Research theme for competitive and other funds (27):
2022 - 2025 ミトコンドリアCa2+動態を起点とした神経細胞機能制御の分子機序解明
2022 - 2023 Decoding molecular orchestration of dopaminergic neuronal cell death by a combination of physiological experiments and computational modelling
2022 - 2023 組織特異的なミトコンドリアCa2+動態の統合的解明
2019 - 2022 development of a method to analyze local organelle function in situ
2019 - 2022 Elucidation of metabolism-excitation-contraction coupling in cardiomyocytes through metabolic imaging
2018 - 2021 Physiological role of mitochondrial heterogeneity in ventricular myocytes
Ayako Takeuchi, Satoshi Matsuoka. A simulation study on the role of mitochondria-sarcoplasmic reticulum Ca2+ interaction in cardiomyocyte energetics during exercise. The Journal of Physiology. 2024
Yoichi Kasahara, Masataka Narukawa, Ayako Takeuchi, Makoto Tominaga, Keiko Abe, Tomiko Asakura. Molecular logic of salt taste reception in special reference to transmembrane channel-like 4 (TMC4). The Journal of Physiological Sciences. 2022. 72. 1
Ayako Takeuchi, Satoshi Matsuoka. Spatial and Functional Crosstalk between the Mitochondrial Na+-Ca2+ Exchanger NCLX and the Sarcoplasmic Reticulum Ca2+ Pump SERCA in Cardiomyocytes. International Journal of Molecular Sciences. 2022
Ayako Takeuchi, Satoshi Matsuoka. Physiological and pathophysiological roles of mitochondrial Na+-Ca2+ exchanger, NCLX, in hearts. Biomolecules. 2021. 11. 12
Yoichi Kasahara, Masataka Narukawa, Yoshiro Ishimaru, Shinji Kanda, Chie Umatani, Yasunori Takayama, Makoto Tominaga, Yoshitaka Oka, Kaori Kondo, Takashi Kondo, et al. TMC4 is a novel chloride channel involved in high-concentration salt taste sensation. The Journal of Physiological Sciences. 2021. 71. 1. 23-23
Yukiko Himeno, Hiroto Nomura, Wenli Zhang, Yixin Zhang, Yuttamol Muangkram, Ayako Takeuchi, Akinori Noma, Akira Amano. Contribution of KATP channels activated in ventricular myocytes to repolarization: a simulation study. The Journal of Physiological Sciences. 2024. 74. suppl2. S138-S138
Ayako Takeuchi, Satoshi Matsuoka. Physiological impacts of spatial distribution of mitochondrial Ca 2+ transporters in cardiomyocytes. The Journal of Physiological Sciences. 2024. 74. suppl2. S43-S43
Ayako Takeuchi, Satoshi Matsuoka. Distinct characteristics of mitochondrial Ca2+ dynamics in mouse heart and brain. The Journal of Physiological Sciences. 2023. 73. suppl1. S59-S59
Satoshi Matsuoka, Ayako Takeuchi, Yukari Takeda. Impact of mitochondrial Ca2+ dynamics on cardiomyocyte function. The Journal of Physiological Sciences. 2023. 73. suppl1. S11-S11
Ayako Takeuchi, Satoshi Matsuoka. Contributions of NCLX and NCX to mitochondrial Na+ -Ca 2+ exchange in mouse brain. The Journal of Physiological Sciences. 2021. 71. suppl1. S133-S133
Theoretical analyses of the roles of mitochondrial Ca2+ dynamics during exercise using an integrated model of human ventricular myocyte
(2024 Cardiac Physiome Workshop 2024)