Rchr
J-GLOBAL ID：200901057936608094
Update date: May. 01, 2024
Inoue Asuka
イノウエ アスカ | Inoue Asuka
Affiliation and department：
Tohoku University Graduate School of Pharmaceutical Sciences
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Detailed information
Job title：
Professor
Other affiliations (1)：
Kyoto University
Graduate School of Pharmaceutical Sciences Professor
Research field (3)：
Pharmacology
, Pharmaceuticals - health and biochemistry
, Functional biochemistry
Research keywords (1)：
GPCR
Research theme for competitive and other funds (14)：
2009 - 現在 Development of a nobel assay system to detect activation of G protein-coupled receptors (GPCRs)
2008 - 現在 体毛形成におけるリゾホスファチジン酸の生理機能の解析
2021 - 2026 Structural dynamics of GPCR in cells
2021 - 2025 Manipulation of G12/13 signaling and and drug development strategy
2021 - 2024 Multi-scale platform for untangling physiological complexity
2021 - 2024 オピオイド受容体の網羅的シグナル解析による薬理経路の同定
2020 - 2023 新規リゾリン脂質の機能解明とその作用標的の探索
2018 - 2023 Study of drug discovery and biomarker for depression based on glial antidepressant receptor (LPA1)
2017 - 2020 Signaling basis of GPCR-acting drugs and their therapeutic mechanisms
2016 - 2018 Understanding lipid-regulated TRP channels and their roles in thermal biology
2014 - 2017 A role of lysophosphatidic acid signaling in male organ
2012 - 2014 Screening for ligands of G protein-coupled receptors using the newly developed TGFalpha shedding assay
2009 - 2010 Lysophosphatidic acid regulates hair follicle development
2006 - 2008 新規リン脂質分解酵素ホスホリパーゼA1のノックアウトマウスを用いた生理機能の解明
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Papers (235)：
Kosuke Doi, Kouki Kawakami, Tatsuya Ikuta, Asuka Inoue. A cAMP-biosensor-based assay for measuring plasma arginine-vasopressin levels. Scientific reports. 2024. 14. 1. 9453-9453
Masumi Oka, Sohta Akaki, Osamu Ohno, Maho Terasaki, Yuho Hamaoka-Tamura, Michiko Saito, Shinichi Kato, Asuka Inoue, Junken Aoki, Kenji Matsuno, et al. Suppression of Mast Cell Activation by GPR35: GPR35 Is a Primary Target of Disodium Cromoglycate. The Journal of pharmacology and experimental therapeutics. 2024. 389. 1. 76-86
Tharindunee Jayakody, Asuka Inoue, Srinivasaraghavan Kannan, Gaku Nakamura, Kouki Kawakami, Krishan Mendis, Thanh-Binh Nguyen, Jianguo Li, Deron R Herr, Chandra S Verma, et al. Mechanisms of biased agonism by Gαi/o-biased stapled peptide agonists of the relaxin-3 receptor. Science signaling. 2024. 17. 823. eabl5880
Ryoji Kise, Asuka Inoue. GPCR signaling bias: an emerging framework for opioid drug development. The Journal of Biochemistry. 2024. 175. 4. 367-376
Dayana Abboud, Clauda Abboud, Asuka Inoue, Jean-Claude Twizere, Julien Hanson. Basal interaction of the orphan receptor GPR101 with arrestins leads to constitutive internalization. Biochemical Pharmacology. 2024. 220. 116013-116013
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MISC (229)：
中村楽, 桑原莉来, 川上耕季, 井上飛鳥. GPCRとβアレスチンの結合多様性と機能的役割の解析. 日本生化学会大会(Web). 2023. 96th
九川真衣, 木瀬亮次, 福田昌弘, 川上耕季, 松井俊貴, 小林和弘, 井上飛鳥, 加藤英明, 加藤英明, 加藤英明. 遊離脂肪酸受容体(FFAR)の脂肪酸受容における鎖長選択性の解明. 日本生化学会大会(Web). 2023. 96th
福永彩美, 川上耕季, 小柳淳暉, 福田昌弘, 小林和弘, 松井俊貴, SCOTT Daniel J., 井上飛鳥, 加藤英明, 加藤英明. 構造生物学から見たバソプレシン・オキシトシンの分子理解. バソプレシン・オキシトシン研究会プログラム・抄録集. 2023. 33rd
新井大輝, 辰己茉菜絵, 生田達也, 川上耕季, 井上飛鳥. Analysis of αN helix function in Gα protein activation. 日本薬学会年会要旨集(Web). 2023. 143rd
中村楽, 川上耕季, 生田達也, 井上飛鳥. Analysis of biased-signal creation substrates and mechanisms in GPCRs. 日本薬学会年会要旨集(Web). 2023. 143rd
ｍore...
Professional career (1)：
Ph.D. (The University of Tokyo)
Work history (2)：
2024/04 - 現在 Kyoto University Graduate School of Pharmaceutical Sciences Professor
2022/04 - 現在 Tohoku University Graduate School of Pharmaceutical Sciences Professor
Association Membership(s) (2)：
日本薬学会
, 日本生化学会
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