Tokumoto Toshinobu

トクモトトシノブ | Tokumoto Toshinobu

Affiliation and department：
Job title： Professor

Research field (1)： Developmental biology

Research keywords (5)： sex change , ovulation , proteasome , membrane steroid receptors , oocyte maturation

Research theme for competitive and other funds (14)：

2023 - 2026 ステロイド膜受容体の機能解析を中心とした卵成熟・排卵誘導機構の解明
2020 - 2023 Functions of membrane steroid receptors and molecular mechanism of oocyte maturation and ovulation
2016 - 2019 Studies on functions of membrane steroid receptors and molecular mechanism of oocyte maturation and ovulation
2015 - 2018 Identification of hormonal active compounds found in coral reef seawater in Mauritius
2013 - 2016 Studies on functions of membrane steroid receptors and molecular mechanism of oocyte maturation and ovulation

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Papers (91)：

Syunsuke Seki, Kaoru Ohura, Takehiro Miyazaki, Abdullah An Naser, Shuji Takabayashi, Eisei Tsutsumi, Toshinobu Tokumoto. The Mc4r gene is responsible for the development of experimentally induced testicular teratomas. Scientific Reports. 2023. 13. 1. 1-9
Mrityunjoy Acharjee, Md. Hasan Ali, Md. Maisum, Sarwar Jyoti, Md. Rezanujjaman, Md. Maksudul Hassan, Md. Rubel Rana, Md. Forhad Hossain, Shinya Kodani, Toshinobu Tokumoto. The antagonistic activity of Padina arborescens extracts on mPRα. Natural Product Research. 2022. 37. 11. 1872-1876
Mst. Habiba Mostari, Md. Mostafizur Rahaman, Mst. Afroza Akhter, Md. Hasan Ali, Tomohiro Sasanami, Toshinobu Tokumoto. Transgenerational effects of bisphenol A on zebrafish reproductive tissues and sperm motility. Reproductive Toxicology. 2022. 109. 31-38
Ali Md. Hasan, Md. Maisum, Sarwar Jyoti, Md. Rubel Rana, Md. Rezanujjaman, Toshinobu Tokumoto. Purification and identification of the 20S proteasome complex from zebrafish. Zebrafish. 2022. 19. 1. 18-23
Md. Maisum, Sarwar Jyoti, Md. Rubel Rana, Md. Hasan Ali, Toshinobu Tokumoto. Establishment of a steroid binding assay for membrane progesterone receptor alpha (PAQR7) by using graphene quantum dots (GQDs). Biochemical and Biophysical Research Communications. 2022. 592. 1. 1-6

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MISC (27)：

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Patents (4)：

Books (10)：

Understanding neuroendocrine regulatory pathways of sexual behavior in teleosts
Aquaculture and Fisheries 2023
Morphological and physiological studies on sex change in tropical fish: Sexual plasticity of the ovaries of hermaphroditic and gonochoristic fish
The Japanese Coral Reef Society 2022
Membrane progestin receptor, a key mediator of final oocyte maturation in fish
NOVA Science Publishers Inc., USA 2018
ナノバイオ・テクノロジー
静岡学術出版 2016
ZEBRAFISH AS A MODEL FOR REPRODUCTIVE BIOLOGY AND ENVIRONMENTAL SCREENING
NOVA Science Publishers Inc., USA 2014

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Lectures and oral presentations (38)：

Phenotypic analysis of gene knock-out strains of highly upregulated genes during ovulation in zebrafish
(International Symposium on Reproductive Physiology of Fish 12th ISRPF 2023)
Expression and purification of human membrane estrogen receptor (hmER) and establishment of high throughput assays using GQDs
(第46回日本比較内分泌学会大会及びシンポジウム 2022)
ゲノム編集による新たなマウステラトーマ形成原因遺伝子の同定
(静岡実験動物研究会令和4年度研究発表会 2022)
ゼブラフィッシュにおける排卵関連遺伝子 prss59.1 の機能解析
(日本動物学会第93回早稲田大会 2022)
ゼブラフィッシュにおけるStmは卵膜上のノブ型構造及び卵膜孔の形成に関与する
(日本動物学会第93回早稲田大会 2022)

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Education (4)：

- 1994 The Graduate University for Advanced Studies
- 1994 The Graduate University for Advanced Studies Graduate School, Division of Life Science
- 1989 Shizuoka University Faculty of Science
- 1989 Shizuoka University Faculty of Science

Professional career (1)：

Committee career (1)：

Association Membership(s) (2)：

日本比較内分泌学会 , 日本動物学会

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