Yugi Katsuyuki

ユギカツユキ | Yugi Katsuyuki

Affiliation and department：
Job title： Senior Scientist
Other affiliations (2)：

Homepage URL (1)： https://www.riken.jp/research/labs/ims/integr_cell_sys/

Research field (2)： Systems genomics , Biological, health, and medical informatics

Research keywords (4)： mathematical modeling , systems biology , metabolism , trans-omics

Research theme for competitive and other funds (9)：

2022 - 2028 Data-driven Darwinian medicine approach for exploring shared metabolic regulatory networks between seasonal affective disorder and hibernation
2018 - 2023 Development of next-generation trans-omics technologies for multi-timescale metabolic regulation in psychiatric disorders
2015 - 2019 トランスオミクス解析による多剤併用療法の合理的設計と多因子代謝疾患の制御
2015 - 2019 Identification and control of disease-specific network by trans-omic analysis
2008 - 2010 Design and construction of genetic relaxation oscillators based on systems and synthetic biology.

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Papers (39)：

Yunfan Bai, Keigo Morita, Toshiya Kokaji, Atsushi Hatano, Satoshi Ohno, Riku Egami, Yifei Pan, Dongzi Li, Katsuyuki Yugi, Saori Uematsu, et al. Trans-omic analysis reveals opposite metabolic dysregulation between feeding and fasting in liver associated with obesity. iScience. 2024. 27. 3. 109121-109121
Kozo Nishida, Junichi Maruyama, Kazunari Kaizu, Koichi Takahashi, Katsuyuki Yugi. Transomics2cytoscape: an automated software for interpretable 2.5-dimensional visualization of trans-omic networks. NPJ systems biology and applications. 2024. 10. 1. 16-16
Tadashi Takeuchi, Tetsuya Kubota, Yumiko Nakanishi, Hiroshi Tsugawa, Wataru Suda, Andrew Tae-Jun Kwon, Junshi Yazaki, Kazutaka Ikeda, Shino Nemoto, Yoshiki Mochizuki, et al. Gut microbial carbohydrate metabolism contributes to insulin resistance. Nature. 2023. 621. 7978. 389-395
Toshiya Kokaji, Miki Eto, Atsushi Hatano, Katsuyuki Yugi, Keigo Morita, Satoshi Ohno, Masashi Fujii, Ken-Ichi Hironaka, Yuki Ito, Riku Egami, et al. In vivo transomic analyses of glucose-responsive metabolism in skeletal muscle reveal core differences between the healthy and obese states. Scientific reports. 2022. 12. 1. 13719-13719
Akira Terakawa, Yanhui Hu, Toshiya Kokaji, Katsuyuki Yugi, Keigo Morita, Satoshi Ohno, Yifei Pan, Yunfan Bai, Andrey A. Parkhitko, Xiaochun Ni, et al. Trans-omics analysis of insulin action reveals a cell growth subnetwork which co-regulates anabolic processes. iScience. 2022. 25. 5. 104231-104231

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MISC (8)：

小鍛治俊也, 幡野敦, 柚木克之, 黒田真也. 【マルチオミクスを使って得られた最新知見糖尿病・がん・腸内細菌研究における実例と解析法】マウス肝臓における肥満特異的な代謝制御トランスオミクスネットワーク構築. 実験医学. 2020. 38. 8. 1289-1294
Katsuyuki Yugi, Satoshi Ohno, James R. Krycer, David E. James, Shinya Kuroda. Rate-oriented trans-omics: integration of multiple omic data on the basis of reaction kinetics. Current Opinion in Systems Biology. 2019. 15. 109-120
Katsuyuki Yugi, Shinya Kuroda. Metabolism as a signal generator across trans-omic networks at distinct time scales. Current Opinion in Systems Biology. 2018. 8. 59-66
柚木克之, Krycer James R, 平山明由, Fazakerley Daniel J, Quek Lake-Ee, Scalzo Richard, 大野聡, Hodson Mark P, 池田五月, 庄司二葉, et al. 動的13C-メタボロミクスおよびリン酸化プロテオミクスの統合解析により明らかとなった脂肪細胞の代謝プライミング機構. JSBMS Letters. 2017. 42. Suppl. 108-108
Trans-omics : reconstruction of a global network from multiple 'omic' data. 2015. 73. 5. 392-394

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Patents (1)：

Books (1)：

Lectures and oral presentations (6)：

健常および肥満マウスの肝臓および筋肉におけるグルコース負荷に対する代謝変動の網羅的解析
(日本生化学会大会・日本分子生物学会年会合同大会講演要旨集 2015)
Transomics analysis of insulin action
(Abstracts for Annual Meeting of Japanese Proteomics Society 2014)
RNA-Seqを用いたインスリン依存的選択的スプライシング変動の網羅的解析
(日本生化学会大会プログラム・講演要旨集 2013)
Kinetic Modelling of Energy Metabolism in Mitochondria
(GI 1999)
E-CELLプロジェクトの概要細胞内全代謝の包括的シミュレーションに向けて
(日本分子生物学会年会プログラム・講演要旨集 1998)

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Professional career (1)：

Work history (7)：

2020/07 - RIKEN Center for Integrative Medical Sciences Team Leader
2017/01 - 2020/06 RIKEN Center for Integrative Medical Sciences Senior Scientist
2015/10 - 2019/03 Japan Science and Technology Agency PRESTO PRESTO Researcher
2017/04 - Keio University Graduate School of Media and Governance Project Associate Professor
2013/07 - 2016/12 The University of Tokyo Graduate School of Science Department of Biophysics and Biochemistry Research Associate

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Committee career (6)：

2024 - ECCB2024 (23st European Conference on Computational Biology) Program Committee Reviewer
2022 - ECCB2022 (21st European Conference on Computational Biology) Programme Committee Reviewer
2019/01 - 2019/12 Molecular Biology Society of Japan Poster Committee Member
2018/11 - 2019/11 日本分子生物学会第41回日本分子生物学会年会ポスターディスカッサー
2018/04 - 2019/11 International Conference on Systems Biology 2019 Organizing committee core member

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Awards (1)：

2020/07 - Mishima Kaiun Memorial Foundation Mishima Kaiun Memorial Foundation Award

Association Membership(s) (5)：

日本薬理学会 , 日本プロテオーム学会 , 日本神経科学学会 , International Society for Systems Biology , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN

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