Rchr
J-GLOBAL ID：200901058593093375
Update date: Apr. 15, 2024
Tsuda Sakae
ツダ サカエ | Tsuda Sakae
Affiliation and department：
Job title：
Specially Appointed Researcher/Fellow (Full time)
Homepage URL (2)：
https://www.sakaetsuda.jp/index.html
,
https://www.sakaetsuda.jp/index_e.html
Research field (1)：
Structural biochemistry
Research keywords (8)：
Structure
, X-ray
, NMR
, Structural biology
, INP
, AFP
, Ice nucleation Protein
, Antifreeze protein
Research theme for competitive and other funds (17)：
- 2024 - 2027 水の凍結を制御する水分子凝集層の開発
- 2019 - 2022 Application of hyperactive antifreeze from a cold-tolerant insect
- 2019 - 2022 Development of new cell preservation technologies utilizing antifreeze protein
- 2016 - 2019 Development of a cooling preservation method that secures the function of retinal tissue for regenerative medicine
- 2015 - 2017 Quantitative analysis of the ability of ice recrystallization inhibition of antifreeze protein
- 2011 - 2014 不凍ペプチドを用いた牛生殖細胞と初期胚の超高性能保存液の開発
- 2011 - 2014 Functional analysis and application of an effective cell-preservation peptide CPP
- 2008 - 2010 Elucidation of protein architecture and molecular evolution of microbial antifreeze proteins
- 2000 - 不凍蛋白質・氷核蛋白質の探索、分子機構解明および食品・医学・工学分野への応用
- 2000 - Antifreeze protein - from structural basis to technological applications -
- 1992 - 1992 NMRを用いたトロポニンCとトロポニンエペプチドの相互作用の研究
- 1992 - 1992 カルシウム結合タンパク質の構造のNMRによる研究
- 1990 - 1992 Development of New Methods for NMR of Spin*1 in Solids
- 1991 - 1991 マストパランを結合したトロポニンCの2次元NMRによる高次構造解析
- 1989 - 1990 Study of Sol-gel Transition using Various NMR Techniques
- 1988 - 1988 常磁性金属イオンをプローブとする高分子金属錯体の構造とゆらぎの研究
- 1986 - 1988 Characterization of Polymers by Use of New NMR Techniques
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Papers (105)：
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Yue Yang, Akari Yamauchi, Sakae Tsuda, Masahiro Kuramochi, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai. The ice-binding site of antifreeze protein irreversibly binds to cell surface for its hypothermic protective function. Biochemical and Biophysical Research Communications. 2023
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Masahiro Kuramochi, Tatsuya Arai, Kazuhiro Mio, Sakae Tsuda, Yuji C Sasaki. The effect of ice-binding proteins on the cryopreservation of Caenorhabditis elegans. microPublication Biology. 2023
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彩加林 山内, 栄 津田. 昆虫由来不凍タンパク質の氷結晶結合機能と細胞保護機能. 低温科学. 2023
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栄 津田, 達也 新井. 不凍タンパク質の構造と機能. 低温科学. 2023
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Ryo Okamoto, Ryo Orii, Hiroyuki Shibata, Yuta Maki, Sakae Tsuda, Yasuhiro Kajihara. Regulating Antifreeze Activity through Water: Latent Functions of the Sugars of Antifreeze Glycoprotein Revealed by Total Chemical Synthesis. Chemistry - A European Journal. 2023. 29. 21. e202203553
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MISC (202)：
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倉持昌弘, 新井達也, 三尾和弘, 津田栄, 佐々木裕次. Ice-binding proteins improve the survival rate of the nematode Caenorhabditis elegans at freezing and cold environments. アグリバイオ. 2023. 6. 14
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倉持昌弘, 新井達也, 三尾和弘, 津田栄, 佐々木裕次. Ice-Binding Proteins in maintaining biological activity in frozen and sub-zero environments. アグリバイオ. 2023. 7. 5
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新井達也, 新井達也, 楊越, 津田栄, 三尾和弘, 佐々木裕次, 佐々木裕次. 回折X線明滅法による不凍タンパク質分子表面の凍結水の動態観察. 日本蛋白質科学会年会プログラム・要旨集. 2023. 23rd (CD-ROM)
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倉持昌弘, 新井達也, 三尾和弘, 津田栄, 佐々木裕次. Acquiring freezing and cold tolerance: The role of structure-specific functions in Ice-Binding Protein molecules. アグリバイオ. 2023. 7. 10
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下谷祐平, 新井達也, 三尾和弘, 津田栄, 佐々木裕次, 倉持昌弘. Cryopreservation effects of C. elegans expressing ice-binding proteins. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
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Patents (12)：
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生体材料保護用ペプチド
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南極産子嚢菌の産生する新規不凍タンパク質
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不凍タンパク質を用いる多孔体の製造方法
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水又は含水物の凍結を促進するための材料
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不凍タンパク質混合物
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Books (5)：
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Functions and Applications of Antifreeze Preotein
2018 ISBN:9784781313399
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タンパク質の辞典
朝倉書店 2008 ISBN:9784254171280
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TANPAKUSITSU-NO-JITEN (Japanese)
ASAKURA SHUPPAN 2008 ISBN:9784254171280
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産総研のすごい仕事
日系BP出版センター 2006 ISBN:9784861530067
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SANSOUKEN-NO-SUGOI-SHIGOTO
NIKKEI BP SHUPPAN Center 2006 ISBN:9784861530067
Lectures and oral presentations (78)：
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不凍タンパク質とは何か?
(第74回日本生物工学会大会 2022)
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Fish ice-binding proteins differently function at higher concentrations
(2022)
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不凍タンパク質/凍ってもおいしいのはどうして?冷凍物の品質を向上させる技術
(STEAMライブラリー・未来の教室 2022)
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Ice and Antifreeze Protein - How does water freezes? -
(Cryopreservation Conference 2021 2021)
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What is Antifreeze Protein? - from basic to application -
(61st Summer Seminar of Life Science 2021)
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Works (2)：
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Editorial Board Member of Scientific Reports (nature.com)
2019 - 現在
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論文審査員: Tibs,Biochemistry, J.Biochem., J.Polym.Sci.,...,
Education (2)：
- 北海道大学大学院理学研究科生物科学専攻
- Graduate School of Hokkaido University
Professional career (1)：
Work history (3)：
- 2022/04 - 現在 The University of Tokyo Graduate School of Frontier Sciences Specially Appointed Researcher/Fellow (Full time)
- 2003/04 - 現在 Faculty of Life Science, Hokkaido University Transdisciplinary Life Science Course Professor
- 2013/04 - 2022/03 National Institute of Advanced Industrial Science and Technology Institute of Bioprocessing Chief Senior Researcher
Committee career (4)：
- 2019/01 - 現在 Editorial Board Member of Scientific Reports
- 2016/04 - 現在 日本低温生物工学会 総務理事
- 2011/04 - 現在 氷結晶結合蛋白質国際会議 コア組織委員
- Council member of Japanese Society for Cryobiology and Cryotechnology
Awards (7)：
- 2020/05 - Japanese Society for Cryobiology and Cryotechnology Society Award Functional analysis of antifreeze protein toward its practical applications
- 2000 - 研究優秀者表彰 通商産業省工業技術院 工業技術院長賞
- 2000 - 研究優秀者表彰 北海道工業技術研究所 所長賞
- 2000 - "AIST President Award" for excellence for work regarding NMR analysis of the structure-function-relationship of low-temparture biomolecules (Koji Kajiwara, Ph.D.).
- 2000 - Director Award" for excellence for work regarding low-temperature-structure determination of apo-troponin C from Hokkaido National Industrial Research Institute (HNIRI) (Tatsuo Katsura, Ph.D.).
- 1996 - John Baldo 学術奨励賞(University of Alberta, CA)
- 1996 - "John Baldo Award" for excellence for work regarding apo- and Ca2+-bound troponin C from University of Alberta (Prof. John Baldo and Brian D. Sykes), Canada.
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Association Membership(s) (6)：
アメリカ生化学会
, 日本生物物理学会
, 日本蛋白質科学会
, American Society of Biochemistry and Molecular Biology (ASBMB)
, Japanese Society for Cryobiology and Cryotechnology
, Protein Science Society of Japan
