Rchr

J-GLOBAL ID：200901061253708554 Update date: Feb. 01, 2024

I Igarashi

イガラシイクオ | I Igarashi

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www.obihiro.ac.jp/~protozoa/

Research field (1)： Veterinary medicine

Research keywords (13)： human babesiosis , bovine babesiosis , equine babesiosis (piroplasmosis) , molecular epidemiological survey , prevention , treatment , giagnosis , protozoan diseases , molecular analysis , in vitro culture , protozoa , Tropical Veterinary Medicine , Protozoan Molecular Diagnosis

Research theme for competitive and other funds (29)：

2010 - 2010 バベシア原虫の完全長cDNAライブラリーを活用した新規診断・予防用抗原の探索
2007 - 2010 Molecular epidemiological survey on Babesia parasites in Asia and Africa
2007 - 2009 Elucidation of erythrocyte recognition and invasion by Babesia parasites
2006 - 2009 Development of petide array for diagnosis fo important protozoan diseases using one drop of blood sample.
2005 - 2008 Epidemiological study on animal tick-borne protozoan diseases in Korea and China

2006 - 2007 糖転移酵素ノックアウトマウスを用いたバベシア原虫による赤血球感染機構の解明

2001 - 2004 Development of international standard diagnostic method for equine babesiosis

2001 - 2003 Epidemiological investigation of protozoan diseases in China

2000 - 2002 Viral Vector Vaccine Development for Bovine Piroplasmosis in Japan

2000 - 2002 Molecular Seroepidemiologic Studies on Piroplasmosis of Domestic Animals in Brazil

1999 - 2002 Control of toxoplasmosis by inducing Th1 helper cells

1999 - 2002 Studies on control of animal protozoan diseases by recombinant herpesvirus vector vaccines

1999 - 2001 Epidemiology on piroplasmosis of demestic animals in Mongolia

1999 - 2001 Developmental biotechnological and molecular immunological analysis of host defense mechanisms against protozoan infection

1999 - 2001 Molecular Epidemiological Surveillance of Equine Babesiosis in Japan

1998 - 2001 Molecular analysis of intraerythrocytic parasite population dinamics and acquirement of biological diversity

1998 - 2000 Control of Criptosporidium parvum infection in calves by recombinant herpesvirus vector vaccine

1997 - 2000 Analysis on protective antigen of Babesia parasites by developmental engineering

1999 - Studies on receptor and ligand on Babesia

1995 - 1998 Studies on newly synthesized peptides having parasitocidal activity, and their mechanisms on host immune repsponses.

1996 - 1997 Deveropmental biotechnological analysis of host defense mechanisms against protozoan infection

1997 - In vitro cultivation of Babesia parasites and it's application for diagnosis

1994 - 1996 Studies on newly synthesized peptide as an immunoregulator against protozoan infection

1994 - 1995 Establishment of continuous in vitro cultivation of bovine and equine Babesia parasites and it's application to diagnostic methods

1991 - 1994 Studies on no-specifical immunoregulatory effects to the host by the addministration of newly activated-peptides derived from Toxoplasma lysate substance

1991 - 1993 Basic Research on Protective Immunity against Experimental Hemoprotozoan Infections

1991 - 1993 Molecular Immunological Studies on The Prevention and Diagnoses of Protozoan Infection

1991 - Immunological Studies on Hemoprotozoan Diseases

Development of serodiagnostic tests for protozoan infections

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Papers (307)：

Tayebwa DS, Vudriko P, Tuvshintulga B, Guswanto A, Nugraha AB, Gantuya S, Batiha GE, Musinguzi SP, Komugisha M, Bbira JS, et al. Molecular epidemiology of Babesia species, Theileria parva, and Anaplasma marginale infecting cattle and the tick control malpractices in Central and Eastern Uganda. Ticks and tick-borne diseases. 2018. 9. 6. 1475-1483
Sivakumar T, Tuvshintulga B, Zhyldyz A, Kothalawala H, Yapa PR, Kanagaratnam R, Vimalakumar SC, Abeysekera TS, Weerasingha AS, Yamagishi J, et al. Genetic analysis of Babesia isolates from cattle with clinical babesiosis in Sri Lanka. Journal of clinical microbiology. 2018. 56. 11
Shunya Shibata, Thillaiampalam Sivakumar, Ikuo Igarashi, Rika Umemiya-Shirafuji, Hisashi Inokuma, Shinya Fukumoto, Naoaki Yokoyama. Epidemiological survey of a cervine Theileria in wild deer, questing ticks, and cattle in Hokkaido, Japan. Ticks and tick-borne diseases. 2018. 9. 5. 1235-1240
Umemiya-Shirafuji R, Hatta T, Okubo K, Sato M, Maeda H, Kume A, Yokoyama N, Igarashi I, Tsuji N, Fujisaki K, et al. Transovarial persistence of Babesia ovata DNA in a hard tick, Haemaphysalis longicornis, in a semi-artificial mouse skin membrane feeding system. Acta parasitologica. 2018. 63. 2. 433-433
Azirwan Guswanto, Arifin Budiman Nugraha, Bumduuren Tuvshintulga, Dickson Stuart Tayebwa, Mohamed Abdo Rizk, Gaber El-Saber Batiha, Sambuu Gantuya, Thillaiampalam Sivakumar, Naoaki Yokoyama, Ikuo Igarashi. 17-DMAG inhibits the multiplication of several Babesia species and Theileria equi on in vitro cultures, and Babesia microti in mice. International Journal for Parasitology: Drugs and Drug Resistance. 2018. 8. 1. 104-111

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MISC (121)：

Igarashi I. Activities of National Research Center for Protozoan Diseases as OIE Reference Centres. Journal of the Japan Veterinary Medical Associatgion. 2012. 65. 11. 825-828
M Okamura, N Yokoyama, NPALK Wickramathilaka, N Takabatake, Y Ikehara, Igarashi, I. Babesia caballi and Babesia equi: Implications of host sialic acids in erythrocyte infection. EXPERIMENTAL PARASITOLOGY. 2005. 110. 4. 406-411
OMM Thekisoe, N Inoue, N Kuboki, D Tuntasuvan, W Bunnoy, S Borisutsuwan, Igarashi, I, C Sugimoto. Evaluation of loop-mediated isothermal amplification (LAMP), PCR and parasitological tests for detection of Trypanosoma evansi in experimentally infected pigs. VETERINARY PARASITOLOGY. 2005. 130. 3-4. 327-330
S Bork, M Okamura, T Matsuo, S Kumar, N Yokoyama, Igarashi, I. Host serum modifies the drug susceptibility of Babesia bovis in vitro. PARASITOLOGY. 2005. 130. 489-492
A Alhassan, W Pumidonming, M Okamura, H Hirata, B Battsetseg, K Fujisaki, N Yokoyama, Igarashi, I. Development of a single-round and multiplex PCR method for the simultaneous detection of Babesia caballi and Babesia equi in horse blood. VETERINARY PARASITOLOGY. 2005. 129. 1-2. 43-49

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Patents (12)：

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Books (13)：

Tea in Health and Disease Prevention
Elsevier 2012
Drug Discovery in Infectious Diseases:Apicomplexan Parasites: Molecular Approaches toward Targeted Drug Development
Wiley-Blackwell 2011
犬・猫の感染症と寄生虫病(5分間治療ガイド)
インターズー 2007
Asian Parasitology Vol. 4
AAA Committee 2005
獣医公衆衛生学、第3版、
文永堂出版 2004

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Lectures and oral presentations (62)：

Diagnosisi for equine piroplasmosis.
(International Workshop for south asian association for regional cooperation countries paraticipants on molecular diagnosis of equine piroplamosis 2012)
Receent progress of of the diagnosis for equine piroplamosis
(9th International Conference on equine infectious diseases 2012)
フタトゲチマダニ人工吸血系の確立とBabesia ovata感染マダニ作出への応用
(第154回日本獣医学会学術集会 2012)
Validating M17 leucine aminopeptidase of Babesia parasites as a molecular drug target
(2012)
Epidemiology of bovine Babesia and Theileria parasites in Sri Lanka
(2012)

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Works (8)：

International molecular survey on babesiosis
Igarashi I 1998 - 現在
Establishment of in vitro culture of Babesia
1998 - 現在
mechanisms of invasion and development of Babesia in erythrocytes
Igarashi I 1997 - 現在
Development of diagnostic methods for babesiosis
Igarashi I 1995 - 現在
Development of chemotherapy for babesiosis
Igarashi I 1990 - 現在

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Education (3)：

1979 - 1983 Gunma University Graduate School of Medicine Social Medicine (Parasitology)
1977 - 1979 Obihiro University of Agriculture and Veterinary Medicine Graduate School of Animal Science Veterinary Medicine
1973 - 1977 Obihiro University of Agriculture and Veterinary Medicine Faculty of Animal Science Veterinary Medicine

Professional career (2)：

Ph.D (Gunma University)
Master of Veterinary Medicine (Obihiro University of Agriculture and Veterinary Medicine)

Work history (13)：

2007/05 - 現在 World Organisation for Animal Health (OIE) Expert of bovine babesiosos and equine piroplasmaosis
2006/04 - 現在 Graduate School of Animal and Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine Profesoor
2000/04 - 現在 National Research Center for Protozoan iseases Professor
2002/02 - 2010/03 National Research Center for Protozoan iseases Director
2002/02 - 2010/03 National Research Center for Protozoan Diseases Director

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Committee career (40)：

2013/01 - 現在日独原虫病協会会長
2012/10 - 現在 PLOS ONE Academic Editor
2012/05 - 現在長崎大学熱帯医学研究所熱帯医学研究拠点運営委員会委員長
2012/04 - 現在日本獣医寄生虫学会副理事長
2012/04 - 現在日本熱帯医学会理事

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Awards (4)：

2019/04 - 読売新聞社読売農学賞家畜の原虫病に対する診断、治療、予防法の開発に関する研究
2019/04 - 日本農学会日本農学賞家畜の原虫病に対する診断、治療、予防法の開発に関する研究
2018/03 - Katsurada Award Studies on development of diagnostics and treatment for piroplamosis
2000/04 - The Japanese Society of Veterinary Science Veterinary Science Award Establishment of in vitro culture of Babesia and it's application for chemotherapy and dianosis

Association Membership(s) (15)：

Japanese-German Society of Protozoan Diseases , Japanese Society of Veterinary Parasitology , American Society for Micorbiology , Australia Society of Parasitology , 世界獣医寄生虫学会 , JAPANESE SOCIETY OF TROPICAL MEDICINE , THE JAPANESE SOCIETY OF PARASITOLOGY , JAPANESE SOCIETY OF VETERINARY SCIENCE , Japanese Society for Tropical medicine and Hygiene , Japanese Socciety of Parasitology , Japnese Societ of Veterinary Science , Australian Society for parasitology , American Society for Microbiology , World Association for Advancement of Veterinary Parasitology , World Association for Advancedment of Veterinary Parasitology

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