J-GLOBAL ID:200901057936608094   Update date: Sep. 01, 2020

Inoue Asuka

イノウエ アスカ | Inoue Asuka
Affiliation and department:
Job title: Research Associate
Research field  (3): Pharmacology ,  Pharmaceuticals - health and biochemistry ,  Functional biochemistry
Research keywords  (1): GPCR
Research theme for competitive and other funds  (2):
  • 2009 - 現在 Development of a nobel assay system to detect activation of G protein-coupled receptors (GPCRs)
  • 2008 - 現在 体毛形成におけるリゾホスファチジン酸の生理機能の解析
Papers (142):
  • Signe Mathiasen, Tiago Palmisano, Nicole A Perry, Hannah M Stoveken, Alex Vizurraga, Dyke P McEwen, Najeah Okashah, Tobias Langenhan, Asuka Inoue, Nevin A Lambert, et al. G12/13 is activated by acute tethered agonist exposure in the adhesion GPCR ADGRL3. Nature chemical biology. 2020
  • Michael W Boesgaard, Kasper Harpsøe, Michelle Malmberg, Christina R Underwood, Asuka Inoue, Jesper M Mathiesen, Gabriele M König, Evi Kostenis, David E Gloriam, Hans Bräuner-Osborne. Delineation of molecular determinants for FR900359 inhibition of Gq/11 unlocks inhibition of Gαs. The Journal of biological chemistry. 2020
  • Daniel Hilger, Kaavya Krishna Kumar, Hongli Hu, Mie Fabricius Pedersen, Evan S O'Brien, Lise Giehm, Christine Jennings, Gözde Eskici, Asuka Inoue, Michael Lerch, et al. Structural insights into differences in G protein activation by family A and family B GPCRs. Science (New York, N.Y.). 2020. 369. 6503
  • Sho Nakamura, Misa Sayama, Akiharu Uwamizu, Sejin Jung, Masaya Ikubo, Yuko Otani, Kuniyuki Kano, Jumpei Omi, Asuka Inoue, Junken Aoki, et al. Non-naturally-occurring Regio Isomer of Lysophosphatidylserine Exhibits Potent Agonistic Activity Towards G Protein-coupled Receptors. Journal of medicinal chemistry. 2020
  • Mithu Baidya, Punita Kumari, Hemlata Dwivedi-Agnihotri, Shubhi Pandey, Madhu Chaturvedi, Tomasz Maciej Stepniewski, Kouki Kawakami, Yubo Cao, Stéphane A Laporte, Jana Selent, et al. Key phosphorylation sites in GPCRs orchestrate the contribution of β-Arrestin 1 in ERK1/2 activation. EMBO reports. 2020. e49886
MISC (183):
Association Membership(s) (2):
日本薬学会 ,  日本生化学会
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