Tsuda Sakae

ツダサカエ | Tsuda Sakae

Affiliation and department：
Job title： Academic Researcher/Fellow (Full-time)
Homepage URL (2)： https://www.sakaetsuda.jp/index.html , https://www.sakaetsuda.jp/index_e.html

Research field (1)： Structural biochemistry

Research keywords (8)： Structure , X-ray , NMR , Structural biology , INP , AFP , Ice nucleation Protein , Antifreeze protein

Research theme for competitive and other funds (17)：

2024 - 2027 水の凍結を制御する水分子凝集層の開発
2019 - 2022 Application of hyperactive antifreeze from a cold-tolerant insect
2019 - 2022 Development of new cell preservation technologies utilizing antifreeze protein
2016 - 2019 Development of a cooling preservation method that secures the function of retinal tissue for regenerative medicine
2015 - 2017 Quantitative analysis of the ability of ice recrystallization inhibition of antifreeze protein

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Papers (107)：

Anika T Rahman, Yasushi Ohyama, Sakae Tsuda, Hidemasa Kondo. Evaluation of Ice Recrystallization Inhibition of Ice-Binding Proteins by Monitoring Specific Ice Crystals. Methods in molecular biology (Clifton, N.J.). 2024. 2730. 93-100
Yue Yang, Akari Yamauchi, Sakae Tsuda, Masahiro Kuramochi, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai. The ice-binding site of antifreeze protein irreversibly binds to cell surface for its hypothermic protective function. Biochemical and Biophysical Research Communications. 2023
Masahiro Kuramochi, Tatsuya Arai, Kazuhiro Mio, Sakae Tsuda, Yuji C Sasaki. The effect of ice-binding proteins on the cryopreservation of Caenorhabditis elegans. microPublication Biology. 2023
彩加林山内, 栄津田. 昆虫由来不凍タンパク質の氷結晶結合機能と細胞保護機能. 低温科学. 2023
栄津田, 達也新井. 不凍タンパク質の構造と機能. 低温科学. 2023

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MISC (202)：

倉持昌弘, 新井達也, 三尾和弘, 津田栄, 佐々木裕次. Ice-binding proteins improve the survival rate of the nematode Caenorhabditis elegans at freezing and cold environments. アグリバイオ. 2023. 6. 14
倉持昌弘, 新井達也, 三尾和弘, 津田栄, 佐々木裕次. Ice-Binding Proteins in maintaining biological activity in frozen and sub-zero environments. アグリバイオ. 2023. 7. 5
新井達也, 新井達也, 楊越, 津田栄, 三尾和弘, 佐々木裕次, 佐々木裕次. 回折X線明滅法による不凍タンパク質分子表面の凍結水の動態観察. 日本蛋白質科学会年会プログラム・要旨集. 2023. 23rd (CD-ROM)
倉持昌弘, 新井達也, 三尾和弘, 津田栄, 佐々木裕次. Acquiring freezing and cold tolerance: The role of structure-specific functions in Ice-Binding Protein molecules. アグリバイオ. 2023. 7. 10
下谷祐平, 新井達也, 三尾和弘, 津田栄, 佐々木裕次, 倉持昌弘. Cryopreservation effects of C. elegans expressing ice-binding proteins. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th

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Patents (12)：

生体材料保護用ペプチド
南極産子嚢菌の産生する新規不凍タンパク質
不凍タンパク質を用いる多孔体の製造方法
水又は含水物の凍結を促進するための材料
不凍タンパク質混合物

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Books (5)：

Functions and Applications of Antifreeze Preotein
2018 ISBN:9784781313399
タンパク質の辞典
朝倉書店 2008 ISBN:9784254171280
TANPAKUSITSU-NO-JITEN (Japanese)
ASAKURA SHUPPAN 2008 ISBN:9784254171280
産総研のすごい仕事
日系BP出版センター 2006 ISBN:9784861530067
SANSOUKEN-NO-SUGOI-SHIGOTO
NIKKEI BP SHUPPAN Center 2006 ISBN:9784861530067

Lectures and oral presentations (78)：

不凍タンパク質とは何か?
(第74回日本生物工学会大会 2022)
Fish ice-binding proteins differently function at higher concentrations
(2022)
不凍タンパク質/凍ってもおいしいのはどうして?冷凍物の品質を向上させる技術
(STEAMライブラリー・未来の教室 2022)
Ice and Antifreeze Protein - How does water freezes? -
(Cryopreservation Conference 2021 2021)
What is Antifreeze Protein? - from basic to application -
(61st Summer Seminar of Life Science 2021)

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Works (2)：

Editorial Board Member of Scientific Reports (nature.com)
2019 - 現在
論文審査員: Tibs,Biochemistry, J.Biochem., J.Polym.Sci.,...,

Education (2)：

北海道大学大学院理学研究科生物科学専攻
Graduate School of Hokkaido University

Professional career (1)：

Doctor of Science (Hokkaido University)

Work history (4)：

2024/10 - 現在 Hokkaido University Faculty of Advanced Life Science Academic Researcher/Fellow (Full-time)
2022/04 - 現在 The University of Tokyo Graduate School of Frontier Sciences Specially Appointed Researcher/Fellow (Full time)
2003/04 - 2024/09 Faculty of Life Science, Hokkaido University Transdisciplinary Life Science Course Professor
2013/04 - 2022/03 National Institute of Advanced Industrial Science and Technology Institute of Bioprocessing Chief Senior Researcher

Committee career (4)：

2019/01 - 現在 Editorial Board Member of Scientific Reports
2016/04 - 現在日本低温生物工学会総務理事
2011/04 - 現在氷結晶結合蛋白質国際会議コア組織委員
Council member of Japanese Society for Cryobiology and Cryotechnology

Awards (7)：

2020/05 - Japanese Society for Cryobiology and Cryotechnology Society Award Functional analysis of antifreeze protein toward its practical applications
2000 - 研究優秀者表彰通商産業省工業技術院工業技術院長賞
2000 - 研究優秀者表彰北海道工業技術研究所所長賞
2000 - "AIST President Award" for excellence for work regarding NMR analysis of the structure-function-relationship of low-temparture biomolecules (Koji Kajiwara, Ph.D.).
2000 - Director Award" for excellence for work regarding low-temperature-structure determination of apo-troponin C from Hokkaido National Industrial Research Institute (HNIRI) (Tatsuo Katsura, Ph.D.).

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Association Membership(s) (6)：

アメリカ生化学会 , 日本生物物理学会 , 日本蛋白質科学会 , American Society of Biochemistry and Molecular Biology (ASBMB) , Japanese Society for Cryobiology and Cryotechnology , Protein Science Society of Japan

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