Rchr
J-GLOBAL ID：200901056708363441   Update date: Jan. 30, 2024

Yugawa Takashi

ユガワ タカシ | Yugawa Takashi
Affiliation and department：
National Cancer Center Center for Cancer Genomics and Advanced Therapeutics (C-CAT)

About National Cancer Center Center for Cancer Genomics and Advanced Therapeutics (C-CAT)


Job title： Senior Staff Scientist
Homepage URL  (1)： http://www.nccri.ncc.go.jp/jimu/030/080/20151209151231.html
Research field  (4)： Virology ,  Pathobiochemistry ,  Cell biology ,  Molecular biology
Research keywords  (7)： Rock ,  Notch ,  p63 ,  p53 ,  cellular differentiation ,  carcinogenesis ,  Human papillomavirus
Research theme for competitive and other funds  (5)：
  • 2014 - 2018 NOTCH1の扁平上皮がんにおける二面性の分子基盤
  • 2011 - 2013 新規p63-MYC経路の異常を介した上皮がん悪性転換機構の解明
  • 2008 - 2010 ヒト正常上皮細胞におけるp53-Notch1経路の破綻とがん化
  • 2006 - 2007 子宮頚がん発生におけるHPV DNAの組み込みとE6、E7発現増加機構の解明
  • 2002 - 2004 Analyzing mechanism of oncogenesis by human papillomavirus
Papers (20)：
  • Wongjampa W, Nakahara T, Tanaka K, Yugawa T, Ekalaksananan T, Kleebkaow P, Goshima N, Kiyono T, Pientong C. An in vitro carcinogenesis model for cervical cancer harboring episomal form of HPV16. PLoS One. 2023. 18. 2. 1-18
  • Lauri A. Aaltonen, Federico Abascal, Adam Abeshouse, Hiroyuki Aburatani, David J. Adams, Nishant Agrawal, Keun Soo Ahn, Sung-Min Ahn, Hiroshi Aikata, Rehan Akbani, et al. Pan-cancer analysis of whole genomes. Nature. 2020. 578. 7793. 82-93
  • Farhana Ghani, Kasumi Dendo, Reiko Watanabe, Kenji Yamada, Yuki Yoshimatsu, Takashi Yugawa, Tomomi Nakahara, Katsuyuki Tanaka, Hiroshi Yoshida, Masayuki Yoshida, et al. An ex-vivo culture system of ovarian cancer faithfully recapitulating the pathological features of primary tumors. Cells. 2019. 8. 7. 644
  • Dendo K, Yugawa T, Nakahara T, Ohno SI, Goshima N, Arakawa H, Kiyono T. Induction of non-apoptotic programmed cell death by oncogenic RAS in human epithelial cells and its suppression by MYC overexpression. Carcinogenesis. 2018. 39. 2. 202-213
  • Yuki Yoshimatsu, Tomomi Nakahara, Katsuyuki Tanaka, Yuki Inagawa, Mako Narisawa-Saito, Takashi Yugawa, Shin-ichi Ohno, Masatoshi Fujita, Hitoshi Nakagama, Tohru Kiyono. Roles of the PDZ-binding motif of HPV 16 E6 protein in oncogenic transformation of human cervical keratinocytes. CANCER SCIENCE. 2017. 108. 7. 1303-1309
ｍore...
MISC (23)：
  • 温川恭至, 大野真一, 中原知美, 藤田雅俊, 五島直樹, 清野透. 非古典的NOTCHシグナルはROCKの活性化を介して角化細胞の自己複製能を制限する. 日本分子生物学会年会プログラム・要旨集(Web). 2013. 36th. 2P-0305 (WEB ONLY)
  • Sugimoto N, Yoshida K, Tatsumi Y, Yugawa T, Narisawa-Saito M, Waga S, Kiyono T, Fujita M. Redundant and differential regulation of multiple licensing factors ensures prevention of re-replication in normal human cells. J Cell Sci. 2009. 122. 8. 1184-1191
  • Sasaki R, Narisawa-Saito M, Yugawa T, Fujita M, Tashiro H, Katabuchi H, Kiyono T. Oncogenic transformation of human ovarian surface epithelial cells with defined cellular oncogenes. Carcinogenesis. 2009. 30. 423-431
  • Yugawa T, Kiyono T. Molecular mechanisms of cervical carcinogenesis by high-risk human papillomaviruses: novel functions of E6 and E7 oncoproteins. Rev Med Virol. 2009. 19. 97-113
  • 温川恭至, 清野 透. Molecular basis of cervical carcinogenesis by high-risk human papillomaviruses. Uirusu. 2008. 58. 2. 141-154
ｍore...
Association Membership(s) (3)：
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE SOCIETY FOR VIROLOGY ,  THE JAPANESE CANCER ASSOCIATION
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page

TOP

BOTTOM