Rchr
J-GLOBAL ID:200901056085323729
Update date: Mar. 16, 2024
Nunomura Satoshi
ヌノムラ サトシ | Nunomura Satoshi
Affiliation and department:
Job title:
准教授
Homepage URL (1):
http://www.biomol.med.saga-u.ac.jp/medbiochem/index.php
Research field (5):
Laboratory animal science
, Dermatology
, Allergies and connective tissue disease
, Immunology
, Cell biology
Research keywords (7):
Immunology
, Fibroblast heterogneity
, IgE
, Mast cells
, Allergic disorder
, Periostin
, Extracellular matrix
Research theme for competitive and other funds (17):
- 2023 - 2026 ペリオスチン/αVβ3インテグリン経路を標的としたアトピー性皮膚炎の新規治療薬の開発
- 2022 - 2025 FADSマウスを用いたアトピー性皮膚炎の病態形成機構の解明と新たな治療戦略の構築
- 2021 - 2024 Clarification of the mechanism of the treatment-resistance of allergic diseases and establishment of the strategy of the treatment for it
- 2019 - 2022 アトピー性皮膚炎におけるPathogenic線維芽細胞の同定とその機能解析
- 2016 - 2019 Clarification of the mechanism of the chronicity of allergic diseases and establishment of the thrapeutic strategy against it
- 2016 - 2019 Elucidation of regulatory mechanism of mast cell activation by periostin
- 2015 - 2018 Development of a periostin detection kit of next generation
- 2013 - 2017 Regulation of mast cell activation by competitive inhibition of FceRI assembly
- 2013 - 2016 Clarification of the mechanism of the chronicity of allergic diseases and establishment of the thrapeutic strategy against it
- 2013 - 2016 Crosstalk between C/EBPalpha and GABP in myeloid differentiation and gene expression
- 2013 - 2016 Molecular analysis of mast cell activation in mouse models for autoinflammatory syndromes and its use for anti-inflammatory drug development
- 2013 - 2014 自己炎症性症候群マウスモデルにおけるマスト細胞活性化機構の解明
- 2010 - 2012 Elucidation and regulation of mast cell activation by FcεRIβ chain
- 2010 - 2011 Regulation of allergic inflammation by liver X receptor
- 2008 - 2009 マスト細胞活性化における糖代謝調節機構の解析
- 2008 - 2009 Role of mast cell activation in the development of rheumatoid arthritis
- 2007 - 2008 オキシステロールによるマスト細胞アポトーシス誘導機構の解析
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Papers (87):
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Isao Suzaki, Yuki Maruyama, Sawa Kamimura, Kojiro Hirano, Satoshi Nunomura, Kenji Izuhara, Hitome Kobayashi. Residual nasal polyp tissue following dupilumab therapy is associated with periostin-associated fibrosis. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 2024. 281. 4. 1807-1817
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Tadatsugu Morimoto, Takaomi Kobayashi, Hayato Ito, Masatsugu Tsukamoto, Tomohito Yoshihara, Hirohito Hirata, Koji Otani, Kenji Izuhara, Satoshi Nunomura, Masaaki Mawatari. Serum periostin levels correlate with severity of intervertebral disc degeneration. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2024
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Takeshi Nakahara, Daisuke Onozuka, Satoshi Nunomura, Hidehisa Saeki, Motoi Takenaka, Mai Matsumoto, Yoko Kataoka, Rai Fujimoto, Sakae Kaneko, Eishin Morita, et al. The ability of biomarkers to assess the severity of atopic dermatitis. The journal of allergy and clinical immunology. Global. 2024. 3. 1. 100175-100175
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Makiko Kido-Nakahara, Daisuke Onozuka, Kenji Izuhara, Hidehisa Saeki, Satoshi Nunomura, Motoi Takenaka, Mai Matsumoto, Yoko Kataoka, Rai Fujimoto, Sakae Kaneko, et al. Exploring patient background and biomarkers associated with the development of dupilumab-associated conjunctivitis and blepharitis. Allergology international : official journal of the Japanese Society of Allergology. 2023
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Satoshi Nunomura, Ryoji Ito, Yasuhiro Nanri, Yusuke Ohno, Yuko Honda, Hironobu Takedomi, Kenji Izuhara. Novel mechanisms by which benralizumab suppresses IgE expression in human B cells in humanized mice. Allergy. 2023. 78. 12. 3271-3273
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MISC (32):
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Satoshi Nunomura, Kazunari Sugita, Kazuhiko Arima. Legends of allergy and immunology: Kenji Izuhara. Allergy. 2024
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Satoshi Nunomura. [STUDY OF ALLERGIC DISORDERS USING MOUSE MODEL]. Arerugi = [Allergy]. 2024. 73. 1. 1-5
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布村 聡, 北島 勲, 出原 賢治. アレルギー用語解説シリーズ FADSマウス. アレルギー. 2022. 71. 9. 1145-1146
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布村 聡. FADSマウス アトピー性皮膚炎およびアトピー性角結膜炎の新たなマウスモデル. 医学のあゆみ. 2022. 282. 3. 223-224
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岡山 吉道, 豊島 翔太, 伊崎 聡志, 遠藤 嵩大, 柏倉 淳一, 布村 聡, 中村 亮介, 秋山 晴代, 鐘ヶ江 加寿子, 高橋 恭子, et al. 自己免疫・アレルギー疾患の難治化におけるマスト細胞の役割の解明. 日本大学医学部総合医学研究所紀要. 2019. 7. 1-4
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Books (4):
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Advances in Asthma
Springer Singapore 2019 ISBN:9789811327902
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Evolution of Atopic Dermatitis in the 21st Century
Springer Singapore 2018 ISBN:9811055408
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病態と治療戦略がみえる 免疫・アレルギー疾患イラストレイテッド
羊土社 2013 ISBN:9784758120449
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免疫の事典
朝倉書店 2011 ISBN:4254310935
Lectures and oral presentations (187):
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FADSマウスを用いたアトピー性皮膚炎に対するデルゴシチニブの作用機序解析
(日本皮膚免疫アレルギー学会総会学術大会プログラム・抄録集 2023)
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眼アレルギー研究と臨床の進歩 重症アレルギー性結膜炎におけるタクロリムス点眼薬の治療応答性予測法の探索
(アレルギー 2023)
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ペリオスチンは実験的肺高血圧症の発症に関与する M2マクロファージの役割(Periostin is involved to the pathogenesis of experimental pulmonary hypertension: A role for M2 macrophage)
(日本呼吸器学会誌 2023)
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Electrophysiological and behavioral analysis of a novel mouse model of atopic dermatitis
(日本薬学会年会要旨集(Web) 2023)
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アレルギー性疾患の分子的および細胞多様性 アレルギー性皮膚炎における2型炎症とそう痒を伴うNF-κBを介した炎症におけるペリオスチンの新たな役割(Molecular and cellular diversity of allergic disease The emerging role of periostin in NF-κB-mediated inflammation with type 2 inflammation and itching in allergic skin inflammation)
(日本免疫学会総会・学術集会記録 2022)
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Education (1):
- - 2001 Tokai University Graduate School, Division of Medicine
Professional career (1):
Work history (5):
- 2017/07 - 現在 Saga University Faculty of Medicine
- 2015/12 - 2017/06 Saga University Faculty of Medicine
- 2007/04 - 2015/11 Nihon University School of Medicine
- 2006/04 - 2007/03 Nihon University School of Medicine
- 2001/06 - 2006/03 Nihon University School of Medicine
Committee career (3):
- 2019/06 - 現在 日本アレルギー学会 代議員
- 2020/10 - 2021/09 日本学術振興会 令和3年度科学研究費助成事業審査委員
- 2013/03 - 2014/12 日本アレルギー学会 第1回総合アレルギー講習会準備室ワーキンググループ委員
Awards (1):
- 2022/02 - 日本アレルギー学会 2022 年度「サノフィ優秀論文賞」
Association Membership(s) (6):
THE JAPANESE BIOCHEMICAL SOCIETY
, アレルギー・好酸球研究会
, 日本アレルギー協会
, 日本アレルギー学会
, 日本免疫学会
, 日本呼吸器学会
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