chemical structures and cell death inducing activities of the metabolites of Aspergillus terreus. HETEROCYCLES. 2023
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Takahiro Matsumoto, Erika Ohnishi, Takahiro Kitagawa, Masaya Okayama, Youhei Saito, Hayato Yoshikawa, Tomoe Ohta, Tatsusada Yoshida, Yuji Nakayama, Tetsushi Watanabe. Azaphilones produced by Penicillium maximae with their cell death-inducing activity on Adriamycin-treated cancer cell. Genes and environment : the official journal of the Japanese Environmental Mutagen Society. 2023. 45. 1. 5-5
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MISC (181)：
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北川翔大, 松本崇宏, 渡辺徹志. The mechanism of a new Wnt/β-catenin signaling inhibitor. 日本薬学会年会要旨集(Web). 2023. 143rd
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北川 翔大, 松本 崇宏, 今堀 大輔, 渡辺 徹志. 新規Wnt/β-catenin経路阻害剤のがん幹細胞に与える影響および構造活性相関の検討. 日本薬学会年会要旨集. 2022. 142年会. 26T-am08S
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吉川 勇人, 松本 崇宏, 北川 翔大, 今堀 大輔, 岡山 真也, 渡辺 徹志. カノコソウ(Valeriana fauriei)含有セスキテルペンによるHsp105発現抑制作用を介したがん細胞死誘導. 日本薬学会年会要旨集. 2022. 142年会. 26PO1-20S
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大西 英里加, 松本 崇宏, 今堀 大輔, 渡辺 徹志. ナンテン(Nandina domestica)含有成分のP-糖タンパク質阻害を介したがん細胞死誘導作用. 日本薬学会年会要旨集. 2022. 142年会. 26PO10-11S
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北川翔大, 松本崇宏, 芦原英司, 渡辺徹志. 新規Wnt/β-catenin経路阻害剤linderapyroneおよびその誘導体のがん幹細胞増殖抑制作用. がん予防学術大会プログラム・抄録集. 2022. 2022
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Education (3)：
- - 1984 静岡薬科大学大学院 薬学研究科 衛生化学
- - 1982 Kyoto Pharmaceutical University Pharmaceutical Sciences Pharmaceutical Biology
- - 1982 Kyoto Pharmaceutical University Faculty of Pharmaceutical Science
Professional career (1)：
- Doctor of Pharmaceutical Science
Awards (1)：
Association Membership(s) (5)：
日本環境化学会
, 日本大気環境学会
, 日本癌学会
, 日本環境変異原学会
, 日本薬学会
