Rchr
J-GLOBAL ID:200901056063849808
Update date: Mar. 22, 2024
Kanai Yoshiakira
カナイ ヨシアキラ | Kanai Yoshiakira
Affiliation and department:
Homepage URL (1):
http://www.vm.a.u-tokyo.ac.jp/kaibo/Sox17.html#sox17_101
Research field (1):
Veterinary medicine
Research keywords (7):
精原幹細胞ニッチ
, 胆嚢
, endoderm formation
, SOX17
, SRY
, Sertoli valve
, sex differentiation
Research theme for competitive and other funds (21):
- 2022 - 2025 Analysis of the mechanism of maintaining sexually robustness in mammalian fetal testis development
- 2020 - 2023 胆嚢のマスター遺伝子SOX17の発現制御と胆汁うっ滞性疾患
- 2019 - 2023 Gene expression analysis and subtype classification in the somatic cells of the mammalian ovary.
- 2019 - 2020 精子形成の品質保証とluminal flowによる精上皮クリアランス機構
- 2012 - 2017 Morphogenesis, regeneration and congenital disease in gallbladder and bile duct system in mammals
- 2009 - 2010 マウス支持細胞のニッチ形成能の性的可塑性
- 2008 - 2010 哺乳動物の精子の性差の分子基盤の解明
- 2008 - 2010 Analysis of the toxicological effects of phthalate esters on testes by administration, culture and transplantation methods
- 2007 - 2008 Crucial roles of SOX17 in fetal liver development
- 2004 - 2008 A spatiotemporal SRY action in mammalian gonadal sex determination
- 2005 - 2006 雄性生殖幹細胞移植法及び精細管移植法を用いた生殖毒性試験法の確立
- 2005 - 2006 Redundant roles of Sox17 and Sox18 on cardiovascular development in mice
- 2003 - 2004 Redundant function of Sox17 and Sox18 in mouse angiogenesis
- 2002 - 2003 Morphological and molecular analyses on testiculture tissuer at hibernation period
- 2001 - 2002 A cell-autonomous activity of mouse Sox17 gene in mouse embryogenesis
- 2001 - 2002 Establishment of testis in vitro assay system for risk assessment of endocrine disrupters
- 1999 - 2000 Risk evaluation on endocrine disruptors using some testicular tissue culture systems
- 1999 - 2000 Functional analysis of mouse Sox17 gene by using the gene targeting method.
- 1999 - 2000 Analysis of mechanism of changes in function and size of golden hamster testis with special reference to TGF-β signal transduction
- 1995 - 1995 マウス生殖細胞の分化過程に伴うSox17遺伝子の機能調節機構の解析
- 1994 - 1994 マウス生殖細胞に発現するSry(精巣決定遺伝子)関連遺伝子の単離とその解析
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Papers (123):
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Watcharapon Promsut, Ryuichi Yamada, Shohei Takami, Nanae Miyazaki, Mami Uemura, Ryuji Hiramatsu, Naoki Takahashi, Yoshiakira Kanai. External genitalia phenotypes of a Mab21l1-null mouse model for cerebellar, ocular, craniofacial, and genital (COFG) syndrome. The Anatomical Record. 2023
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Kenya Imaimatsu, Ryuji Hiramatsu, Ayako Tomita, Hirotsugu Itabashi, Yoshiakira Kanai. Partial male-to-female reprogramming of mouse fetal testis by Sertoli cell ablation. Development (Cambridge, England). 2023. 150. 14
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Hiroshi Yomogita, Hikaru Ito, Kento Hashimoto, Akihiko Kudo, Toshiaki Fukushima, Tsutomu Endo, Yoshikazu Hirate, Yoshihiro Akimoto, Masayuki Komada, Yoshiakira Kanai, et al. A possible function of Nik-related kinase in the labyrinth layer of delayed delivery mouse placentas. The Journal of reproduction and development. 2022. 69. 1. 32-40
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Aya Uchida, Kenya Imaimatsu, Honoka Suzuki, Xiao Han, Hiroki Ushioda, Mami Uemura, Kasane Imura-Kishi, Ryuji Hiramatsu, Hinako M. Takase, Yoshikazu Hirate, et al. SOX17-positive rete testis epithelium is required for Sertoli valve formation and normal spermiogenesis in the male mouse. Nature Communications. 2022. 13. 7860. 7860-7860
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Kenya Imaimatsu, Aya Uchida, Ryuji Hiramatsu, Yoshiakira Kanai. Gonadal Sex Differentiation and Ovarian Organogenesis along the Cortical-Medullary Axis in Mammals. International Journal of Molecular Sciences. 2022. 23. 21. 13373-13373
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MISC (25):
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柳井翔吾, 馬場崇, 馬場崇, 井上実紀, 井上実紀, 高橋史也, 寺尾美穂, 高田修治, 石渡啓介, 中林一彦, et al. UTY, the histone demethylase encoded by the Y chromosome, regulates expression of immediate early genes in testicular Leydig cells without its histone demethylation activity. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
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UCHIDA Aya, SUZUKI Honoka, TAKASE Hinako M, HIRATE Yoshikazu, HIRAMATSU Ryuji, KUDO Akihiko, AKIMOTO Yoshihiro, KANAI Masami, KANAI Yoshiakira. Mouse rete testis regulates the formation of Sertoli valve epithelia and subsequent spermatogenesis. The Journal of Reproduction and Development Supplement. 2021. 114. OR-40-OR-40
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平手良和, 早川佳那, 中野有紀, 熊澤栞, 三浦健人, 金井克晃, 金井正美. SOX17による着床初期の陰窩形成とSOX9およびAmphiregulinの発現制御. 日本実験動物学会総会講演要旨集(Web). 2021. 68th
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柳井翔吾, 馬場崇, 馬場崇, 戌亥海, 宮林香奈子, HAN Soyun, 井上実紀, 高橋史也, 金井克晃, 大川恭行, et al. 性染色体構成の差異がライディッヒ細胞の遺伝子発現と機能に及ぼす影響. 日本分子生物学会年会プログラム・要旨集(Web). 2020. 43rd
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柳井翔吾, 馬場崇, 馬場崇, 戌亥海, 宮林香奈子, HAN Soyun, 井上実紀, 高橋史也, 金井克晃, 大川恭行, et al. XX/Sryオスマウスのライディッヒ細胞における遺伝子発現と精巣内ステロイドホルモン量の網羅的解析. 日本内分泌学会雑誌. 2020. 96. 4 (Web)
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Books (33):
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遺伝学の百科事典 : 継承と多様性の源 = Encyclopedia of genetics : origin of inheritance and diversity
丸善出版 2022 ISBN:9784621306604
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獣医組織学[第八版]
学窓社 2020 ISBN:9784873627731
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繁殖生物学(改訂版)
Interzoo 2020
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獣医発生学 第2版
学窓社 2019 ISBN:9784873627632
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獣医解剖・組織・発生学 [第二版]
学窓社 2019 ISBN:9784873627656
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Committee career (9):
- 2023/10 - 現在 日本獣医学会 理事
- 2021/07 - 現在 Biology of Reproduction誌 Board of Reviewing Editors
- 2014 - 現在 Sexual Development誌 Editorial Board Member
- 2012 - 現在 日本獣医解剖学会 理事
- 2010 - 現在 日本獣医学会 評議員
- 2005 - 現在 日本繁殖生物学会誌 Journal of Reproduction and Development 編集委員
- 2012 - 2016 日本農学会 運営委員
- 2011 - 2014 米国解剖学会誌 Developmental Dynamics Editorial Board Member
- 2011 - 2014 日本獣医学会誌 Journal of Veterinary Medical Scinece 編集委員
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