J-GLOBAL ID:200901056331053795   Update date: Apr. 05, 2019

Eguchi, Takanori

エグチ タカノリ | Eguchi, Takanori
Affiliation and department:
Homepage URL  (1): http://soran.cc.okayama-u.ac.jp/view?l=ja&u=4a131ed79cd93d5174506e4da22f6611&a2=1000007&o=affiliation&sm=affiliation&sl=ja&sp=5
Research keywords  (6): Cell differentiation ,  Stem cell ,  Bone and mineral metabolism ,  Biotechnology ,  Epigenetics ,  Gene Regulation
Research theme for competitive and other funds  (5):
  • 2015 - 2015 Role for intracellular MMP3 in cancer
  • 2010 - Research and Development of Periodontal Bone-Regenerative Method and Agent
  • 2009 - Fuseki for Longevity Society: Development of Bone Regenerative Medicine Targetting Holizontal Loss of the Periodontal Bone
  • 2008 - 2010 Evaluation of Physiological and Pathological Properties of MMP via Molecular Interactions
  • 2003 - 2006 Identification and characterization of cartilage-specific transcription factor
Papers (38):
  • Sogawa C, Eguchi T (Co-first author, Corresponding author), Okusha Y, Ono K, Ohyama K, Iizuka M, Kawasaki R, Hamada Y, Takigawa M, Sogawa N, Okamoto K, and Kozaki K. A reporter system evaluates tumorigenesis, metastasis, β-catenin/MMP regulation, and druggability. Tissue Engineering Part A. 2019
  • Toshifumi Fujiwara, Takanori Eguchi*, Chiharu Sogawa, Kisho Ono, Jun Murakami, Soichiro Ibaragi, Jun-ichi Asaumi, Stuart K Calderwood, Kuniaki Okamoto, Ken-ichi Kozaki. Carcinogenic epithelial-mesenchymal transition initiated by oral cancer exosomes is inhibited by anti-EGFR antibody cetuximab. Oral Oncology. 2018. 86. 251-257
  • Shimizu R, Ibaragi S, Eguchi T, Kuwajima D, Kodama S, Nishioka T, Okui T, Obata K, Takabatake K, Kawai H, Ono K, Okamoto K, Nagatsuka H, Sasaki A. Nicotine promotes lymph node metastasis and cetuximab resistance in head and neck squamous cell carcinoma. International journal of oncology. 2019. 54. 1. 283-294
  • Yuri Namba, Chiharu Sogawa, Yuka Okusha, Kisho Ono, Jun Murakami, Eriko Aoyama, Kazumi Ohyama, Jun-ichi Asaumi, Masaharu Takigawa, Kuniaki Okamoto, Stuart Keith Calderwood, Ken-ichi Kozaki, Takanori Eguchi*. Depletion of lipid efflux pump ABCG1 triggers the intracellular accumulation of extracellular vesicles and reduces aggregation and tumorigenesis of metastatic cancer cells. Frontiers in Oncology. 2018. 8. 376. 1-16
  • Fujiwara T, Eguchi T*, Sogawa C, Ono K, Murakami J, Ibaragi S, Asaumi JI, Okamoto K, Calderwood SK, Kozaki KI. Anti-EGFR antibody cetuximab is secreted by oral squamous cell carcinoma and alters EGF-driven mesenchymal transition. Biochemical and biophysical research communications. 2018. 503. 3. 1267-1272
Books (6):
  • エンドトキシン研究12:58-60. ヒストンアセチル化制御薬を用いたHMGB1の放出制御
    医学図書出版 2009
  • CCN Proteins in Health and Disease: Nucleophosmin/B23: A Multifunctional Regulator that Determines the Fate of CCN2 mRNA.
  • CCN proteins in Health and Diseases: Novel Transcriptional Regulation of CCN2/CTGF by Nuclear Translocation of MMP3
    Springer 2010
  • Promoter analyses of CCN genes. in Methods in Molecular Biology. CCN Proteins: Methods and Protocols
  • Regulatory Roles for Hsp70 in Cancer Incidence and Tumor Progression. In: Mario D. Galigniana (ed) Frontiers in Structural Biology, vol 1. Role of Molecular Chaperones in Structural Folding, Biological Functions, and Drug Interactions of Client Proteins.
Lectures and oral presentations  (28):
  • Novel transcriptional Regulation of CCN2/CTGF by Nuclear Translocation of MMP3 (シュプリンガー スカラシップ 受賞講演)
    (第5回国際CCN研究会 2008)
  • 日本軟骨代謝学会賞受賞講演
  • 岡山歯学会賞受賞講演
  • Control of Cdc37/Hsp90 and kinase signaling in prostate cancer by SCAN domain proteins.
    (国際ハイパーサーミア腫瘍学会第11回大会・日本ハイパーサーミア学会第29回大会合同大会 2012)
  • 間葉系幹細胞の骨細胞分化における新規の マイクロRNAバイオマーカー(講演)
    (Molecular Biology of Calcified Tissueセミナー 2013)
Work history (4):
  • 2009/01 - 2011/06 NCGG Section Chief
  • 2011/07 - 2011/08 BIDMC, Harvard Medical School Research fellow
  • 2011/09 - 2015/12 Harvard Medical School Instructor
  • 2016/04 - 現在 Okayama Univ, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences Assistant Professor
Awards (4):
  • 2018/09 - Okayama University Best Presentation Award
  • 2009 - Award, Japanese Society of Cartilage Metabolism
  • 2009 - Encouragement Award, Okayama Dental Society
  • 2008 - Springer Scholarship, 5th Workshop for International CCN Society
Association Membership(s) (11):
THE JAPANESE PHARMACOLOGICAL SOCIETY ,  BioMedical Society of Stress Response (BSSR) ,  THE JAPANESE CANCER ASSOCIATION ,  Japanese Association for Oral Biology ,  Japanese Society of Periodontology ,  Japanese Biochemical Society ,  Japan CCN Society ,  International CCN Society ,  Japan Society for Cartilage Metabolism ,  American Society for Bone and Mineral Research ,  Molecular Biology Society of Japan
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