Research field (3)：
Molecular biology
, Applied biofunctional and bioprocess engineering
, Applied microbiology
Research keywords (5)：
Protein engineering
, Filamentous fungi
, Transcriptome
, Bioinformatics
, Molecular biology
Research theme for competitive and other funds (17)：
2022 - 2025 革新的機能的ヒト抗体配列ーエピトープのハイスループット解析技術開発
2022 - 2025 固相培養条件下の麹菌における遺伝子の動的発現制御機構の解明とその応用
2021 - 2024 タンパク質分解により誘起されるイネ根系の可塑的反応機構の解明とその育種利用
2019 - 2023 Development of novel monoclonal antibody creation system using AI and single cell technoogy
2019 - 2022 Logical analysis of cis-element function in a gene expression regulatory mechanism
2018 - 2021 Regulatory mechanisms on phenotypic plasticity of rice root system architecture induced by cell wall dynamics
2015 - 2018 Epigenetic regulation of root phenotypic plasticity contributing drought avoidance in rice
2016 - 2018 合成生物学を指向したプロモーターデザイン技術のプラットフォーム
2012 - 2015 Understanding of molecular mechanisms regulating lateral root formation for drought stress avoidance in rice
2011 - 2015 Development and application of Giga-screening system of by-molecules using cell-free biochemical reactions
2010 - 2012 糸状菌転写因子結合配列の網羅的解析とエンジニアリング
2011 - 2012 イネの種子根および冠根メリステムの形成・維持機構
2010 - 2011 ビーズディスプレイ法を用いたプロテインキナーゼ標的基質ハイスループット探索
2009 - 2011 Toward REVERSE PROTEOMICS : a selection platform of a peptide fragment that specifically inhibits the targeted protein-protein interaction.
2009 - 2010 プロテインキナーゼ標的基質ハイスループット解析のプラットフォーム
2007 - 2010 Development and application of cell-free molecular display system
2007 - 2008 免疫細胞ネットワークのデジタル解析
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Papers (68)：
Akifumi Hosoda, Izumi Mabe, Takaaki Kojima, Yuto Nakasu, Yasuaki Niizuma. The ingestion of microplastics affects the diversity of the gut microbiome and testicular development in Japanese quail. Ecological Genetics and Genomics. 2024. 33. 100288-100288
Hiroya Oka, Takaaki Kojima, Ryuji Kato, Kunio Ihara, Hideo Nakano. Construction of transcript regulation mechanism prediction models based on binding motif environment of transcription factor AoXlnR in Aspergillus oryzae. Journal of bioinformatics and computational biology. 2024. 22. 3. 2450017-2450017
Akifumi Hosoda, Yuka Ito, Takaaki Kojima, Yki Ogata, Minami Haga, Yu Akimoto, Miki Shirasawa, Michiru Kishimoto. Impact of electrolyzed water treatment on bacterial communities in food washing processes. Ecological Genetics and Genomics. 2024. 31. 100244-100244
Beixi Jia, Teruyo Ojima-Kato, Takaaki Kojima, Hideo Nakano. Rapid and cost-effective epitope mapping using PURE ribosome display coupled with next-generation sequencing and bioinformatics. Journal of bioscience and bioengineering. 2024. 137. 4. 321-328
Mayuko Okamoto, Ryo Sasaki, Koki Ikeda, Kasumi Doi, Fumiya Tatsumi, Kenzi Oshima, Takaaki Kojima, Shusei Mizushima, Keisuke Ikegami, Takashi Yoshimura, et al. FcRY is a key molecule controlling maternal blood IgY transfer to yolks during egg development in avian species. Frontiers in Immunology. 2024. 15
加藤晃代, 加藤晃代, 中野秀雄, 兒島孝明, 永井里美. Development of robust and rapid monoclonal antibody screening technology using cell-free protein synthesis. 生物工学会誌. 2021. 99. 2
Elucidating the role of KojR in transcriptional regulation and carbon metabolism for kojic acid biosynthesis in Aspergillus oryzae
(3rd Japan-Switzerland-Germany Workshop on Biocatalysis and Bioprocess Development 2023)
Aspergillus oryzae administration to mice increases the population of Bifidobacterium spp. in intestinal microflora and represses DSS-induced colitis.
(2019)
2011/09 - 日本生物工学会 第19回生物工学論文賞 High-throughput Screening of DNA Binding Sites for Transcription Factor AmyR from Aspergillus nidulans Using DNA Beads Display System.
Association Membership(s) (4)：
Japanese Society of Enzyme Engineering
, THE SOCIETY OF CHEMICAL ENGINEERS, JAPAN
, The Society for Biotechnology, Japan
, JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY
