Rchr
J-GLOBAL ID:200901060052489629   Update date: Jan. 30, 2024

Kinoshita Kazuo

キノシタ カズオ | Kinoshita Kazuo
Affiliation and department:
Job title: Professor
Homepage URL  (2): http://moonbeam.sakura.ne.jp/gene/http://moonbeam.sakura.ne.jp/gene/en/
Research field  (3): Medical biochemistry ,  Immunology ,  Genetics
Research keywords  (7): enucleation ,  erythrocyte ,  ongogenesis ,  突然変異 ,  クラススイッチ ,  mutation ,  Class switch
Research theme for competitive and other funds  (21):
  • 2022 - 2026 TTC7A欠損に起因する難治性腸閉鎖症のパラログ遺伝子発現促進による治療
  • 2015 - 2017 Elucidation of erythroid differentiation using fsn mice
  • 2011 - 2015 Carcinogenesis by a mutagenic enzyme AID
  • 2008 - 2010 Mechanisms of diseases by chromosomal translocation
  • 2005 - 2009 Carcinogenesis by a genome mutator AID
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Papers (64):
  • Ryoichi Matsunuma, Shoko Sato, Jason Yongsheng Chan, Kazuo Kinoshita, Keisei Taku, Kei Yamaguchi, Ryosuke Hayami, Kazumori Arai, Makoto Suzuki, Michiko Tsuneizumi. Enrichment of Immune-Related Genes in Aggressive Primary Breast Angiosarcoma: A Case Report. Case reports in oncology. 2023. 16. 1. 455-464
  • Abigail Ekuban, Shigeyuki Shichino, Cai Zong, Frederick Adams Ekuban, Kazuo Kinoshita, Sahoko Ichihara, Kouji Matsushima, Gaku Ichihara. Transcriptome analysis of human cholangiocytes exposed to carcinogenic 1,2-dichloropropane in the presence of macrophages in vitro. Scientific reports. 2022. 12. 1. 11222-11222
  • Kazuo Kinoshita, Munehiro Uemura, Takahiro Shimizu, Shun Kinoshita, Hiroyuki Marusawa. Stepwise generation of AID knock-in and conditional knockout mice from a single gene-targeting event. International immunology. 2021. 33. 7. 387-398
  • Ryoya Takizawa, Sahoko Ichihara, Cai Zong, Kazuo Kinoshita, Toshihiro Sakurai, Akihiko Ikegami, Nathan Mise, Gaku Ichihara. 1,2-Dichloropropane induces γ-H2AX expression in human cholangiocytes only in the presence of macrophages. Toxicology letters. 2021. 349. 134-144
  • Abigail Ekuban, Cai Zong, Frederick Adams Ekuban, Yusuke Kimura, Ryoya Takizawa, Kota Morikawa, Kazuo Kinoshita, Sahoko Ichihara, Seiichiroh Ohsako, Gaku Ichihara. Role of Macrophages in Cytotoxicity, Reactive Oxygen Species Production and DNA Damage in 1,2-Dichloropropane-Exposed Human Cholangiocytes In Vitro. Toxics. 2021. 9. 6
more...
MISC (91):
Works (2):
  • ヒトAID遺伝子の変異
    1999 - 2000
  • Mutations in the human AID gene
    1999 - 2000
Education (2):
  • 1994 - 1997 Kyoto University Graduate School of Medicine Molecular Biology
  • 1986 - 1992 Kyoto University Faculty of Medicine
Professional career (1):
  • M.D., Ph. D. (Kyoto University)
Work history (7):
  • 2021/04 - 現在 Shizuoka Graduate University of Public Health Professor
  • 2020/04 - 2021/03 Shizuoka General Hospital Department of Clinical Genetics Chief Doctor
  • 2006/01 - 2020/03 Shiga Medical Center Research Institute Senior Scientist
  • 2003/04 - 2005/12 Kyoto University Graduate School of Medicine Associate Professor
  • 1997/04 - 2003/03 Kyoto University Graduate School of Medicine Assistant Professor
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Association Membership(s) (3):
Japanese Society for Gene Diagnosis and Therapy ,  Japanese Cancer Association ,  Japanese Biochemical Society
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