1999 - 2001 Application of plasma proteins as blood substitutes
1999 - 2000 Design and Evaluation of Albumin Mutants for Clinical Application
1998 - 2000 Design and Functional Evaluation of Albumin Mutants for Improving Medicinal Efficacy
1997 - 1999 Topology Analysis of Drug Binding Sites on Serum Proteins using Photoaffinity Labeling Techniques
1997 - 1998 病態時における薬物の血清蛋白結合の分子機能学的動態解析
1995 - 1997 Development of Pharmaceutical Additives-Evaluation of Protein and Polysaccharide Hydrolysates as Carrier to Enhance Absorption Rate of Drug
1994 - 1995 Microenviromental Analysis of Drug Binding Site on Albumin by Point-mutation and Using Probe
1990 - 1991 Microenvironmental Analysis of Drug Binding Sites on Human Serum Albumin and alpha_1-Acid Glycoprotein
化学修飾化による薬物の生体内挙動の改善と生体反応の修飾
天然高分子を利用した薬物の製剤設計
薬物の血清蛋白結合に関する研究
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Papers (819)：
Mayumi Ikeda-Imafuku, Tatsuya Fukuta, Victor Tuan Giam Chuang, Tomohiro Sawa, Toru Maruyama, Masaki Otagiri, Tatsuhiro Ishida, Yu Ishima. Acute Kidney Injury Caused by Rhabdomyolysis Is Ameliorated by Serum Albumin-Based Supersulfide Donors through Antioxidative Pathways. Pharmaceuticals (Basel, Switzerland). 2024. 17. 1
Kindness L Commey, Airi Enaka, Ryota Nakamura, Asami Yamamoto, Kenji Tsukigawa, Koji Nishi, Daisuke Iohara, Fumitoshi Hirayama, Masaki Otagiri, Keishi Yamasaki. Development of α-Cyclodextrin-Based Orally Disintegrating Tablets for 4-Phenylbutyrate. Pharmaceutics. 2024. 16. 1
Keishi Yamasaki, Masahiro Tokuno, Kenji Tsukigawa, Yuka Nagatsuka, Koji Nishi, Masaki Otagiri, Yuhki Sato. Possible Involvement of Protein Binding Inhibition in Changes in Dexmedetomidine Concentration in Extracorporeal Circuits during Midazolam Use. Biological & pharmaceutical bulletin. 2024. 47. 2. 389-393
Takashi Hasegawa, Kenji Tsukigawa, Kindness Commey, Mina Sakuragi, Shuhei Imoto, Kazuaki Taguchi, Koji Nishi, Masaki Otagiri, Keishi Yamasaki. Preparation and in Vitro Characterization of Fatty-Acid Modified Pirarubicin Nanosuspensions Stabilized by Albumin. Chemical & pharmaceutical bulletin. 2024. 72. 1. 21-27
Ishima Yu, Maruyama Toru, Otagiri Masaki, Chuang Victor T G, Ishida Tatsuhiro. The new delivery strategy of albumin carrier utilizing the interaction with albumin receptors. Chemical & Pharmaceutical Bulletin. 2022. Vol.70. No.5. 330-333
Akito Kawai, Keishi Yamasaki, Masaki Otagiri. Structure study of human serum albumin complexed with aripiprazole. Photon Factory Activity Report 2018. 2019. #36
Taguchi K, Maruyama T, Otagiri M. Use of hemoglobin for delivering exogenous carbon monoxide in medicinal applications. 2019
