Research field (2):
Physiology
, Clinical pharmacy
Research keywords (3):
Artificial Organ
, Biomedical Engineering
, Tissue Engineering
Research theme for competitive and other funds (7):
2012 - 2015 Establishment of ex vivo expansion method of hematopoietic progenitor cells using 3D fixed feeder cells
2009 - 2011 Development of ex vivo expansion system of hematopoietic stem/progenitor cells using stromal cells fixed on three-dimensional scaffolds
2007 - 2008 Development of in vitro expansion method of hematopoietic progenitor/stem cells using surface molecules of stromal cells on thre
2004 - 2004 Development of tissue-engineered artificial immune system
2002 - 2003 Development of a tissue-engineered bioartificial liver utilizing immature cells
2000 - 2001 Regeneration of immature tissue (fetal liver) functions utilizing a tissue-engineering approach
1998 - 1999 肝実質細胞と非実質細胞の混合培養による肝機能の生体外再構築
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Papers (55):
Miyoshi, Hirotoshi, Abo, Kenji, Hosoya, Daiki, Matsuo, Kazuyuki, Utsumi, Yoshio. Effects of mouse fetal liver cell culture density on hematopoietic cell expansion in three-dimensional cocultures with stromal cells. The International Journal of Artificial Organs. 2022. 45. 1. 103-112
Okita, Yukari, Zheng, Ling, Kawanishi, Kunio, Miyoshi, Hirotoshi, Yanagihara, Kazuyoshi, Kato, Mitsuyasu. Polyvinyl alcohol scaffolds and supplementation support 3D and sphere culturing of human cancer cell lines by reducing apoptosis and promoting cellular proliferation. Genes to cells : devoted to molecular & cellular mechanisms. 2021. 26. 5. 336-343