Yamashita Tomoya

ヤマシタトモヤ | Yamashita Tomoya

Affiliation and department：
Job title： Professor

Research field (3)： Internal medicine - General , Bacteriology , Cardiology

Research keywords (5)： Vascular biology , 腸内細菌 , Immunology , Atherosclerosis , 循環器内科学

Research theme for competitive and other funds (11)：

2022 - 2025 ヒト大動脈解離におけるシングルセルRNAシークエンスによる成因解析
2022 - 2025 大動脈解離の発生と進展に好中球が与える影響の検討
2020 - 2023 Gerontological investigation of microbiome: a longitudinal estimation study
2020 - 2022 Development of new therapies using outer membrane vesicles derived from gut microbiota
2019 - 2022 循環器疾患における腸内細菌叢の役割の解明と新規治療標的の探索

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Papers (103)：

Shintaro Takeda, Takuo Emoto, Tomoya Yamashita, Hiroyuki Yamamoto, Tomofumi Takaya, Takahiro Sawada, Takeshi Yoshida, Masatoshi Inoue, Yuya Suzuki, Tomoyo Hamana, et al. Single-Cell RNA Sequencing Reveals an Immune Landscape of CD4+ T Cells in Coronary Culprit Plaques With Acute Coronary Syndrome in Humans-Brief Report. Arteriosclerosis, thrombosis, and vascular biology. 2024. 44. 5. 1135-1143
Satoshi WATANABE, Naofumi YOSHIDA, Kairi BABA, Hiroyuki YAMASAKI, Natsuko O. SHINOZAKI, Masato OGAWA, Tomoya YAMASHITA, Aya K. TAKEDA. Gut microbial stability in older Japanese populations: insights from the Mykinso cohort. Bioscience of Microbiota, Food and Health. 2024. 43. 1. 64-72
Sayo Horibe, Takuo Emoto, Taiji Mizoguchi, Toru Tanaka, Shoji Kawauchi, Naoto Sasaki, Tomoya Yamashita, Koji Ikeda, Noriaki Emoto, Ken-ichi Hirata, et al. Endothelial senescence alleviates cognitive impairment in a mouse model of Alzheimer's disease. Glia. 2023
Hiroyuki Yamamoto, Tomofumi Takaya, Takuo Emoto, Shintaro Takeda, Naofumi Yoshida, Takahiro Sawada, Tomoya Yamashita, Ken-ichi Hirata, Hiroya Kawai. Acute Coronary Syndrome Due to Intraplaque Hemorrhage in a Post-gastrectomy Patient with a Latent Severe Glycemic Disorder. Internal Medicine. 2023. 62. 3. 399-403
Ryohei Shinohara, Hitomi Nakashima, Takuo Emoto, Tomoya Yamashita, Yoshihiro Saito, Naofumi Yoshida, Taishi Inoue, Katsuhiro Yamanaka, Kenji Okada, Ken-ichi Hirata. Gut Microbiota Influence the Development of Abdominal Aortic Aneurysm by Suppressing Macrophage Accumulation in Mice. Hypertension. 2022. 79. 12. 2821-2829

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MISC (184)：

平田健一, 山下智也. 腸内細菌と心血管疾患. 日本内科学会雑誌. 2024. 113. 臨増. 82-85
江本拓央, 井上大志, 山中勝弘, 山下智也, 岡田健次, 平田健一. 血管疾患のゲノム、トランスクリプトーム解析シングルセル解析を用いた、免疫をターゲットとした大動脈解離治療法開発. 脈管学. 2023. 63. Suppl. S124-S124
山下智也. 腸内細菌と循環器疾患. 腸内フローラシンポジウム. 2023. 30. 47-56
山下智也. 【消化管細菌と全身性疾患】循環器系疾患と腸内細菌叢ならびにその関連代謝物との関係. 臨床化学. 2023. 52. 3. 170-178
江本拓央, 山下智也, 平田健一. シングルセル解析で解き明かすプラーク不安定化メカニズム. 日本動脈硬化学会総会プログラム・抄録集. 2023. 55回. 108-108

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Patents (1)：

リポ多糖制御性腸内細菌及びその用途

Books (10)：

Current Therapy in Cardiovascular Diseases
2020
Atherosclerosis in clinics
2019
Gut microbiota ~Another organ for controlling human health and disease~
2019
Molecular Cardiology for developing new clinical medicine
2019
Gut and oral microbiota in systemic diseases
シーエムシー出版 2015

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Lectures and oral presentations (165)：

Intestinal microbiota in heart failure
(84th Annual Scientific Meeting of Japanese Circulatory Society 2020)
Gut microbiome and atherosclerosis
(2019)
糖尿病薬の腸内細菌への影響と腸内細菌叢から見た動脈硬化予防
(第53回糖尿病のの進歩 2019)
冠動脈疾患患者大腸フローラモデルによる候補投与物の調査
(日本農芸化学会2019年度大会 2019)
The Correlation between Circulating Intermediate CD14++CD16+Monocytes and Atrial Electrical Remodeling in Atrial Fibrillation Patients
(第83回日本循環器学会学術集会 2019)

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Education (1)：

- 2000 神戸大学大学院医学研究科博士課程内科学系専攻修了

Professional career (1)：

博士(医学) (神戸大学)

Awards (2)：

2016/07 - 日本動脈硬化学会五島雄一郎賞 Intestinal Immunity and Gut Microbiota in Atherogenesis.
2011/04 - American Heart Association 2011 Daniel Steinberg New Investigator Award in Atherosclerosis/Lipoproteins

Association Membership(s) (4)：

American Heart Association , JAPAN ATHEROSCLEROSIS SOCIETY , 日本循環器学会 , 日本内科学会

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