Rchr
J-GLOBAL ID：200901055837598254
Update date: Oct. 15, 2024
Nagahara Noriyuki
ナガハラ ノリユキ | Nagahara Noriyuki
Affiliation and department：
Research field (3)：
Pathobiochemistry
, Medical biochemistry
, Functional biochemistry
Research keywords (2)：
Pathological Biochemistry
, Public Health and Health Science
Research theme for competitive and other funds (19)：
- 2020 - 2024 Signal molecules of ASCL1, a lineage-specific transcription factor for small cell carcinoma of the lung
- 2020 - 2023 小児呼吸器腫瘍の網羅的遺伝子解析とプロテオーム解析を用いた創薬ターゲットの検索
- 2015 - 2019 Development of highly precise diagnostic markers for pediatric neoplasms
- 2015 - 2018 Hydrogen sulfide and sulfur oxdies production failure model: metabolic disorder in sulfurtransferase-knockout mice
- 2012 - 2015 Comprehensive study of sulfurtransferase-knockout mice associated with insufficiency of hydrogen sulfide production
- 2011 - 2013 The molecular basis of morphological atypism (proteome analysis of KRAS downstream factors)
- 2003 - 2005 Mechanism of organophosphorus pesticides-induced inhibition of immune function by using perforin knockout mice.
- 1997 - 2000 Structures and functions of metalloflavoenzymes which produce free radicals
- 1997 - 1997 小脳におけるパルス状一酸化窒素発生の分子機構
- 1995 - 1995 ラットグロビン遺伝子群におけるLCRと近位プロモーター領域との相互作用の解析
- 1994 - 1994 ラットグロビン遺伝子群における発生段階及び組織特異的な遺伝子発現の調節機構
- シアン中毒の発症及び防御メカニズム
- 硫黄転移酵素の反応機構
- 硫黄原子が関与する代謝調節
- 環境分子医学
- Sulfur -related mettablic regulation
- Defense mechanism against cyanicle toxication
- Reaction mechanism of sulfurtransferase
- Environmental molecular medicine
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Papers (77)：
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Keisuke Kato, Hiroaki Goto, Mio Tanaka, Tetsuomi Suzuki, Yasunori Toyoda, Masato Shinkai, Norihiko Kitagawa, Toshiji Nishi, Hisato Kigasawa, Kenji Kurosawa, et al. Establishment and Characterization of a Novel Pleuropulmonary Blastoma Cell Line. Genes, Chromosomes and Cancer. 2024. 63. 10
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Keisuke Kato, Jun-Ichi Nagai, Hiroaki Goto, Masato Shinkai, Norihiko Kitagawa, Yasunori Toyoda, Toshiji Nishi, Hisato Kigasawa, Mio Tanaka, Kenji Kurosawa, et al. Establishment and characterization of a novel MDM2/MYCN-co-amplified neuroblastoma cell line, NBN-SHIM, established from a late recurrent stage MS tumor. Human cell. 2024
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Nagahara N, Ito T. 3-Mercaptopyruvate sulfurtransferase: The molecular and functional properties. FOUNDATIONS AND FRONTIERS IN ENZYMOLOGY SERIES. 2023. 1-258
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Zhen Li, Huijing Xia, Thomas E. Sharp, Kyle B. LaPenna, John W. Elrod, Kevin M. Casin, Ken Liu, John W. Calvert, Vinh Q. Chau, Fadi N. Salloum, et al. Mitochondrial H 2 S Regulates BCAA Catabolism in Heart Failure. Circulation Research. 2022. 131. 3. 222-235
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Antonia Katsouda, Dimitrios Valakos, Vasilios S. Dionellis, Sofia-Iris Bibli, Ioannis Akoumianakis, Sevasti Karaliota, Karim Zuhra, Ingrid Fleming, Noriyuki Nagahara, Sophia Havaki, et al. MPST sulfurtransferase maintains mitochondrial protein import and cellular bioenergetics to attenuate obesity. Journal of Experimental Medicine. 2022. 219. 7
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MISC (53)：
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田中水緒, 梅本沙代子, 永原則之, 田中祐吉. 組織学的・細胞遺伝学的検討による先天性嚢胞性肺疾患の病因に基づく分類の試み. こども医療センター医学誌. 2019
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田中祐吉, 梅本沙代子, 永原則之, 田中水緒. 小児固形腫瘍における診断に有用な新規マーカーの開発と臨床応用. こども医療センター医学誌. 2019
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田中水緒, 吉田美沙, 永原則之, 田中祐吉. 組織学的・細胞遺伝学的検討による先天性嚢胞性肺疾患の病因に基づく分類の試み. こども医療センター医学誌. 2018
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田中祐吉, 田中水緒, 吉田美沙, 永原則之. 小児固形腫瘍における診断に有用な新規マーカーの開発と臨床応用. こども医療センター医学誌. 2018
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田中水緒, 吉田美沙, 永原則之, 田中祐吉. 組織学的・細胞遺伝学的検討による先天性嚢胞性肺疾患の病因に基づく分類の試み. こども医療センター医学誌. 2017
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Books (7)：
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Sulfurtransferases, Essential Enzymes for Life
Elsevier 2023
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Pharmacological usage of a selective inhibitor of 3-mercaptopyruvate sulfurtransferase to control H2S and polysulfide generation
Elsevier 2018
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Updated report on a novel mercaptopyruvate sulfurtransferase thioredoxin-dependent redox-sensing molecular switch: A mechanism for the maintenance of cellular redox equilibrium
Bentham Science Publishers 2012
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Redox-sensing cysteine dependent-molecular switches, Intramolecular disulfide formation
Nova Science Publishers, Inc. 2012
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Cancer stem cells in lung cancer: distinct differences between small cell lung carcinoma and non-small cell lung carcinoma
2011
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Lectures and oral presentations (119)：
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3-Mercaptopyruvate Sulfurtransferase is a Critical Regulator of Branched-Chain Amino Acid Catabolism in Cardiometabolic HFpE
(Basic Cardiovascular Sciences 2024, American Heart Association 2024)
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3-メルカプトピルビン酸イオウ転移酵素の活性調節と生理機能(古くて新しいイオウとセレンの生化学:その多様な生理機能)
(第93回日本生化学会大会 2020)
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Genetic knockout of 3-mercaptopyruvate sulfurtransferase increases acute myocardial ischemia/reperfusion injury in aged mice
(Experimental Biology 2020)
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Complementary roles for 3-mercaptopyruvate sulfurtransferase and cystathionine γ-lyase in angiogenesis
(American Heart Association Scientific Sessions 2019)
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Overexpression of rhodanese in 3-mercaptopyruvate sulfurtransferase-knockout mice
(第92回日本生化学会総会 2019)
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Education (2)：
- - 現在 Nippon Medical School
- - 1998 Nippon Medical School
Professional career (1)：
Work history (2)：
- Nippon Medical School
- Nippon Medical School Faculty of Medicine, Department of Medicine Associate Professor
Association Membership(s) (2)：
生化学会
, American Society for Biochemistry and Molecular Biology
