Rchr
J-GLOBAL ID：200901061546857040
Update date: Mar. 18, 2024
Horio Shuhei
ホリオ シュウヘイ | Horio Shuhei
Affiliation and department：
Job title：
Assistant Professor
Research field (3)：
Pharmacology
, Physiology
, Neuroscience - general
Research keywords (9)：
Neural pathway
, CRH
, ヒスタミン神経系
, 視床下部
, 摂食調節
, 包括脳ネットワーク
, 環境生理学
, 神経科学
, Pharmacology in General
Research theme for competitive and other funds (20)：
- 2020 - 2024 Identification of CRF neurons in the hypothalamic paraventricular nucleus that are involved in feeding inhibition
- 2016 - 2019 神経経路選択的な遺伝子発現を用いた視床下部摂食調節回路の解明
- 2012 - 2015 Comprehensive study on the neural circuit of feeding regulation targeting hypothalamic histamine H1 receptor-expressing neurons
- 2011 - 2012 摂食抑制ニューロンの可視化
- 2009 - 2011 Study on the neural network of feeding regulation by selective ablation of histamine H1 receptor-expressing neurons
- 2001 - 2002 Study on the role of histamine H1 receptors in the central nervous system using gene-targeted mouse
- 1999 - 2000 Research on transcription of mRNA of inducible NO synthase and supression of its degradation by proinflammatory cytokine.
- 1997 - 1998 Cytopharmacological and molecular biological study on induction of NO synthase by proinflammatory cytokines
- 1996 - 1996 血管内皮細胞における容量性Ca流入機序に関する研究
- 1996 - 1996 血管のNO産生系情報伝達におけるCaとTyrosine kinaseの役割の解明
- 1995 - 1995 血管のNO産生系におけるCa^<++>とTyrosine kinaseの役割の解明
- 1995 - 1995 血管内皮細胞におけるCa流入機序に関する生化学的薬理学的研究
- 1994 - 1994 血管内皮細胞におけるチロシン・キナーゼを介したCa流入機構解明に関する研究
- 1994 - 1994 血管におけるNO合成酵素の誘導機構の解明
- 1991 - 1993 Studes on the L-arginine-derived, endothelium-independent relaxing factor
- 1988 - 1989 Possible Mechanisms of Age-associated Decrease in Vascular Functions
- 1987 - 1987 アセチルコリン及びヒスタミンによる脱感作現象に関与する因子についての研究
- 1985 - 1987 Age-related decrease in vqsodilation and anti-aggregating function of vascular endothelium
- Study on the central role of histamine H1 receptor by using gene-targetted mice
- The study on the mechanism of desensitization of histamine receptor
Show all
Papers (35)：
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Masahiro Morishita, Kaito Kobayashi, Moeri Mitsuzuka, Ryo Takagi, Kota Ono, Rami Momma, Yousuke Tsuneoka, Shuhei Horio, Shinji Tsukahara. Two-Step Actions of Testicular Androgens in the Organization of a Male-Specific Neural Pathway from the Medial Preoptic Area to the Ventral Tegmental Area for Modulating Sexually Motivated Behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023. 43. 44. 7322-7336
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Junko Kono, Kohtarou Konno, Ashraf Hossain Talukder, Toshimitsu Fuse, Manabu Abe, Katsuya Uchida, Shuhei Horio, Kenji Sakimura, Masahiko Watanabe, Keiichi Itoi. Distribution of corticotropin-releasing factor neurons in the mouse brain: a study using corticotropin-releasing factor-modified yellow fluorescent protein knock-in mouse. BRAIN STRUCTURE & FUNCTION. 2017. 222. 4. 1705-1732
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Horio Shuhei. 3PT215 Histamine HI receptor-expressing neurons in the anterior part of the hypothalamic paraventricular nucleus inhibit food intake(The 50th Annual Meeting of the Biophysical Society of Japan). Seibutsu Butsuri. 2012. 52. S177
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Shuhei Horio, Shuji Kitaike, Tetsuya Shiuchi, Yasuhiko Minokoshi, Makoto Sanbo, Takahiro Hirabayashi, Takeshi Yagi, Nobuyuki Kai, Kazuto Kobayashi, Takashi Ueyama, et al. Selective ablation of histamine H1 receptor-expressing neurons in the paraventricular nucleus of the hypothalamus to study their role in the regulation of food intake. NEUROSCIENCE RESEARCH. 2011. 71. E162-E162
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Shuhei Horio, Katsumi Fujimoto, Hiroyuki Mizuguchi, Hiroyuki Fukui. Interleukin-4 up-regulates histamine H1 receptors by activation of H1 receptor gene transcription. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 2010. 381. 4. 305-313
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MISC (64)：
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森下雅大, 三塚萌里, 小野浩太, 恒岡洋右, 堀尾修平, 加藤成樹, 小林和人, 塚原伸治. 内側視索前野の性的二型性を確立するニューロンの形態学的特性,生理機能および性差構築機構の解析. 日本神経内分泌学会学術集会プログラム・抄録集. 2021. 47th. 5. 1244-1244
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森下雅大, 小野浩太, 恒岡洋右, 堀尾修平, 加藤成樹, 小林和人, 塚原伸治. マウスの内側視索前野に存在するカルビンディンニューロンの神経投射. 日本比較内分泌学会大会及びシンポジウムプログラム・講演要旨. 2019. 44th
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堀尾修平. 視床下部室傍核のCRFニューロンの脳内投射部位の特定とその機能. 日本生理学雑誌(Web). 2018. 80. 3. 40-41 (WEB ONLY)
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堀尾修平, 山形聡, 小林憲太, 加藤成樹, 崎村建司, 上山敬司, 小林和人, 井樋慶一. 視床下部室傍核のCRFニューロンの細分類とその機能. 日本神経内分泌学会学術集会プログラム・抄録集. 2017. 44th. 39
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堀尾修平, 箕越靖彦, 上山敬司, 小林和人. 視床下部室傍核の神経内分泌ニューロンとヒスタミンH1受容体発現ニューロンの関係. 日本内分泌学会雑誌. 2015. 91. 2. 519
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Books (4)：
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Desensitization of muscarinic and ATP receptors in rat thoracic endothelial cells : the role of eftracellular Ca<sup>2+</sup>.
The Biology of Nitric Oxide Part 6. (Ed. Moncada at al. )Portland Press. 1998
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Desensitization of muscarinic and ATP receptors in rat thoracic endothelial cells : the role of eftracellular Ca<sup>2+</sup>.
The Biology of Nitric Oxide Part 6. (Ed. Moncada at al. )Portland Press. 1998
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Desensitization of Histamine H1 Receptors in Smooth Muscle.
Receptor Desensitigation and Ca<sup>2+</sup>-Signaling (Ed. M.K. Uchida). Japan Scientific Societies Press. 1996
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Desensitization of Histamine H1 Receptors in Smooth Muscle.
Receptor Desensitigation and Ca<sup>2+</sup>-Signaling (Ed. M.K. Uchida). Japan Scientific Societies Press. 1996
Professional career (2)：
- (BLANK) (The University of Tokyo)
- (BLANK) (Kyushu University)
Work history (4)：
- 2018/04 - 現在 National Institutes of Natural Sciences
- 2007 - 2008 The University of Tokushima Institute of Health Biosciences The University of Tokushima Graduate School
- 2005 - 2007 The University of Tokushima Institute of Health Biosciences The University of Tokushima Graduate School
- 1981 - 2001 University of Tokushima, Research assistant
Association Membership(s) (6)：
THE JAPAN NEUROSCIENCE SOCIETY
, PHYSIOLOGICAL SOCIETY OF JAPAN
, 北米神経科学会
, 日本生物物理学会
, 日本薬学会
, 日本薬理学会
