Rchr
J-GLOBAL ID：200901058148419902   Update date: Mar. 17, 2025

Tanaka Kozo

タナカ コウゾウ | Tanaka Kozo
Affiliation and department：
Tohoku University Department of Molecular Oncology, Division of Cancer Control, Institute of Development, Aging and Cancer

About Tohoku University Department of Molecular Oncology, Division of Cancer Control, Institute of Development, Aging and Cancer


Job title： Professor
Homepage URL  (2)： http://www2.idac.tohoku.ac.jp/dep/molonc/index.html ,  http://www2.idac.tohoku.ac.jp/dep/molonc/pg40.html
Research field  (3)： Pathobiochemistry ,  Cell biology ,  Molecular biology
Research keywords  (4)： chromosomal instability ,  chromosome segregation ,  Molecular oncology ,  Cellular biology
Research theme for competitive and other funds  (27)：
  • 2007 - 現在 Mechanisms of accurate chromosome segregation
  • 2007 - 現在 Mitosis-targeted anti-cancer therapies
  • 2023 - 2025 分裂期染色体の可塑性が染色体分配に及ぼす影響の解明
  • 2022 - 2025 がん細胞の染色体不安定性の原因としての染色体オシレーション減弱機構の解明
  • 2022 - 2024 Role of oxidative stress in chromosomal insability with age
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Papers (95)：
  • Binghao Chai, Christoforos Efstathiou, Muntaqa S. Choudhury, Kinue Kuniyasu, Saakshi Sanjay Jain, Alexia-Cristina Maharea, Kozo Tanaka, Viji M. Draviam. Multi-SpinX: An advanced framework for automated tracking of mitotic spindles and kinetochores in multicellular environments. Computers in Biology and Medicine. 2025
  • Shin-ichiro Kanno, Takayasu Kobayashi, Reiko Watanabe, Akihiro Kurimasa, Kozo Tanaka, Akira Yasui, Ayako Ui. Armadillo domain of ARID1A directly interacts with DNA-PKcs to couple chromatin remodeling with nonhomologous end joining (NHEJ) pathway. Nucleic Acids Research. 2025
  • Yudai Ishikawa, Hirotaka Fukue, Runa Iwakami, Masanori Ikeda, Kenji Iemura, Kozo Tanaka. Fibrous corona is reduced in cancer cell lines that attenuate microtubule nucleation from kinetochores. Cancer Science. 2025
  • Yujiro Yoshizaki, Yunosuke Ouchi, Dicky Kurniawan, Eisuke Yumoto, Yuki Yoneyama, Faiza Ramadhani Rizqullah, Hiyori Sato, Mirjam Hanako Sarholz, Toyoaki Natsume, Masato T Kanemaki, et al. CHAMP1 premature termination codon mutations found in individuals with intellectual disability cause a homologous recombination defect through haploinsufficiency. Scientific reports. 2024. 14. 1. 31904-31904
  • Sharmin Naher, Kenji Iemura, Satoshi Miyashita, Mikio Hoshino, Kozo Tanaka, Shinsuke Niwa, Jin-Wu Tsai, Takako Kikkawa, Noriko Osumi. Kinesin-like motor protein KIF23 maintains neural stem and progenitor cell pools in the developing cortex. The EMBO Journal. 2024
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MISC (57)：
  • 家村顕自, 田中耕三. Cancer secretome induces chromosomal instability. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
  • 池田真教, 鈴木康弘, 田中耕三, 佐藤靖史. Understanding of a spatiotemporal regulation of α-tubulin detyrosination. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
  • 家村顕自, 田中耕三. Mitotic chromosome oscillation maintains chromosomal stability. 日本細胞生物学会大会(Web). 2021. 73rd
  • 家村顕自, 田中耕三. 分裂期染色体動態異常を介した染色体不安定性の発生機構. 日本癌学会学術総会抄録集(Web). 2021. 80th
  • 家村顕自, 田中耕三. Chromosome oscillation-mediated robust equal segregation system is suppressed together with progression of cellular senescence. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
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Education (2)：
  • - 1997 The University of Tokyo Graduate School, Division of Medical Sciences Internal Medicine
  • - 1991 The University of Tokyo Faculty of Medicine Medaical Department
Professional career (1)：
  • 博士(医学) (The University of Tokyo)
Work history (9)：
  • 2011/03 - 現在 Department of Molecular Oncology, Institute of Development, Aging and Cancer, Tohoku University Professor
  • 2008/10 - 2011/02 Institute of Development, Aging and Cancer, Tohoku University Associate Professor
  • 2007/03 - 2008/09 東北大学特定領域研究推進支援センター Associate Professor
  • 2002/01 - 2007/02 College of Life Science, University of Dundee, UK Post-doctral research assistant
  • 1998/04 - 2001/12 広島大学原爆放射能医学研究所分子病理学研究分野 助手
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Committee career (4)：
  • 2024/10 - 現在 Japan Sarcoma Association Delegate
  • 2018/06 - 現在 Japan Society for Cell Biology Representative
  • 2015/01 - 現在 日本生化学会 評議員
  • 2010/01 - 現在 日本癌学会 評議員
Awards (1)：
  • 2001/06/09 - 広島大学医学部医学科同窓会広仁会 広島大学医学部広仁会基礎医学研究賞 相同組換え遺伝子による効率的なジーン・ターゲティング法の開発
Association Membership(s) (5)：
THE JAPANESE BIOCHEMICAL SOCIETY ,  Japan Society for Cell Biology ,  The Japanese Society of Internal Medicine ,  The Molecular Biology Society of Japan ,  日本癌学会(2010/01- 評議員)
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