Rchr
J-GLOBAL ID:200901056774669047   Update date: Sep. 01, 2020

Takeuchi Ayako

タケウチ アヤコ | Takeuchi Ayako
Affiliation and department:
Research field  (2): Clinical pharmacy ,  Physiology
Research keywords  (6): Bリンパ球 ,  細胞生理学 ,  システム生理学 ,  心筋細胞 ,  systems physiology ,  cardiomyocyte
Research theme for competitive and other funds  (23):
  • 2019 - 2022 development of a method to analyze local organelle function in situ
  • 2019 - 2022 Elucidation of metabolism-excitation-contraction coupling in cardiomyocytes through metabolic imaging
  • 2018 - 2021 Physiological role of mitochondrial heterogeneity in ventricular myocytes
  • 2018 - 2019 Bリンパ球機能制御を司るミトコンドリア-小胞体連関の可視化
  • 2017 - 2018 新規免疫制御薬の創製を目指したリンパ球特異的ミトコンドリアCa2+トランスポートソームの解明
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Papers (45):
  • Mohammed M Islam, Ayako Takeuchi, Satoshi Matsuoka. Membrane current evoked by mitochondrial Na+-Ca2+ exchange in mouse heart. The Journal of Physiological Sciences : JPS. 2020. 70. 1. 24-24
  • Ayako Takeuchi, Satoshi Matsuoka. Integration of mitochondrial energetics in heart with mathematical modelling. The Journal of Physiology. 2020
  • Ayako Takeuchi, Bongju Kim, Satoshi Matsuoka. Physiological functions of mitochondrial Na+-Ca2+ exchanger, NCLX, in lymphocytes. Cell Calcium. 2020. 85. 102114-102114
  • Yaopeng Hu, Yubin Duan, Ayako Takeuchi, Lin Hai-Kurahara, Jun Ichikawa, Keizo Hiraishi, Tomohiro Numata, Hiroki Ohara, Gentaro Iribe, Michio Nakaya, et al. Uncovering the arrhythmogenic potential of TRPM4 activation in atrial-derived HL-1 cells using novel recording and numerical approaches. CARDIOVASCULAR RESEARCH. 2017. 113. 10. 1243-1255
  • Ryuta Saito, Ayako Takeuchi, Yukiko Himeno, Nobuya Inagaki, Satoshi Matsuoka. A simulation study on the constancy of cardiac energy metabolites during workload transition. JOURNAL OF PHYSIOLOGY-LONDON. 2016. 594. 23. 6929-6945
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MISC (11):
  • Ayako Takeuchi, Ryuta Saito, Yukiko Himeno, Satoshi Matsuoka. A Theoretical Study on the Roles of Ca2+ in the Energy Metabolite Stability during Cardiac Workload Transition. BIOPHYSICAL JOURNAL. 2017. 112. 3. 131A-131A
  • Ayako Takeuchi, Bongju Kim, Satoshi Matsuoka. Theoretical analysis of mitochondrial NCX ( NCLX) -mediated regulation of cardiac automaticity. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2013. 63. S120-S120
  • Bongju Kim, Ayako Takeuchi, Satoshi Matsuoka. Role of Mitochondrial NCX on CXCL12-Induced Chemotaxis in A20 B Lymphocytes. BIOPHYSICAL JOURNAL. 2013. 104. 2. 112A-112A
  • Bongju Kim, Ayako Takeuchi, Satoshi Matsuoka. Mitochondrial NCX controls directional migration of B lymphocyte. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2013. 63. S136-S136
  • Natascia Vedovato, Ayako Takeuchi, Pablo Artigas, Nicolas Reyes, David C. Gadsby. Gating Ion Translocation through the Na,K-ATPase Pump. BIOPHYSICAL JOURNAL. 2012. 102. 3. 407A-407A
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Books (5):
  • 生理学実習書
    南江堂 2013
  • Patch Clamp Techniques-From beginning to advanced protocols-
    Springer Protocols 2012
  • トランスポートソームの世界-膜輸送研究の源流から未来へ-
    京都廣川書店 2011
  • SYSTEM BIOENERGETICS Energy for life
    WILEY-VCH 2007
  • Control and Diseases of Sodium Dependent Transport Proteins and Ion Channels
    Elsevier Science B. V. 2000
Lectures and oral presentations  (32):
  • マウス洞房結節細胞のlocal Ca releaseに対するミトコンドリアNa/Ca交換の関与
    (日本生理学雑誌(Web) 2018)
  • シングルファイバーを用いた神経膠芽腫細胞遊走におけるミトコンドリア動態の解析
    (日本バイオマテリアル学会大会予稿集(Web) 2017)
  • Frequency-dependences of action potential and Ca2+ transient and roles of mitochondrial Na+/Ca2+ exchange in mice ventricular myocyte
    (2017 Cardiac Physiome Workshop 2017)
  • Involvement of vitamin D receptor and its related genes in the generation of rhythmic Ca transient in murine atrial myocyte-derived cell line HL-1
    (第94回日本生理学会大会 2017)
  • A simulation study on Ca<sup>2+</sup> regulation of energy metabolism in cardiac mitochondria
    (2017)
more...
Education (4):
  • 2000 - 2003 Kyoto University
  • - 2003 Kyoto University
  • 1998 - 2000 京都大学 薬学研究科 修士課程 医療薬科学専攻
  • 1994 - 1998 Kyoto University
Professional career (1):
  • Ph.D. (Kyoto University)
Work history (18):
  • 2017/04 - 現在 University of Fukui Department of Integrative and Systems Physiology, Faculty of Medical Sciences Associate Professor
  • 2013/09 - 2017/03 福井大学医学部 形態機能医科学講座 統合生理学 特命助教
  • 2009/04 - 京都大学医学研究科 生体制御医学講座 細胞機能制御学 助教
  • 2009 - Apr Assistant Professor of the Department of Physiology and Biophysics, Kyoto University Graduate School of Medicine
  • 2008/04 - 米国ロックフェラー大学 Research Associate
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Committee career (2):
  • 2018/10 - 2019/03 第9回アジア・オセアニア生理学会連合大会FAOPS2019 一般演題査読委員
  • 2018/09 - 2019/03 第9回アジア・オセアニア生理学会連合大会FAOPS2019 JGPポスターアワード委員
Awards (6):
  • 2017/03 - 福井大学研究者奨励賞(男女共同参画)
  • 2014/03 - 平成25年度 入澤宏・彩記念若手研究奨励賞 [心臓・循環分野]
  • 2013/03 - 第90回日本生理学会大会 佐川喜一賞
  • 2012/10 - Cardiac Physiome Workshop 2012 Poster Prize Winner
  • 2010/05 - 第11回日本生理学会若手奨励賞
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Association Membership(s) (6):
Society of General Physiologists ,  Biophysical Society ,  日本薬学会 ,  日本生理学会 ,  The Pharmaceutical Society of Japan ,  Physiological Society of Japan
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