Kihara Shinji

キハラシンジ | Kihara Shinji

Affiliation and department：
Homepage URL (1)： http://www.kihara-lab.jp/index.html

Research field (3)： Internal medicine - General , Metabolism and endocrinology , Cardiology

Research keywords (3)：内分泌代謝内科学 , Cardioangiology , Endocrinology and Metabolism

Research theme for competitive and other funds (23)：

2021 - 2024 Development of diagnostic method for autoimmune dyslipidemia
2018 - 2022 アディポカイン制御因子の解明に基づく動脈硬化診断法の開発
2018 - 2021 Development of diagnosis methods for autoimmune dyslipidemia
2015 - 2018 Development of diagnostic methods for autoimmune dyslipidemia
2015 - 2018 アディポカイン結合蛋白を標的にした動脈硬化診断法の開発

2015 - 2017 Development of diagnostic method for lifestyle-related disease risk targeting peripheral blood mononuclear cells

2010 - 2012 Mechanism of adiponectin binding proteinson vascularmetabolism.

2009 - 2011 Impact of visceral fat and adiponectin on association between sleep apnea and cardiovascular diseases

2009 - 2011 A role of adiponectin in the pathogenesis of GERD and the development of adenocarcinoma from Barrett' s esophagus

2007 - 2008 Studies on hypoadiponectinemia and adipose-expressed genes for the prevention of cardiovascular diseases

2006 - 2007 Elucidation of pbysiological significance in the fat-derived molecules with those expressions regulated by feeding and the importance of those molecules in the development of life-style related disease.

2003 - 2007 Pathophysiological Role of Adipocyte Expressed Genes in Common Disease

2005 - 2006 MOLECULAR MECHANISM OF ADIPONECTIN-DEFICIENCY ON HYPERTENSION AND CARDIVASCULAR REMODELING

2005 - 2006 The significance of adipocyte-specific glycerol channel, aquaporin adipose for life-style related diseases.

2005 - 2006 The significance of adipocvte-specific glycerol channel, aquaporin adipose for life-style related diseases.

2003 - 2004 Probing of physiological significance of adipocyte-specific glycerol channel and its application to the treatment of diabetes mellitus.

2001 - 2004 脂肪細胞水チャネル分子、aquaporin adiposeの解析-生理機能およびグリセロールチャネル代謝における意義-

2002 - 2003 Genetic and functional analyses of adiponectin in insulin resistance syndrome

2001 - 2002 Clarification of the physiological mechanism in a novel adipose specific glycerol channel discovered by us

2001 - 2002 Role of a novel visceral-derived endocrine factor in the development of atherosclerosis.

2000 - 2001 Role of an adipocyte-derived protein, adiponectin, in insulin resistance

1999 - 2000 Clarification of molecular mechanism in anti-atherogenic action of an adipocytedrived matrix protein, adiponectin.

脂肪細胞由来生理活性物質の糖・脂質代謝及び血管病に及ぼす役割

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Papers (213)：

Hiromi Uekita, Hiroyasu Yamamoto, Ryu Niinaga, Noriko Yamane, Manami Yoshii, Keiko Yamauchi-Takihara, Shinji Kihara. Reciprocal association of serum Mac-2 binding protein and HDL-cholesterol concentrations. Clinica chimica acta; international journal of clinical chemistry. 2021. 516. 142-148
西澤均, 木原進士. 【検査室からみた生活習慣病-症例から学ぶ病態と検査データの見方】実践編この検査データをどう読みますか? 症例(4). Medical Technology. 2020. 48. 11. 1167-1172
Takafumi Kawai, Kento Kayama, Shoki Tatsumi, Sharmin Akter, Nana Miyawaki, Yoshifumi Okochi, Manabu Abe, Kenji Sakimura, Hiroyasu Yamamoto, Shinji Kihara, et al. Regulation of hepatic oxidative stress by voltage-gated proton channels (Hv1/VSOP) in Kupffer cells and its potential relationship with glucose metabolism. The FASEB Journal. 2020
Yamamoto H, Kawamura M, Kochi I, Imai M, Murata Y, Suzuki T, Chen Y, Hashimoto K, Kihara S. Serum Anti-Apo B Antibody Level as Residual CVD Marker in DM Patients under Statin Treatment. Journal of Atherosclerosis and Thrombosis. 2019. 26. 10. 931-943
Inoue M, Kawamura M, Yamamoto H, Takahashi T, Kihara S. Juvenile-onset systemic lupus erythematosus with severe hypertriglyceridemia induced by anti-apolipoprotein C-II antibody. Pediatrics International. 2019. 61. 2. 201-203

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MISC (204)：

Shinji Kihara, Yuji Matsuzawa. Fat Distribution and Cardiovascular Disease Risk. Current Cardiovascular Risk Reports. 2015. 9. 3
胡迪, 宮田佑吾, 福原淳範, 大屋健, 大月道夫, 木原進士, 下村伊一郎. マクロファージにおけるアディポネクチンの標的因子とシグナル経路の解析. 糖尿病. 2012. 55. Supplement 1. S.115
胡迪, 福原淳範, 宮田佑吾, 木原進士, 大月道夫, 下村伊一郎. アディポネクチンはリンパ管新生因子の発現を制御する. 肥満研究. 2011. 17. Supplement. 203
Unusual adipocytokines. Japanese journal of clinical medicine. 2011. 69. 237-240
KIHARA Shinji. Role of Adipocytokines in Vascular Diseases. 2010. 50. 5. 549-554

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Professional career (1)：

(BLANK) (Osaka University)

Work history (9)：

2010/08 - 現在大阪大学教授生体情報科学
2010/08/01 - 現在 Osaka University Graduate School of Medicine Division of Health Sciences Professor
2007/06/01 - 2010/07/31 Osaka University Division of Internal Medicine Associate Professor
2007/06 - 2010/07 大阪大学講師内分泌・代謝内科学
2000/10 - 2007/05 大阪大学助手分子制御内科学

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Awards (2)：

2001/10 - 日本べーリンガーインゲルハイム第38回ベルツ賞
2000/10 - 日本肥満学会日本肥満学会賞

Association Membership(s) (12)：

日本肥満学会 , 日本内分泌学会 , 日本生化学会 , 米国心臓学会(American Heart Association) , 日本動脈硬化学会 , 日本糖尿病学会 , 日本循環器学会 , 日本内科学会 , 日本臨床化学会 , 日本臨床検査医学会 , American Diabetes Association , 米国循環器学会

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