Research keywords (3)：
oral cancer
, intercellular transport
, osteoclast
Research theme for competitive and other funds (47)：
2024 - 2027 膜ダイナミクスをターゲットとしたがん骨転移ニッチモデルと病態制御機構の開発
2023 - 2026 Roles of cancer extracellular vesicles in hijacking macrophages and metastatic niche formation
2023 - 2026 Roles of cancer extracellular vesicles in hijacking macrophages and metastatic niche formation
2020 - 2023 三次元腫瘍オルガノイド評価系により見出された新規癌転移抑制化合物の創薬展開
2017 - 2021 Drug repositioning using the gene promoter activity-based anticancer drug screening system
2017 - 2021 MZF1-Driven Cancer Stem-Like Resistance Against Cell Stress
2017 - 2020 Discovery of a novel gene regulating membrane trafficking of immune cells and elucidation of its pathology
2016 - 2019 Elucidation of Keap1/Nrf2-mediated control system of bone metabolism and application to in silico drug discovery
2016 - 2019 Molecular mechanism of bone destruction in rheumatoid arthritis based on CD147
2016 - 2019 フラボノイドをベースにした抗がん作用をもつサプリメントの開発
2016 - 2018 Analyses using bioimaging of invasion and colonization mechanisms by periodontal bacteria in the liver
2016 - 2018 破骨細胞におけるリソソーム分泌機構の制御因子の同定と分子メカニズムの解析
2015 - 2018 Examination of new medicine for bone metabolism by investigation of potential natural drugs in China
2014 - 2016 Development of detection systems for polyphenols that inhibit osteoclast formation and its applications
2013 - 2016 Analysis of new functions of an intracellular protease in epithelial cancers
2013 - 2016 Elucidation of molecular mechanisms of Nrf2-mediated osteoclastogenesis and search of natural products as molecular targets
2013 - 2016 Elucidation of the mechanism of systemic diseases by a periodontal pathogen in the intracellular transport
2012 - 2015 Phylogenetic and biochemical approach for identifying the chronic proinflammatory proteins accumulated in protease-deficient species and individuals
2012 - 2015 ステロイドによって誘発される膜タンパク質の細胞生物学的解析
2012 - 2014 Mechanistic analysis of periodontal bacteria attached on cardiovascular tissues by live-imaging
2011 - 2012 破骨細胞に関するカテプシンEの役割と創薬にむけた探求
2010 - 2012 Pathological analysis of epithelial cells in periodontitis
2010 - 2012 Elucidation of molecular mechanisms of osteoclastogenesis by iron
2009 - 2011 骨疾患における創薬のターゲットとなりうるプロテアーゼの作用機序の解明
2009 - 2011 The role of cathepsin E in osteoclast and the research for substrate molecule binding with cathepsin E
2007 - 2011 Elucidation of autophagy in development of periodontitis and its application of therapy
2008 - 2010 Role(s) of pepstatin A-sensitive aspartic proteinases in osteoclast differentiation
2007 - 2009 歯周病原性細菌の産生するプロテアーゼの膜輸送システムの解明
2007 - 2008 Basic studies for drug discovery using adhesin domain protein and interdomain regional peptide of Porphyromonas gingivalis
2005 - 2007 歯周病原性細菌におけるタンパク質発現機構の確立
2004 - 2005 歯周病に関わる因子における細胞生物学的研究
2003 - 2005 歯周病原性細菌の産生するプロテアーゼの高次構造と輸送機構に関する研究
2004 - 2005 歯周病原性細菌におけるタンパク質の新規膜透過システムの解明
2004 - 2005 FUNCTIONAL REGULATION OF OSTEOCLAST BY GLYCOSPHINGOLIPID
2003 - 2005 Study of the correlation bone in osteoclast resorption with atopic disease
2001 - 2004 ESTABLISHMENT OF A CLINICAL TREATMENT SYSTEM FOR PERIODONTAL DISEASE
江口傑徳, 江口傑徳, 十川千春, 岡元邦彰. Application of Organoids and Extracellular Vesicles to Cancer Research. Journal of Oral Biosciences Supplement (Web). 2020. 2020
