Nishimura Shigenori

ニシムラシゲノリ | Nishimura Shigenori

Affiliation and department：
Homepage URL (1)： http://www.bioinfo.osakafu-u.ac.jp/~inuit/

Research field (3)： Biophysics , Structural biochemistry , Molecular biochemistry

Research keywords (6)：構造生物学 , 生物物理化学 , 蛋白質工学 , Structure biology , Biophisycal chemistry , Protein Engineering

Research theme for competitive and other funds (13)：

2021 - 2025 Development of new drug for African trypanosomiasis based on elucidation of the mechanism of antiprotozoal action by ribavirin.
2017 - 2021 Molecular basis and development of transglycosylation reaction of maltotriose-forming amylase
2017 - 2020 Challenge for treatment of dog allergy by allergen immunotherapy using hypoallergenic vaccine
2014 - 2017 Molecular basis for the recognition of the substrate and for the transglycosylation reaction of an exo-type alpha-amylase.
2013 - 2016 Development of novel therapeutic agents against African sleeping sickness targeted for GMP reductase.

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Papers (27)：

Masatoshi Nakatsuji, Keisuke Sugiura, Keisuke Suda, Michiko Sakurai, Miki Ubatani, Haruka Muroya, Rina Okubo, Ryo Noguchi, Yoichi Kamata, Yuma Fukutomi, et al. Structure-based prediction of the IgE epitopes of the major dog allergen Can f 1. The FEBS journal. 2021. 289. 6. 1668-1679
Akira Imamura, Tetsuya Okada, Hikaru Mase, Takuya Otani, Tomoka Kobayashi, Manatsu Tamura, Bruno Kilunga Kubata, Katsuaki Inoue, Robert P Rambo, Susumu Uchiyama, et al. Allosteric regulation accompanied by oligomeric state changes of Trypanosoma brucei GMP reductase through cystathionine-β-synthase domain. Nature communications. 2020. 11. 1. 1837-1837
Kitaoku Y, Nishimura S, Hirono T, Suginta W, Ohnuma T, Fukamizo T. Structures and chitin-binding properties of two N-terminal lysin motifs (LysMs) found in a chitinase from Volvox carteri. Glycobiology. 2019. 29. 7. 565-575
Kenji Yamamoto, Osamu Ishibashi, Keisuke Sugiura, Miki Ubatani, Masaya Sakaguchi, Masatoshi Nakatsuji, Shigeru Shimamoto, Masanori Noda, Susumu Uchiyama, Yuma Fukutomi, et al. Crystal structure of the dog allergen Can f 6 and structure-based implications of its cross-reactivity with the cat allergen Fel d 4. Scientific reports. 2019. 9. 1. 1503-1503
Yuika Kunishige, Marin Iwai, Masami Nakazawa, Mitsuhiro Ueda, Toshiji Tada, Shigenori Nishimura, Tatsuji Sakamoto. Crystal structure of exo-rhamnogalacturonan lyase from Penicillium chrysogenum as a member of polysaccharide lyase family 26. FEBS Letters. 2018. 592. 8. 1378-1388

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MISC (41)：

山本賢史, 石橋宰, 杉浦慶亮, 姥谷美樹, 中辻匡俊, 島本茂, 野田勝紀, 内山進, 福冨友馬, 西村重徳, et al. イヌアレルゲンCan f 6のX線結晶構造解析と交差反応性を利用したB細胞エピトープの同定. 日本蛋白質科学会年会プログラム・要旨集. 2018. 18th
Akira Imamura, Takuya Otani, Takuya Otani, Manatsu Tamura, Tomoka Kobayashi, Asami Shibata, Tetsuya Okada, Shigenori Nishimura, Takashi Inui. Role of cystathionine beta synthase module in Trypanosoma brucei GMP reductase. PROTEIN SCIENCE. 2017. 26. 85-86
國重由花, 岩井真凜, 中澤昌美, 上田光宏, 多田俊治, 西村重徳, 阪本龍司. Penicillium chrysogenum由来新規エキソ-ラムノガラクチュロナンリアーゼのX線結晶構造解析. 日本農芸化学会中四国支部講演会講演要旨集(Web). 2017. 49th
國重由花, 岩井麻凛, 中澤昌美, 上田光宏, 多田俊治, 西村重徳, 阪本龍司. Penicillium chrysogenum由来新規エキソラムノガラクチュロナンリアーゼのX線結晶構造解析. 応用糖質科学. 2016. 6. 3
國重由花, 岩井麻凛, 中澤昌美, 上田光宏, 多田俊治, 西村重徳, 阪本龍司. Penicillium chrysogenum由来新規エキソ-ラムノガラクチュロナンリアーゼの反応特性解析およびX線結晶構造解析. 日本農芸化学会大会講演要旨集(Web). 2016. 2016

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Education (2)：

Professional career (1)：

Association Membership(s) (5)：

THE JAPANESE SOCIETY OF APPLIED GLYCOSCIENCE , THE NUCLEAR MAGNETIC RESONANCE SOCIETY OF JAPAN , 日本蛋白質科学会 , 日本農芸化学会 , 日本生物物理学会

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