Research field (5):
Structural biochemistry
, Pharmaceuticals - health and biochemistry
, Molecular biology
, Environmental effects of chemicals
, Environmental effects of radiation
1995 - 1996 Joint study on nature of histone variants by gene targeting
1995 - 1995 ジーンバックアウト法によるヒストンmRNA量を一定に補償する制御機構の解明
1994 - 1994 ジーンターゲッティング法によるニワトリヒストン遺伝子群の発現制御の研究
1993 - 1993 ニワトリヒストンH2A,H2B遺伝子群の構造解析と発現制御
1992 - 1992 ニワトリヒストン遺伝子群の構造解析と発現制御
Study on Regulation of Histone Gene Experssion
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Papers (62):
Yuu Miyauchi, Haruna Koba, Madoka Sawai, Hisao Kansui, Shinji Takechi. Oxidative stress and cellular toxicity induced by dihydropyrazine: a comparative study with other Maillard reaction products. The Journal of Toxicological Sciences. 2023. 48. 5. 263-272
Madoka Sawai, Yuu Miyauchi, Takumi Ishida, Shinji Takechi. Dihydropyrazine suppresses TLR4-dependent inflammatory responses by blocking MAPK signaling in human hepatoma HepG2 cells. The Journal of Toxicological Sciences. 2022. 47. 9. 381-387
Yuu Miyauchi, Akane Kimura, Madoka Sawai, Keiko Fujimoto, Yuko Hirota, Yoshitaka Tanaka, Shinji Takechi, Peter I. Mackenzie, Yuji Ishii. Use of a Baculovirus-Mammalian Cell Expression-System for Expression of Drug-Metabolizing Enzymes: Optimization of Infection With a Focus on Cytochrome P450 3A4. Frontiers in Pharmacology. 2022. 13. 832931-832931
Yuu Miyauchi, Madoka Sawai, Takumi Ishida, Hisao Kansui, Shinji Takechi. Molecular mechanism of dihydropyrazine-induced cytotoxicity: the possibility of an independent pathway from the receptor for advanced glycation end products. The Journal of toxicological sciences. 2021. 46. 11. 509-514
Yuu Miyauchi, Shinji Takechi, Yuji Ishii. Functional Interaction between Cytochrome P450 and UDP-Glucuronosyltransferase on the Endoplasmic Reticulum Membrane: One of Post-translational Factors Which Possibly Contributes to Their Inter-Individual Differences. Biological & pharmaceutical bulletin. 2021. 44. 11. 1635-1644