Rchr
J-GLOBAL ID：200901059438974647   Update date: May. 19, 2024

Tsuchiya Megumi

ツチヤ メグミ | Tsuchiya Megumi
Research field  (3)： Molecular biology ,  Cell biology ,  Obstetrics and gynecology
Research keywords  (12)： 遺伝子導入 ,  抗ウイルス薬 ,  Autopagy Recptor ,  Protein degradation ,  SUMO化修飾 ,  クロマチン ,  転写制御 ,  転写因子 ,  卵巣 ,  生殖腺 ,  性分化 ,  ゴナドトロピンレセプター
Research theme for competitive and other funds  (10)：
  • 2022 - 2025 アデノウイルスタンパク質による選択的オートファジーの抑制機構の解明
  • 2019 - 2022 Regulatory mechanism of selective autophagy complexes in nucleic acid transfection
  • 2016 - 2019 Chromatin remodeling factor ARIP4 regulates the cardiomyocyte differentiation
  • 2014 - 2017 Regulation of SUMOylation dependent chromatin remoceling in heart development
  • 2011 - 2012 転写因子Sox9の新規転写調節機構による癌細胞増殖制御の解明
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Papers (28)：
  • Mengying Cui, Koji Yamano, Kenichi Yamamoto, Hitomi Yamamoto-Imoto, Satoshi Minami, Takeshi Yamamoto, Sho Matsui, Tatsuya Kaminishi, Takayuki Shima, Monami Ogura, et al. HKDC1, a target of TFEB, is essential to maintain both mitochondrial and lysosomal homeostasis, preventing cellular senescence. Proceedings of the National Academy of Sciences of the United States of America. 2024. 121. 2. e2306454120
  • Megumi Tsuchiya, Weixia Kong, Yasushi Hiraoka, Tokuko Haraguchi, Hidesato Ogawa. TBK1 inhibitors enhance transfection efficiency by suppressing p62/SQSTM1 phosphorylation. Genes to cells : devoted to molecular & cellular mechanisms. 2023. 28. 1. 68-77
  • Ichiro Takada, Shinya Hidano, Sayuri Takahashi, Kaori Yanaka, Hidesato Ogawa, Megumi Tsuchiya, Atsushi Yokoyama, Shingo Sato, Hiroki Ochi, Tohru Nakagawa, et al. Transcriptional coregulator Ess2 controls survival of post-thymic CD4+ T cells through the Myc and IL-7 signaling pathways. The Journal of biological chemistry. 2022. 298. 9. 102342-102342
  • Megumi Tsuchiya, Hidesato Ogawa, Kento Watanabe, Takako Koujin, Chie Mori, Kazuto Nunomura, Bangzhong Lin, Akiyoshi Tani, Yasushi Hiraoka, Tokuko Haraguchi. Microtubule inhibitors identified through nonbiased screening enhance DNA transfection efficiency by delaying p62-dependent ubiquitin recruitment. Genes to cells : devoted to molecular & cellular mechanisms. 2021. 26. 9. 739-751
  • Toshiharu Fujita, Sayaka Kubo, Tatsuya Shioda, Ayaka Tokumura, Satoshi Minami, Megumi Tsuchiya, Yoshitaka Isaka, Hidesato Ogawa, Maho Hamasaki, Li Yu, et al. THOC4 regulates energy homeostasis by stabilizing TFEB mRNA during prolonged starvation. Journal of cell science. 2021. 134. 6
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MISC (53)：
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Patents (2)：
Professional career (1)：
  • Doctor(Medical)
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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